Results 91 to 100 of about 11,206 (235)

Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

BMC Gastroenterology, 2010
Background Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake.
Engel Christoph, Kloor Matthias, Betz Beate, Kötting Judith, Görgens Heike, Schackert Hans K, Morak Monika, Holinski-Feder Elke, Rahner Nils, Steinke Verena, Novotny Jan, Vodickova Ludmila, Naccarati Alessio, Pardini Barbara, Campa Daniele, Büttner Reinhard, Propping Peter, Försti Asta, Hemminki Kari, Barale Roberto, Vodicka Pavel, Canzian Federico   +21 more
doaj   +1 more source

Ghrelin: Ghrelin as a Regulatory Peptide in Growth Hormone Secretion [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Ghrelin is a type of growth hormone (GH) secretagogue that stimulates the release of GH. It is a first hormone linking gastrointestinal-pituitary axis.
Nazli Khatib, Shilpa Gaidhane, Abhay M Gaidhane, Mahanaaz Khatib, Padam Simkhada, Dilip Gode, Quazi Syed Zahiruddin   +6 more
doaj   +1 more source

Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley   +1 more source

Ghrelin and Growth Hormone Secretagogue Receptor Expression in Mice during Aging [PDF]

Endocrinology, 2007
In well-nourished humans, GH and IGF-I decline during aging, and the responsiveness of the GH axis to exogenous ghrelin is attenuated with age. Intriguingly, the GH/IGF-I axis is rejuvenated by chronic treatment with the ghrelin mimetic MK-0677, resulting in improvements in body composition, suggesting that frail elderly subjects might benefit from ...
Yuxiang, Sun, Jose Manuel, Garcia, Roy G, Smith   +2 more
openaire   +2 more sources

Real‐world incidence and risk factors of level 3 (severe) hypoglycaemia in adults with type 1 or 2 diabetes (iNPHORM, United States)

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 675-690, January 2026.
Abstract Aims Level 3 (severe) hypoglycaemia is a serious, yet preventable, complication of insulin‐ or secretagogue‐treated diabetes. However, real‐world insight into its incidence and risk factors remains limited. We analysed data from the iNPHORM study to address this gap.
Alexandria Ratzki‐Leewing, Jason E. Black, Jasminder Bhatti, Bridget L. Ryan, Guangyong Zou, Yu Kuei Lin, Shuo J. Huang, Rozalina G. McCoy, Stewart B. Harris   +8 more
wiley   +1 more source

Supplementary Figure S1A-C from The Neuromedin U-Growth Hormone Secretagogue Receptor 1b/Neurotensin Receptor 1 Oncogenic Signaling Pathway as a Therapeutic Target for Lung Cancer [PDF]

, 2023
Koji Takahashi, Chiyuki Furukawa, Atsushi Takano, Nobuhisa Ishikawa, Tatsuya Kato, Satoshi Hayama, Chie Suzuki, Wataru Yasui, Kouki Inai, Saburo Sone, Tomoo Ito, Hitoshi Nishimura, Eiju Tsuchiya, Yusuke Nakamura, Yataro Daigo   +14 more
openalex   +1 more source

The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery

Frontiers in Genetics, 2021
Type 2 diabetes mellitus (T2DM) is one of the most prominent and socially significant problems. The present study aimed to identify the mechanisms of interaction of critical regulators of carbohydrate metabolism using bioinformatics and experimental ...
Daria Skuratovskaia, Maria Vulf, Nataliya Chasovskikh, Aleksandra Komar, Elena Kirienkova, Egor Shunkin, Pavel Zatolokin, Larisa Litvinova   +7 more
doaj   +1 more source

Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors [PDF]

Molecular Endocrinology, 1997
GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides, GH releasing hormone (GHRH) and somatostatin, via their engagement with specific cell surface receptors on the anterior pituitary somatotroph. In addition, GH-releasing peptides, such as GHRP-6 and the nonpeptide mimetics, L-692,429 and MK-0677, stimulate GH ...
K K, McKee, O C, Palyha, S D, Feighner, D L, Hreniuk, C P, Tan, M S, Phillips, R G, Smith, L H, Van der Ploeg, A D, Howard   +8 more
openaire   +2 more sources

Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
Naira da Silva Mansano, Calvin Vinh Lieu, Alfonso Abizaid   +2 more
wiley   +1 more source

Ghrelin Facilitates GLUT2-, SGLT1- and SGLT2-mediated Intestinal Glucose Transport in Goldfish (Carassius auratus) [PDF]

, 2017
Glucose homeostasis is an important biological process that involves a variety of regulatory mechanisms. This study aimed to determine whether ghrelin, a multifunctional gut-brain hormone, modulates intestinal glucose transport in goldfish (Carassius ...
Bertucci, Juan I., Blanco Imperiali, Ayelén M., Delgado Saavedra, María Jesús, Ramesh, Naresh, Unniappan, Suraj, Valenciano González, Ana Isabel   +5 more
core   +4 more sources