Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma. [PDF]
Journal of Clinical Investigation, 1989 The plasma enzyme responsible for primary proteolytic cleavage of growth hormone-releasing hormone (GRH) at the 2-3 amino acid bond was characterized. Native GRH[GRH(1-44)-NH2 and GRH(1-40)-OH], and COOH-terminally shortened fragments [GRH(1-32)-NH2 and ...
L A Frohman +3 more
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Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone. [PDF]
Br J Clin Pharmacol, 2020 Aims: Growth hormone (GH) secretion is pulsatile and secretion varies highly between individuals. To understand and ultimately predict GH secretion, it is important to first delineate and quantify the interaction and variability in the biological ...
van Esdonk MJ +3 more
europepmc +3 more sources
Growth Hormone Response to L-Arginine Alone and Combined with Different Doses of Growth Hormone-Releasing Hormone: A Systematic Review and Meta-Analysis [PDF]
International Journal of Endocrinology, 2022 Background. Arginine (ARG) can modulate growth hormone (GH) release by suppressing its endogenous inhibitory regulator, somatostatin. ARG also induces the release of the GH-releasing hormone (GHRH).
Parvin Goli +3 more
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Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice [PDF]
Scientific Reports, 2021 Besides its metabolic and endocrine effects, growth hormone (GH)-releasing hormone (GHRH) is involved in the modulation of inflammation. Recently synthetized GHRH antagonist MIA-690 and MR-409, GHRH agonist, developed by us have shown potent ...
Lucia Recinella +13 more
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eLife, 2013 We examine the impact of targeted disruption of growth hormone-releasing hormone (GHRH) in mice on longevity and the putative mechanisms of delayed aging.
Liou Y Sun +9 more
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Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. [PDF]
PLoS ONE, 2010 BACKGROUND:Ghrelin targets the arcuate nucleus, from where growth hormone releasing hormone (GHRH) neurones trigger GH secretion. This hypothalamic nucleus also contains neuropeptide Y (NPY) neurons which play a master role in the effect of ghrelin on ...
Guillaume Osterstock +12 more
doaj +2 more sources
Growth hormone – releasing hormone in the context of inflammation and redox biology [PDF]
Frontiers in ImmunologyAgnieszka Siejka, Nektarios Barabutis
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Fenfluramine and Growth Hormone Release [PDF]
BMJ, 1973 D. L. F. Dunleavy +2 more
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Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis
Frontiers in Veterinary Science, 2022 This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu +8 more
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HORMON YANG BERPERAN DALAM PEMBENTUKAN SPERMATOZOA DAN OVUM [PDF]
, 2023 Normal men after stepping into the adolescent phase, they must produce sperm. Likewise, normal women after reaching the adolescent phase, they must produce ovum.
Puger, I Gusti Ngurah
core +2 more sources