Results 241 to 250 of about 5,753,417 (283)

Growth hormone response to growth hormone releasing hormone in depression and schizophrenia

Psychiatry Research, 1990
Growth hormone releasing hormone, a 44-amino acid peptide (GHRH-44), was administered (1 micrograms/kg i.v.) to 6 normal controls, 10 schizophrenic subjects, and 7 depressed subjects. A significantly lower growth hormone (GH) response was found in the schizophrenic and depressed groups.
Andrew R Hoffman, J G Csernansky
exaly   +3 more sources

The Therapeutic Use of Growth-Hormone-Releasing Hormone

Journal of Pediatric Endocrinology and Metabolism, 1993
As a significant number of children with growth hormone deficiency have been shown to be able to respond to GHRH with a rise in serum growth hormone (GH) levels, GHRH has been used to treat such children with varying success. GHRH has been given subcutaneously (SC) in GH deficient children to improve growth in dose frequencies of daily, twice daily ...
openaire   +3 more sources

Growth Hormone Releasing Hormone and Growth Hormone Releasing Hormone-Related Peptide in the Testis

1998
Growth hormone releasing hormone (GHRH) is a peptide synthesized in the cell bodies of neurosecretory neurons in the ventromedial and arcuate nuclei of the hypothalamus. When stimulated, GHRH travels down the axons of these neurons and is released into the hypophyseal portal circulation. GHRH binds to receptors on somatotrophs in the anterior pituitary,
K. K. Samaddar, T. M. Todoran, O. Hirsch Pescovitz   +2 more
openaire   +1 more source

Growth Hormone Release in Response to Growth Hormone-Releasing Hormone in Term and Preterm Neonates

Biology of the Neonate, 2009
The growth hormone response to a single intravenous dose of human growth hormone-releasing hormone (GHRH) was examined in 23 healthy neonates (12 term and 11 preterm) aged 2–4 days. There were no significant increases in growth hormone concentrations at any point in time studied following GHRH administration in either group of new-borns. The mean basal
R, Lanes, C, Nieto, C, Bruguera, G, Moncada, L A, Moret, F, Lifshitz   +5 more
openaire   +2 more sources

Interactions of Growth Hormone Secretagogues and Growth Hormone-Releasing Hormone/Somatostatin

Endocrine, 2001
The class of novel synthetic compounds termed growth hormone secretagogues (GHSs) act in the hypothalamus through, as yet, unknown pathways. We performed physiologic and histochemical studies to further understand how the GHS system interacts with the well-established somatostatin (SRIF)/growth hormone-releasing hormone (GHRH) neuroendocrine system for
G S, Tannenbaum, C Y, Bowers
openaire   +2 more sources

Growth Hormone Releasing Hormone

1999
Growth hormone (GH) synthesis and release is regulated by two hypothalamic peptides: somatostatin, which inhibits GH secretion, and growth hormone-releasing hormone (GHRH), which stimulates its release. Although somatostatin was the first to be identified in 1973 (1), the presence of a hypothalamic GH stimulating substance had been predicted in 1960 ...
Paul L. Hofman, O. H. Pescovitz
openaire   +1 more source

Sex differences in growth hormone response to growth hormone-releasing hormone

Journal of Endocrinological Investigation, 1991
The aim of the present study was to ascertain whether sex differences exist in GH response to GHRH, and the influence that menstrual cycle have on this response. A GHRH test was performed on nine healthy men and ten women on days one and twelve of the menstrual cycle.
P, Benito, L, Avila, M S, Corpas, J A, Jiménez, L, Cacicedo, F, Sánchez Franco   +5 more
openaire   +2 more sources

Growth Hormone Responses to Continuous Infusions of Growth Hormone-Releasing Hormone*

The Journal of Clinical Endocrinology & Metabolism, 1985
The pattern of GH secretion during a continuous 4-h iv infusion of 1 microgram/kg.h GH-releasing hormone (1-44)-NH2 (GHRH-44) or saline was examined in 15 adult men. There was prompt release of GH beginning within 20 min of starting the GHRH-44 infusions, reaching peak GH levels of 43 +/- 11 (+/- SE) ng/ml within 60-90 min.
M C, Gelato, R S, Rittmaster, O H, Pescovitz, M C, Nicoletti, W E, Nixon, R, D'Agata, D L, Loriaux, G R, Merriam   +7 more
openaire   +2 more sources

Growth hormone response to growth hormone-releasing hormone in schizophrenic patients

American Journal of Psychiatry, 1990
Ten schizophrenic patients and five normal control subjects were challenged with growth hormone-releasing hormone in a pilot study investigating growth hormone secretion from the pituitary. The results suggest suprapituitary dysfunction in schizophrenia, but replication in a larger study is needed.
D I, Mayerhoff, J A, Lieberman, C Z, Lemus, S, Pollack, B S, Schneider   +4 more
openaire   +2 more sources

Growth Hormone-Releasing Hormone and Growth Hormone Secretagogues in Normal Aging

Endocrine, 2003
Growth hormone (GH) secretion declines with aging, and parallels between normal aging and the signs and symptoms of adult GH deficiency have led to interest in the potential utility of replacing or stimulating GH to promote physical and psychological function and to prolong the capacity for independent living in older adults.
George R, Merriam, Robert S, Schwartz, Michael V, Vitiello   +2 more
openaire   +2 more sources