Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice [PDF]
Clinics, 2012 OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing hormone receptors.
Cibele N. Peroni +7 more
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Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice [PDF]
Frontiers in Cardiovascular Medicine, 2023 IntroductionVascular calcification (VC) is an independent risk factor for cardiovascular diseases. VC increases mortality of all-causes. VC is one of most common cardiovascular complications in type II diabetes.
Hao-Lin Ren +18 more
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Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs [PDF]
Frontiers in Veterinary ScienceAging leads to increased disease susceptibility and weakened immunity, a condition known as immunosenescence. The growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis plays a key role in both somatic ...
Min-Ok Ryu +9 more
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Protective Activities of Growth Hormone-Releasing Hormone Antagonists against Toxin-Induced Endothelial Injury [PDF]
EndocrinesGHRH regulates the secretion of GH from the anterior pituitary gland, previously associated with cancer progression and inflammation. An emerging body of evidence suggests that GHRHAnt support endothelial barrier function, but the mechanisms mediating ...
Saikat Fakir, Nektarios Barabutis
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Growth hormone-releasing hormone-secreting pulmonary neuroendocrine tumor associated with pituitary hyperplasia and somatotropinoma [PDF]
Archives of Endocrinology and Metabolism, 2021 SUMMARY Acromegaly caused by ectopic growth hormone-releasing hormone (GHRH)-secreting tumor is exceedingly rare. We report a case of acromegaly secondary to GHRH secretion by an incidentally diagnosed pulmonary neuroendocrine tumor (NET) and review 47 ...
Elisa B. Lamback +7 more
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eLife, 2013 We examine the impact of targeted disruption of growth hormone-releasing hormone (GHRH) in mice on longevity and the putative mechanisms of delayed aging.
Liou Y Sun +9 more
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Growth hormone – releasing hormone in the context of inflammation and redox biology [PDF]
Frontiers in ImmunologyAgnieszka Siejka, Nektarios Barabutis
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Effect of growth hormone releasing hormone on chondrocytes of osteoarthritis [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims To evaluate the effect and possible mechanism of growth hormone releasing hormone (GHRH) on chondrocytes of osteoarthritis (OA). Methods Articular chondrocytes were cultured and the expression of GHRH receptor in chondrocytes was detected.
Zhuoran LI, Yao LI
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Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis
Frontiers in Veterinary Science, 2022 This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu +8 more
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