Results 271 to 280 of about 26,786,639 (354)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Combined concentrations and genetic variability of fibroblast growth factors predict cardiovascular risk in renal patients. [PDF]

open access: yesiScience
González-Rodríguez L   +10 more
europepmc   +1 more source

Salivary chemokines and growth factors in patients with ischemic stroke. [PDF]

open access: yesSci Rep
Forszt D   +7 more
europepmc   +1 more source

Anatomical and functional results of plasma rich in growth factors as a treatment for poor-prognosis macular holes. [PDF]

open access: yesRom J Ophthalmol
Caminal-Caramés M   +9 more
europepmc   +1 more source

Comprehensive Profiling of Cytokines and Growth Factors: Pathogenic Roles and Clinical Applications in Autoimmune Diseases. [PDF]

open access: yesInt J Mol Sci
Donniacuo A   +11 more
europepmc   +1 more source

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