Results 171 to 180 of about 3,184,534 (315)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Glutamate as a therapeutic strategy to promote liver regeneration

open access: yesClinical and Translational Medicine
María del Mar Rigual, Nabil Djouder
doaj   +1 more source

Preliminary Insights into Association of Growth Factors with Hypodontia: A Clinical Study. [PDF]

open access: yesClin Cosmet Investig Dent
Alenzi RH   +5 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

West African agricultural development in the 60's.

open access: yes, 1973
Meeting: International Conference on Factors of Agricultural Growth in West Africa, Apr. 1971, Legon, Accra, GHDue to copyright restrictions, this item cannot be sharedIDRC governor.
Oluwasanmi, H.A.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Optimized Centrifugation and Activation Protocol for the Preparation of Plasma Rich in Growth Factors in Pigs. [PDF]

open access: yesBiomedicines
Taiana MM   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Are health factors important for regional growth and convergence? An empirical analysis for the Portuguese districts [PDF]

open access: yes
The aim of this study is to analyze the impact of health factors on economic growth and convergence across the Portuguese regions at the district level.
Ana Poças, Elias Soukiazis
core  

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