Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin [PDF]
Brazilian Journal of Medical and Biological Research, 2006 Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
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Growth Hormone-Releasing Hormone in Diabetes [PDF]
Frontiers in Endocrinology, 2016 Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand +3 more
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Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice [PDF]
Clinics, 2012 OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing hormone receptors.
Cibele N. Peroni +7 more
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Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection [PDF]
Neural Regeneration Research, 2022 Both inflammation and anti-inflammation are involved in the protection of retinal cells. Antagonists of the hypothalamic growth hormone-releasing hormone receptor (GHRHR) have been shown to possess potent anti-inflammatory properties in experimental ...
Ling-Ping Cen +3 more
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Acromegaly Caused by Ectopic Growth Hormone Releasing Hormone Secretion: A Review [PDF]
Frontiers in Endocrinology, 2022 IntroductionEctopic acromegaly is a rare condition caused most frequently by growth hormone releasing hormone (GHRH) secretion from neuroendocrine tumors.
Iga Zendran +4 more
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Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation [PDF]
Nature Communications, 2023 Dysregulation of Th17 cell differentiation and pathogenicity contributes to multiple autoimmune and inflammatory diseases. Previously growth hormone releasing hormone receptor (GHRH-R) deficient mice have been reported to be less susceptible to the ...
Lin Du +11 more
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Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH). [PDF]
PLoS ONE, 2022 BackgroundGrowth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids.
Burcu Ayhan-Sahin +4 more
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Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice [PDF]
Frontiers in Cardiovascular Medicine, 2023 IntroductionVascular calcification (VC) is an independent risk factor for cardiovascular diseases. VC increases mortality of all-causes. VC is one of most common cardiovascular complications in type II diabetes.
Hao-Lin Ren +18 more
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Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease [PDF]
Cells, 2020 Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang +6 more
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Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs [PDF]
Frontiers in Veterinary ScienceAging leads to increased disease susceptibility and weakened immunity, a condition known as immunosenescence. The growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis plays a key role in both somatic ...
Min-Ok Ryu +9 more
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