Results 11 to 20 of about 73,914 (181)

Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice [PDF]

Scientific Reports, 2021
Besides its metabolic and endocrine effects, growth hormone (GH)-releasing hormone (GHRH) is involved in the modulation of inflammation. Recently synthetized GHRH antagonist MIA-690 and MR-409, GHRH agonist, developed by us have shown potent ...
Lucia Recinella, Annalisa Chiavaroli, Valentina Di Valerio, Serena Veschi, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Rossano Lattanzio, Luigi Brunetti, Sheila Leone   +13 more
doaj   +2 more sources

Growth hormone – releasing hormone in the context of inflammation and redox biology [PDF]

Frontiers in Immunology
Agnieszka Siejka, Nektarios Barabutis
doaj   +2 more sources

Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis

Frontiers in Veterinary Science, 2022
This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu, Lijie Gao, Fei Li, Jia Cui, Xinyu Yang, Yanhua Liu, Saijuan Chen, Saijuan Chen, Baojiang Chen   +8 more
doaj   +1 more source

Advanced bone age as an indicator facilitates the diagnosis of precocious puberty

Jornal de Pediatria (Versão em Português), 2018
Objective: Diagnosis of central precocious puberty has always been challenging in clinicalpractice. As an important method in the diagnosis of central precocious puberty, luteinizinghormone‐releasing hormone stimulation test is complex and time‐consuming.
Yue‐Qin Xu, Gui‐Mei Li, Yan Li
doaj   +3 more sources

Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2021
Purpose There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare.
Ah Young Cho, Su Yeong Ko, Jae Hee Lee, Eun Young Kim   +3 more
doaj   +1 more source

Growth Hormone-Releasing Hormone in Diabetes

Frontiers in Endocrinology, 2016
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand, Natalia A Tamarina, Andrew V Schally, Louis H Philipson   +3 more
doaj   +1 more source

Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice

Clinics, 2012
OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing hormone receptors.
Cibele N. Peroni, Cesar Y. Hayashida, Nancy Nascimento, Viviane C. Longuini, Rodrigo A. Toledo, Paolo Bartolini, Cyril Y. Bowers, Sergio P.A. Toledo   +7 more
doaj   +1 more source

Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin

Brazilian Journal of Medical and Biological Research, 2006
Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
doaj   +1 more source

Effect of tesamorelin in people with HIV with and without dorsocervical fat: Post hoc analysis of phase III double-blind placebo-controlled trial

Journal of Clinical and Translational Science, 2023
Tesamorelin, a synthetic growth hormone-releasing hormone, is indicated for the reduction of visceral adipose tissue (VAT) in people with HIV. Here, we performed a post hoc analysis of participants receiving tesamorelin for 26 weeks in a phase III ...
Farah Rahman, Taryn McLaughlin, Pedro Mesquita, Josee Morin, Diane Potvin, Marilyn De Chantal, Judith A. Aberg   +6 more
doaj   +1 more source

Effects of human growth hormone on gonadotropin-releasing hormone neurons in mice [PDF]

Korean Journal of Pediatrics, 2010
PurposeRecombinant human growth hormone (rhGH) has been widely used to treat short stature. However, there are some concerns that growth hormone treatment may induce skeletal maturation and early onset of puberty.
Janardhan P. Bhattarai, Shin Hye Kim, Seong Kyu Han, Mi Jung Park   +3 more
doaj   +1 more source