Results 121 to 130 of about 10,555 (248)

Therapeutic applications of ghrelin agonists in the treatment of gastroparesis [PDF]

, 2015
There remains an unmet need for effective pharmacologic treatments for gastroparesis. Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor and has been shown to regulate energy homeostasis and exert prokinetic effects on ...
Shin, Andrea, Wo, John M.
core   +1 more source

Growth Hormone (GH)-Releasing Hormone (GHRH) and the GH Secretagogue (GHS), L692,585, Differentially Modulate Rat Pituitary GHS Receptor and GHRH Receptor Messenger Ribonucleic Acid Levels [PDF]

, 1999
Rhonda D. Kineman
openalex   +1 more source

Pathophysiology of acute experimental pancreatitis: Lessons from genetically engineered animal models and new molecular approaches [PDF]

, 2005
The incidence of acute pancreatitis is growing and worldwide population-based studies report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and associated with histological changes of necrotizing pancreatitis. There is still
Anne Barbara Tietz, Arnush M, Bhagat L, Bhatia M, Bhatia M, Bockman DE, Burkhard Göke, Claus Schäfer, Demols A, Ebert MP, Frossard JL, Gardner JD, Gerard C, Grady T, Grisham M, Gu D, Gukovskaya AS, Gukovsky I, Hahm KB, Halangk W, Halangk W, Korc M, Lee MS, Leser HG, Massague J, Meda P, Norman J, Ohnishi H, Ohnishi H, Ohnishi H, Roberts AB, Saluja A, Schafer C, Schafer C, Schmid RM, Song AM, Steinle A, Van Acker GJD, Vogelmann R   +38 more
core   +1 more source

The expression and function of growth hormone secretagogue receptor in immune cells: A current perspective. [PDF]

Exp Biol Med (Maywood), 2022
Noh JY, Herrera M, Patil BS, Tan XD, Wright GA, Sun Y.   +5 more
europepmc   +1 more source

Ghrelin induces clock gene expression in the liver of goldfish in vitro via protein kinase C and protein kinase A pathways [PDF]

, 2017
The liver is the most important link between the circadian system and metabolism. As a food-entrainable oscillator, the hepatic clock needs to be entrained by food-related signals.
Alonso Gómez, Ángel Luis, Blanco Imperiali, Ayelén M., Delgado Saavedra, María Jesús, Isorna Alonso, Esther, Kah, Olivier, Sánchez Bretaño, Aída   +5 more
core   +2 more sources

Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus.

PLoS ONE, 2010
BackgroundGhrelin targets the arcuate nucleus, from where growth hormone releasing hormone (GHRH) neurones trigger GH secretion. This hypothalamic nucleus also contains neuropeptide Y (NPY) neurons which play a master role in the effect of ghrelin on ...
Guillaume Osterstock, Pauline Escobar, Violeta Mitutsova, Laurie-Anne Gouty-Colomer, Pierre Fontanaud, François Molino, Jean-Alain Fehrentz, Danielle Carmignac, Jean Martinez, Nathalie C Guerineau, Iain C A F Robinson, Patrice Mollard, Pierre-François Méry   +12 more
doaj   +1 more source

Establishment of a Cell Line Stably Expressing the Growth Hormone Secretagogue Receptor to Identify Crocin as a Ghrelin Agonist. [PDF]

Biomolecules, 2022
Wang CH, Tseng CY, Hsu WL, Tzen JTC.
europepmc   +1 more source

The Expression of the Growth Hormone Secretagogue Receptor Ligand Ghrelin in Normal and Abnormal Human Pituitary and Other Neuroendocrine Tumors1 [PDF]

, 2001
Márta Korbonits, Stephen A. Bustin, Masayasu Kojima, Suzanne Jordan, Eric F. Adams, David Lowe, Kenji Kangawa, Ashley Grossman   +7 more
openalex   +1 more source

Stress-induced GHS-R1a expression in medial prefrontal cortical neurons promotes vulnerability to anxiety in mice

Communications Biology
The neural basis of anxiety is unclear, which hinders the treatment of anxiety disorders. Here, we found that αCaMKII+ neurons in the medial prefrontal cortex (mPFCαCaMKII+) responded to stressors with increased activity both under physiological ...
Liu Yang, Meng Zhang, Xiaomin Sun, Anqi Du, Jiajia Jia, Nan Li, Gonghui Hu, Yingchang Lu, Sihan Wang, Jingsai Zhang, Wenjie Chen, Hanbing Yu, Yu Zhou   +12 more
doaj   +1 more source

Ghrelin and Growth Hormone (GH) Secretagogues Potentiate GH-Releasing Hormone (GHRH)-Induced Cyclic Adenosine 3′,5′-Monophosphate Production in Cells Expressing Transfected GHRH and GH Secretagogue Receptors [PDF]

, 2002
Shane R. Cunha, Kelly E. Mayo
openalex   +1 more source