Results 61 to 70 of about 78,521 (217)

Identification of Two Types of Growth Hormone Receptor Mutations in Two Strains of Sex-linked Dwarf Chickens

The Journal of Poultry Science, 2009
Sex-linked dwarf (SLD) of White Leghorn (WL; S23MA line, Okazaki station, Japan) and White Plymouth Rock (WPR; 15 line, Hyogo station, Japan) strains were established from the MA line (WL) and 16 line (WPR) of a normal growing line, respectively ...
Kenichi Tahara, Akira Tsukada, Takanobu Hanai, Kenta Okumura, Kikumi Yamada, Atsushi Murai, Rikiya Yamamoto, Makoto Maeno, Noboru Saito, Kiyoshi Shimada   +9 more
doaj   +1 more source

Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension [PDF]

, 2021
Timothy A. Donlon, Randi Chen, Kamal Masaki, D. Craig Willcox, Richard Allsopp, Bradley J. Willcox, Brian J. Morris   +6 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evolving growth hormone deficiency: proof of concept

Frontiers in Endocrinology
IntroductionWe present the evolution of GHD in adolescent males with persistent growth failure, in whom the diagnosis was established after a second GH stimulation test (GST).MethodsWe performed a retrospective chart review of children who presented for ...
Sri Nikhita Chimatapu, Swathi Sethuram, Julie G. Samuels, Alexandra Klomhaus, Cassie Mintz, Martin O. Savage, Robert Rapaport   +6 more
doaj   +1 more source

OUTCOMES AFTER ADJUNCT GROWTH HORMONE TREATMENT WITH A LOW, INTERMEDIATE, OR HIGH DOSE PROTOCOL IN IVF CYCLES WITH POOR RESPONDERS [PDF]

, 2020
Reeva Makhijani, Stephanie M. Hallisey, Prachi N. Godiwala, Chantal Bartels, Daniel R. Grow, Lawrence Engmann, John Nulsen, Claudio Benadiva   +7 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice [PDF]

, 2014
Holly M. Brown‐Borg, Sharlene Rakoczy, Joseph Wonderlich, Vanessa Armstrong, Lalida Rojanathammanee   +4 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Comparison of growth hormone stimulation tests in prepubertal children with short stature according to response to growth hormone replacement [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose Growth hormone (GH) stimulation tests are essential tools for diagnosing GH deficiency (GHD). We aimed to compare L-dopa, insulin, and arginine-induced stimulation tests based on response to GH replacement.
Seong Hwan Chang, Chan Jong Kim
doaj   +1 more source

Growth Hormone Alters the Glutathione S-Transferase and Mitochondrial Thioredoxin Systems in Long-Living Ames Dwarf Mice [PDF]

, 2013
Lalida Rojanathammanee, S. Rakoczy, Holly M. Brown‐Borg   +2 more
openalex   +1 more source