Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +3 more
core +6 more sources
Significance An explanation has been lacking for the suppressive action of antagonists of growth hormone-releasing hormone receptors (GHRH-Rs) on cancers that do not express GHRH-Rs, an established target of the antagonists.
Xiao Xiong +9 more
semanticscholar +1 more source
Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
doaj +3 more sources
Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease
Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang +6 more
doaj +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source
Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty [PDF]
Purpose There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare.
Ah Young Cho +3 more
doaj +1 more source
Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Objective: Diagnosis of central precocious puberty has always been challenging in clinicalpractice. As an important method in the diagnosis of central precocious puberty, luteinizinghormone‐releasing hormone stimulation test is complex and time‐consuming.
Yue‐Qin Xu, Gui‐Mei Li, Yan Li
doaj +1 more source
Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source
A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats.
Herder, W.W. (Wouter) de +3 more
core +1 more source
Significance Malignant pleural mesothelioma (MPM) is an aggressive cancer with poor prognosis and limited treatment options. MPM remains a serious public health problem, and novel therapeutic strategies are urgently needed.
Tania Villanova +16 more
semanticscholar +1 more source

