Results 101 to 110 of about 60,269 (268)

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice [PDF]

, 2016
The major ghrelin forms, acylated ghrelin and des-acylated ghrelin, are novel gastrointestinal hormones. Moreover, emerging evidence indicates that these peptides may have other functions including neuro- and vaso-protection.
Andrews, Zane B., Austin, Victoria, Barsby, Tom, Chin, Kai Yee, Ku, Jacqueline M., Miller, Alyson A., Spencer, Sarah J., Taher, Mohammadali, Wong, Connie H.Y.   +8 more
core   +1 more source

Somatostatin modulation of initial fusion pores in Ca2+‐triggered exocytosis from mouse chromaffin cells

The Journal of Physiology, EarlyView.
Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley   +1 more source

Ghrelin: Ghrelin as a Regulatory Peptide in Growth Hormone Secretion [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Ghrelin is a type of growth hormone (GH) secretagogue that stimulates the release of GH. It is a first hormone linking gastrointestinal-pituitary axis.
Nazli Khatib, Shilpa Gaidhane, Abhay M Gaidhane, Mahanaaz Khatib, Padam Simkhada, Dilip Gode, Quazi Syed Zahiruddin   +6 more
doaj   +1 more source

The Links of Ghrelin to Incretins, Insulin, Glucagon, and Leptin After Bariatric Surgery

Frontiers in Genetics, 2021
Type 2 diabetes mellitus (T2DM) is one of the most prominent and socially significant problems. The present study aimed to identify the mechanisms of interaction of critical regulators of carbohydrate metabolism using bioinformatics and experimental ...
Daria Skuratovskaia, Maria Vulf, Nataliya Chasovskikh, Aleksandra Komar, Elena Kirienkova, Egor Shunkin, Pavel Zatolokin, Larisa Litvinova   +7 more
doaj   +1 more source

Skeletal Muscle Memory: An Update From the Antidoping Perspective

Drug Testing and Analysis, Volume 17, Issue 7, Page 1063-1070, July 2025.
ABSTRACT This narrative review explores the concept of muscle memory, focusing on the physiological and biochemical mechanisms underlying information retention in skeletal muscle tissue as it relates to antidoping. The discussion encompasses the role of satellite cells (SCs) in myonuclei recruitment, resulting in increased myonuclear density and ...
Claire Traversa
wiley   +1 more source

Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models

Frontiers in Neuroscience, 2013
Ghrelin is an octanoylated peptide hormone, produced by endocrine cells of the stomach, which acts in the brain to increase food intake and body weight.
Aki eUchida, Jeffrey M. Zigman, Mario ePerello   +2 more
doaj   +1 more source

Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons [PDF]

, 2015
The growth hormone secretagogue receptor type 1a (GHSR1a) has the highest constitutive activity of any G protein coupled receptor (GPCR). GHSR1a mediates the action of the hormone ghrelin and, its activation increases transcriptional and electrical ...
Agosti, Agustina Cabral, Altier, Andrews, Andrews, Beedle, Bennett, Cabral, Cabral, Cabral, Cao, Catterall, Chuang, Chuang, Cogger, Cowley, Cui, Daniel Castrogiovanni, Diano, Eduardo Javier López Soto, Emilio Roman Mustafa, Evron, Francina Agosti, Furness, Gamper, Gandini, Heneghan, Holst, Howard, Ikeda, Jesica Raingo, Jiang, Jiang, Kammermeier, Kammermeier, Kern, Keum, Kim, Kineman, Kisilevsky, Kisilevsky, Kitano, Kurrasch, Lauckner, Lipscombe, Liu, Liu, Lopez Soto, Mani, Maria Alejandra Gandini, Mario Perelló, McGirr, Nakazato, Pantel, Paxinos, Petersen, Raingo, Raingo, Rediger, Ribeiro, Ricardo Felix, Sakata, Schaeffer, Schellekens, Shi, Silvia Rodríguez, Suh, Suh, Tong, Uchida, Valentina Martínez Damonte, Wu, Wu, Yang, Yu, Zamponi, Zigman   +76 more
core   +4 more sources

Arrestin‐centred interactions at the membrane and their conformational determinants

British Journal of Pharmacology, Volume 182, Issue 14, Page 3135-3150, July 2025.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals   +3 more
wiley   +1 more source

Hormone and Metabolite Changes associated with Extended Breeding Fasts in Male Northern Elephant Seals (Mirounga Angustirostris) [PDF]

, 2012
We measured metabolic hormones and several key metabolites in breeding adult male northern elephant seals to examine the regulation of fuel metabolism during extended natural fasts of over 3 months associated with high levels of energy expenditure. Males
Costa, Daniel P., Crocker, Daniel E., Houser, Dorian S., Ortiz, Rudy M., Webb, Paul M.   +4 more
core   +1 more source

Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents. [PDF]

, 2007
Administration of ghrelin, an endogenous ligand for the growth hormone secretagogue receptor 1a (GHSR 1a), induces potent stimulating effects on GH secretion and food intake.
Bluet-Pajot, Marie-Thérèse, Epelbaum, Jacques, Longchamps, Romaine, Zizzari, Philippe   +3 more
core   +4 more sources