Results 101 to 110 of about 6,273,650 (192)

Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and monocytes [PDF]

, 2013
Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and ...
David Stensel (1257075), Charlotte Coombs (7247834), Megan Clark (7247831), Nicolette Bishop (1255977), Sean Miller (218704), Harumi Hayashida (7242104)   +5 more
core   +3 more sources

The pentapeptide RM-131 promotes food intake and adiposity in wildtype mice but not in mice lacking the ghrelin receptor

Frontiers in Nutrition, 2015
The gastrointestinal peptide hormone ghrelin is the endogenous ligand of the growth hormone secretagogue receptor (GHSR, a.k.a. ghrelin receptor, GHR). Currently, ghrelin is the only circulating peripheral hormone with the ability to promote a positive ...
Katrin eFischer, Brian eFinan, Christoffer eClemmensen, Lex H.T. van der Ploeg, Matthias H. Tschöp, Timo D. Müller   +5 more
doaj   +1 more source

Stress-induced GHS-R1a expression in medial prefrontal cortical neurons promotes vulnerability to anxiety in mice

Communications Biology
The neural basis of anxiety is unclear, which hinders the treatment of anxiety disorders. Here, we found that αCaMKII+ neurons in the medial prefrontal cortex (mPFCαCaMKII+) responded to stressors with increased activity both under physiological ...
Liu Yang, Meng Zhang, Xiaomin Sun, Anqi Du, Jiajia Jia, Nan Li, Gonghui Hu, Yingchang Lu, Sihan Wang, Jingsai Zhang, Wenjie Chen, Hanbing Yu, Yu Zhou   +12 more
doaj   +1 more source

Molecular cloning and expression characteristics of ghrl and ghsr genes in bighead carp (Hypophthalmichthys nobilis)

Aquaculture and Fisheries
Ghrelin (ghrl) and its receptor gene ghsr (growth hormone secretagogue receptor) regulate numerous physiological functions, including growth hormone secretion and food intake.
Pan Wang, Jianjun Fu, Mingkun Luo, Xiulan Shi, Wenbin Zhu, Lanmei Wang, Shichang Shu, Zaijie Dong   +7 more
doaj   +1 more source

Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist. [PDF]

Biomolecules, 2022
Wang CH, Tseng CY, Hsu WL, Tzen JTC.
europepmc   +1 more source

Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. [PDF]

J Neuroendocrinol, 2023
Perelló M, Dickson SL, Zigman JM, Leggio L, Ghrelin Nomenclature Consensus Group.   +4 more
europepmc   +1 more source

Structure−Function Studies on the New Growth Hormone-Releasing Peptide, Ghrelin:  Minimal Sequence of Ghrelin Necessary for Activation of Growth Hormone Secretagogue Receptor 1a^⊥

, 2016
The recently discovered growth hormone secretagogue, ghrelin, is a potent agonist at the human growth hormone secretagogue receptor 1a (hGHSR1a). To elucidate structural features of this peptide necessary for efficient binding to and activation of the ...
Lex H. Y. Van der Ploeg (3010629), Maria A. Bednarek (1523764), Vivien A. Warren (1884853), Donna L. Hreniuk (3010632), James V. Heck (2672827), Sheng-Shung Pong (3010641), Maria V. Silva (3010638), Scott D. Feighner (3010635), Karen Kulju McKee (3010626), Andrew D. Howard (1792957)   +9 more
core   +1 more source

Immunolocalization of Ghrelin and Its Functional Receptor, the Type 1a Growth Hormone Secretagogue Receptor, in the Cyclic Human Ovary

, 2003
Ghrelin is a novel 28-amino acid peptide identified as the endogenous ligand for the GH secretagogue receptor (GHS-R). Besides its hallmark central neuroendocrine effects in the control of GH secretion and food intake, an unexpected reproductive facet of
Chopin, Lisa K., Herington, Adrian C., L. K. Chopin, Casanueva, Felipe F., Dieguez, Carlos, C. Diéguez, Barreiro, M. Luz, F. Gaytan, Tena-Sempere, Manuel, L. Pinilla, Aguilar, Enrique, Gaytan, Felice, Morales, Concepcion, A. C. Herington, Pinilla, Leonor, M. Tena-Sempere, F. F. Casanueva, E. Aguilar, M. L. Barreiro, C. Morales   +19 more
core   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

, 2017
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co ...
Indarto, Dono, Izawa, Masao
core  

Neuronal ablation of GHSR mitigates diet-induced depression and memory impairment via AMPK-autophagy signaling-mediated inflammation

Frontiers in Immunology
Obesity is associated with chronic inflammation in the central nervous system (CNS), and neuroinflammation has been shown to have detrimental effects on mood and cognition.
Hongying Wang, Hongying Wang, Zheng Shen, Chia-Shan Wu, Pengfei Ji, Ji Yeon Noh, Cédric G. Geoffroy, Sunja Kim, David Threadgill, David Threadgill, David Threadgill, Jianrong Li, Yu Zhou, Xiaoqiu Xiao, Hui Zheng, Yuxiang Sun   +15 more
doaj   +1 more source