Results 181 to 190 of about 3,184,534 (315)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A QUANTITATIVE ASSESSMENT OF FACTORS CONTRIBUTING TO THE ECONOMIC GROWTH OF MICHIGAN REGIONS

open access: yes
Many studies in regional development and economic geography are focused on factors that determine regional growth. In this paper a review of existing studies of regional growth is presented.
Nizalov, Denys
core  

Growth and Growth Factors [PDF]

open access: yes, 2007
Evelien F Gevers   +2 more
openaire   +1 more source

Biological impact of adding albumin and silver nanoparticles to concentrated growth factors. [PDF]

open access: yesBMC Oral Health
Alshirah AA   +8 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

ADNP, a Microtubule Interacting Protein, Provides Neuroprotection Through End Binding Proteins and Tau: An Amplifier Effect

open access: yesFrontiers in Molecular Neuroscience, 2018
Illana Gozes   +2 more
doaj   +1 more source

A novel approach to Peyronie's disease: Intralesional injection of lyophilized platelet-derived growth factors. [PDF]

open access: yesCent European J Urol
Abdelrahman IFS   +7 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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