BackgroundGrowth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids.
Burcu Ayhan-Sahin +4 more
doaj +2 more sources
Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
doaj +3 more sources
Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease
Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang +6 more
doaj +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Strasburger, Christian J. +12 more
core +1 more source
Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Objective: Diagnosis of central precocious puberty has always been challenging in clinicalpractice. As an important method in the diagnosis of central precocious puberty, luteinizinghormone‐releasing hormone stimulation test is complex and time‐consuming.
Yue‐Qin Xu, Gui‐Mei Li, Yan Li
doaj +1 more source
A secretagogin locus of the mammalian hypothalamus controls stress hormone release [PDF]
This work was supported by the Swedish Research Council (T.Ha., T.Hö.), Hjärnfonden (T.Ha.), the Petrus and Augusta Hedlunds Foundation (T.Ha., T.Hö.), the Novo Nordisk Foundation (T.Ha., T.Hö.), Karolinska Institutet (T.Hö.), the Medical University of ...
Marc Landry +58 more
core +1 more source
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]
There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
core +2 more sources
Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Guimond, S +17 more
core +1 more source
Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty [PDF]
Purpose There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare.
Ah Young Cho +3 more
doaj +1 more source
Effects of human growth hormone on gonadotropin-releasing hormone neurons in mice [PDF]
PurposeRecombinant human growth hormone (rhGH) has been widely used to treat short stature. However, there are some concerns that growth hormone treatment may induce skeletal maturation and early onset of puberty.
Janardhan P. Bhattarai +3 more
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