Results 101 to 110 of about 10,555 (248)

Abstract Conformer Space

Helvetica Chimica Acta, Volume 108, Issue 7, July 2025.
Proteins are intrinsically flexible and thus require an ensemble description. In abstract conformer space, ensemble diversity is easier to assess and the required ensemble size can be established. Abstract Pairwise distance root mean square deviation defines a hyperspace where conformers with similar shape reside close to each other.
Gunnar Jeschke
wiley   +1 more source

Ghrelin; The Renown Hormone [PDF]

, 2006
Ghrelin , a 28 amino acid gastric peptide, was found to be a potent releaser of GH and in addition, actively participate in controlling energy balance and the regulation of food intake. Specifically, plasma ghrelin originates in the oxyntic gland where A-
H. Murat Bilgin
core  

Endocrine factors in the hypothalamic regulation of food intake in females: a review of the physiological roles and interactions of ghrelin, leptin, thyroid hormones, oestrogen and insulin [PDF]

, 2011
Controlling energy homeostasis involves modulating the desire to eat and regulating energy expenditure. The controlling machinery includes a complex interplay of hormones secreted at various peripheral endocrine endpoints, such as the gastrointestinal ...
Bartha, Tibor, Frenyó, Vilmos László, Goszleth, Gréta, Győrffy, Andrea, Kiss, Dávid Sándor, Scalise, Johnson, Trudy, Somogyi, Virág, Zsarnovszky, Attila   +7 more
core   +1 more source

Arrestin‐centred interactions at the membrane and their conformational determinants

British Journal of Pharmacology, Volume 182, Issue 14, Page 3135-3150, July 2025.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals   +3 more
wiley   +1 more source

Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat [PDF]

Endocrinology, 1997
Synthetic GH secretagogues (GHSs) act via a receptor (GHS-R) distinct from that for GH-releasing hormone (GHRH). We have studied the hypothalamic expression and regulation of this receptor by in situ hybridization using a homologous riboprobe for rat GHS-R.
Gregory B. Thomas, Gregory B. Thomas, Pamela A. Bennett, Pamela A. Bennett, Scott D. Feighner, Scott D. Feighner, Lex H.T. Van der Ploeg, Lex H.T. Van der Ploeg, Roy G. Smith, Roy G. Smith, Iain C. A. F. Robinson, Iain C. A. F. Robinson, Andrew D. Howard, Andrew D. Howard   +13 more
openaire   +3 more sources

The role of ghrelin in anorexia nervosa [PDF]

, 2018
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the stomach, is the only known peripherally produced and centrally acting peptide that stimulates food intake and therefore attracted a lot of attention with one major ...
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Expression pattern of the fused in sarcoma gene and its contextual influence on the density-specific response of the growth hormone/insulin-like growth factor 1 axis in zig-zag eels (Mastacembelus armatus)

Frontiers in Marine Science
The fused in sarcoma (FUS) protein is a DNA/RNA binding protein from the ten-eleven translocation protein family that is associated with neurodegeneration, and it has been shown to promote cell proliferation through the growth hormone/insulin-like growth
Lingzhan Xue, Yu Gao, Songpei Zhang, Manxin Weng, Manxin Weng, Gaoxiong Zeng, Jiajia Chen, Mengxiang Liao, Sayyed Mohammad Hadi Alavi, Yann Guiguen   +9 more
doaj   +1 more source

Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice

Frontiers in Cellular Neuroscience, 2017
The antero-ventral periventricular zone (AVPV) and medial preoptic area (MPOA) have been recognized as gonadal hormone receptive regions of the rodent brain that—via wiring to gonadotropin-releasing hormone (GnRH) neurons—contribute to orchestration of ...
Csaba Vastagh, Zsolt Liposits, Zsolt Liposits   +2 more
doaj   +1 more source

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin. [PDF]

PLoS ONE, 2015
The peptide hormone ghrelin activates the growth hormone secretagogue receptor 1a, also known as the ghrelin receptor. This 28-residue peptide is acylated at Ser3 and is the only peptide hormone in the human body that is lipid-modified by an octanoyl ...
Gerrit Vortmeier, Stephanie H DeLuca, Sylvia Els-Heindl, Constance Chollet, Holger A Scheidt, Annette G Beck-Sickinger, Jens Meiler, Daniel Huster   +7 more
doaj   +1 more source

Predictors of Mortality in Patients With Multiple Endocrine Neoplasia Type 1

Clinical Endocrinology, Volume 103, Issue 1, Page 50-56, July 2025.
SUMMARY Objective Multiple Endocrine Neoplasia Type 1 (MEN 1) is an autosomal dominant disease predisposing to hyperplasia and neoplasia in diverse endocrine tissues. Patients typically present with endocrine abnormalities before the age of 30 years and have reduced life expectancy.
Jasmine J. Zhu, John R Burgess
wiley   +1 more source