Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance An explanation has been lacking for the suppressive action of antagonists of growth hormone-releasing hormone receptors (GHRH-Rs) on cancers that do not express GHRH-Rs, an established target of the antagonists.
Xiao Xiong +9 more
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Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2021 Purpose There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare.
Ah Young Cho +3 more
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Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Jornal de Pediatria (Versão em Português), 2018 Objective: Diagnosis of central precocious puberty has always been challenging in clinicalpractice. As an important method in the diagnosis of central precocious puberty, luteinizinghormone‐releasing hormone stimulation test is complex and time‐consuming.
Yue‐Qin Xu, Gui‐Mei Li, Yan Li
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Antagonistic analogs of growth hormone-releasing hormone increase the efficacy of treatment of triple negative breast cancer in nude mice with doxorubicin; A preclinical study [PDF]
, 2014 Introduction This study evaluated the effects of an antagonistic analog of growth hormone-releasing hormone, MIA-602, on tumor growth, response to doxorubicin, expression of drug resistance genes, and efflux pump function in human triple negative breast ...
Cai, Renzhi +6 more
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Induction of ovarian follicular development in the subadult frog Rana tigrina using luteinizing hormone releasing hormone-acetate [PDF]
, 1995 In the subadult Rana tigrina administration of 2 μg luteinizing hormone releasing hormone-acetate/frog six days a week for 4 weeks in April resulted in the formation of medium (in all 8 frogs) and large sized (in 4 out of 8 frogs) yolky oocytes and ...
Hoque, B., Naik, D. R., Saidapur, S. K.
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Journal of Clinical and Translational Science, 2023 Tesamorelin, a synthetic growth hormone-releasing hormone, is indicated for the reduction of visceral adipose tissue (VAT) in people with HIV. Here, we performed a post hoc analysis of participants receiving tesamorelin for 26 weeks in a phase III ...
Farah Rahman +6 more
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Single-cell phenotypic characterization of human pituitary GHomas and non-functioning adenomas based on hormone content and calcium responses to hypothalamic releasing hormones [PDF]
, 2015 Producción CientíficaHuman pituitary tumors are generally benign adenomas causing considerable morbidity due to excess hormone secretion, hypopituitarism, and other tumor mass effects.
Campos, José María de +6 more
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Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance This study demonstrates that the growth hormone-releasing hormone (GHRH) agonist MR409 exerts agonistic action in cancer cells in vitro but, in vivo, suppresses tumor growth of human experimental lung cancers and other cancers.
A. Schally +8 more
semanticscholar +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
, 1994 The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
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The effect of macrophages on the hormone-releasing cells in mouse pituitary [PDF]
, 2022 At the base of the brain is located the pituitary gland which secretes hormones to the bloodstream. Among other cells, the pituitary is resided by macrophages which take part in the immune system by phagocyting pathogens. I studied if macrophages have an
Laine, Elina
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