Results 91 to 100 of about 60,269 (268)

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, EarlyView.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

Effect of unacylated ghrelin on peripheral nerve regeneration

European Journal of Histochemistry, 2021
Ghrelin is a circulating peptide hormone released by enteroendocrine cells of the gastrointestinal tract as two forms, acylated and unacylated. Acylated ghrelin (AG) binds to the growth hormone secretagogue receptor 1a (GHSR1a), thus stimulating food ...
Giulia Ronchi, Pierluigi Tos, Elia Angelino, Luisa Muratori, Simone Reano, Nicoletta Filigheddu, Andrea Graziani, Stefano Geuna, Stefania Raimondo   +8 more
doaj   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Plasma LEAP2 concentration is associated with energy intake and postprandial insulin increase depending on meal size but not weight status in men

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4427-4435, August 2025.
Abstract Aims While LEAP2 is increasingly recognized as an appetite‐regulating hormone, its role in meal regulation and the dynamics of postprandial LEAP2 concentrations remain poorly understood in humans. The aim of the study was to (1) assess postprandial LEAP2 concentrations following a recommended‐energy breakfast, exploring potential association ...
María F. Andreoli, Pablo N. De Francesco, Olga E. Titova, Mario Perello, Helgi B. Schiöth   +4 more
wiley   +1 more source

Ghrelin and Growth Hormone Secretagogue Receptor Expression in Mice during Aging [PDF]

Endocrinology, 2007
In well-nourished humans, GH and IGF-I decline during aging, and the responsiveness of the GH axis to exogenous ghrelin is attenuated with age. Intriguingly, the GH/IGF-I axis is rejuvenated by chronic treatment with the ghrelin mimetic MK-0677, resulting in improvements in body composition, suggesting that frail elderly subjects might benefit from ...
Yuxiang Sun, Roy G. Smith, Jose M. Garcia   +2 more
openaire   +3 more sources

Biological, Physiological, and Pharmacological Aspects of Ghrelin

Journal of Pharmacological Sciences, 2006
.: Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor, functions as a somatotrophic and orexigenic signal from the stomach.
Hiroshi Hosoda, Masayasu Kojima, Kenji Kangawa   +2 more
doaj  

The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond

IBRO Neuroscience Reports, 2022
Ghrelin is a stomach-derived peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) and displays a plethora of neuroendocrine, metabolic, autonomic and behavioral actions.
Mario Perelló, María P. Cornejo, Pablo N. De Francesco, Gimena Fernandez, Laurent Gautron, Lesly S. Valdivia   +5 more
doaj  

Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

BMC Gastroenterology, 2010
Background Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake.
Engel Christoph, Kloor Matthias, Betz Beate, Kötting Judith, Görgens Heike, Schackert Hans K, Morak Monika, Holinski-Feder Elke, Rahner Nils, Steinke Verena, Novotny Jan, Vodickova Ludmila, Naccarati Alessio, Pardini Barbara, Campa Daniele, Büttner Reinhard, Propping Peter, Försti Asta, Hemminki Kari, Barale Roberto, Vodicka Pavel, Canzian Federico   +21 more
doaj   +1 more source

Ghrelin drives GH secretion during fasting in man [PDF]

, 2002
OBJECTIVES: In humans, fasting leads to elevated serum GH concentrations. Traditionally, changes in hypothalamic GH-releasing hormone and somatostatin release are considered as the main mechanisms that induce this elevated GH ...
Bidlingmaier, M. (Martin), Ghigo, E. (Ezio), Hofland, L.J. (Leo), Janssen, J.A.M.J.L. (Joop), Koetsveld, P.M. (Peter) van, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der, Muller, A.F. (Alex), Strasburger, C.J.   +8 more
core   +1 more source

The effect of lyophilised oral faecal microbial transplantation on functional outcomes in dogs with diabetes mellitus

Journal of Small Animal Practice, EarlyView.
Objectives We aimed to determine if oral faecal microbiota transplantation improves indices of glycaemic control, changes the faecal dysbiosis indices, alters faecal short‐chain fatty acid and bile acid profiles and increases serum glucagon‐like‐peptide 1 concentrations in diabetic dogs.
R. Brown, P. Barko, J. D. J. Ruiz Romero, D. A. Williams, A. Gochenauer, J. Nguyen‐Edquilang, J. S. Suchodolski, R. Pilla, H. Ganz, N. Lopez‐Villalobos, A. Gal   +10 more
wiley   +1 more source