Results 121 to 130 of about 60,269 (268)

Acetylcholine regulates ghrelin secretion in humans [PDF]

, 2004
Ghrelin secretion has been reportedly increased by fasting and energy restriction but decreased by food intake, glucose, insulin, and somatostatin. However, its regulation is still far from clarified.
Aart Jan van der Lely, Andrea Benso, Ariyasu, Arosio, Barkan, Batterham, Bellone, Broglio, Broglio, Broglio, Broglio, Broglio, Caixas, Carlotta Gauna, Chey, Cohen, Cristina Gottero, Cummings, Cummings, Date, Date, Emanuela Arvat, Espelund, Ezio Ghigo, Fabio Broglio, Flanagan, Flavia Prodam, Ghigo, Ghigo, Gilon, Giustina, Gnanapavan, Haqq, Haqq, Kojima, Lee, Leo Hofland, Lucidi, Masuda, Mohlig, Muccioli, Muller, Nagaya, Nakagawa, Norrelund, Patel, Peter Van Koetsveld, Prodam, Rigamonti, Saad, Schaller, Shiiya, Shimada, Silvia Destefanis, Smith, Sugino, Sun, Tolle, Toshinai, Williams, Yoshihara   +60 more
core   +2 more sources

Efficacy and safety of imeglimin add‐on to DPP‐4 inhibitor therapy in Japanese patients with type 2 diabetes mellitus: An interim analysis of the randomised, double‐blind FAMILIAR trial

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3212-3222, June 2025.
Abstract Aims The ongoing FAMILIAR trial aims to provide evidence for clinical decision‐making and offer a novel treatment paradigm in type 2 diabetes mellitus (T2DM) management. The interim findings of FAMILIAR through Week 24 are reported. Materials and Methods FAMILIAR is a multicentre, randomised, double‐blind study comparing the efficacy and ...
Kohei Kaku, Masashi Shimoda, Takeshi Osonoi, Masahiro Iwamoto, Hideaki Kaneto   +4 more
wiley   +1 more source

Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice

Frontiers in Cellular Neuroscience, 2017
The antero-ventral periventricular zone (AVPV) and medial preoptic area (MPOA) have been recognized as gonadal hormone receptive regions of the rodent brain that—via wiring to gonadotropin-releasing hormone (GnRH) neurons—contribute to orchestration of ...
Csaba Vastagh, Zsolt Liposits, Zsolt Liposits   +2 more
doaj   +1 more source

Endocrine factors in the hypothalamic regulation of food intake in females: a review of the physiological roles and interactions of ghrelin, leptin, thyroid hormones, oestrogen and insulin [PDF]

, 2011
Controlling energy homeostasis involves modulating the desire to eat and regulating energy expenditure. The controlling machinery includes a complex interplay of hormones secreted at various peripheral endocrine endpoints, such as the gastrointestinal ...
Bartha, Tibor, Frenyó, Vilmos László, Goszleth, Gréta, Győrffy, Andrea, Kiss, Dávid Sándor, Scalise, Johnson, Trudy, Somogyi, Virág, Zsarnovszky, Attila   +7 more
core   +1 more source

Hypotheses in light detection by vertebrate ancient opsin in the bird brain

Journal of Neuroendocrinology, Volume 37, Issue 6, June 2025.
Abstract Extra‐retinal photoreception is common across fish and avian species. In birds, the hypothalamus contains non‐visual photoreceptors that detect light and regulate multiple endocrine systems. To date, light‐dependent control of seasonal reproduction is one of the most well‐studied systems that require deep brain photoreception.
Tyler J. Stevenson, Timothy A. Liddle, Simone L. Meddle, Jonathan H. Pérez, Stuart N. Peirson, Russell G. Foster, Gaurav Majumdar   +6 more
wiley   +1 more source

Blockade of the growth hormone (GH) receptor unmasks rapid GH-releasing peptide-6-mediated tissue-specific insulin resistance [PDF]

, 2001
The roles of GH and its receptor (GHR) in metabolic control are not yet fully understood. We studied the roles of GH and the GHR using the GHR antagonist pegvisomant for metabolic control of healthy nonobese men in ...
Bidlingmaier, M. (Martin), Hofland, L.J. (Leo), Janssen, J.A.M.J.L. (Joop), Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der, Muller, A.F. (Alex), Strasburger, C.J.   +6 more
core   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, Volume 297, Issue 6, Page 584-607, June 2025.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

The role of ghrelin in anorexia nervosa [PDF]

, 2018
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the stomach, is the only known peripherally produced and centrally acting peptide that stimulates food intake and therefore attracted a lot of attention with one major ...
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Circulating Immune and Endocrine Markers in Currently Drinking and Abstinent Individuals With Alcohol Use Disorder and Controls

Addiction Biology, Volume 30, Issue 5, May 2025.
Circulating concentrations of BDNF, GLP‐1 and IL‐8 were altered only in abstinent individuals with AUD, likely reflecting greater disease burden and comorbidities compared to current drinkers. ABSTRACT Alcohol use disorder (AUD) is associated with changes in endocrine and immune system function. This study is a secondary analysis aimed at investigating
Ryan E. Tyler, Carlotta Vizioli, Jennifer J. Barb, Mehdi Farokhnia, Lorenzo Leggio   +4 more
wiley   +1 more source

Enhanced metabolic regulation in II/R injury: Comparing multiroute and monoroute enteral nutrition

Journal of Parenteral and Enteral Nutrition, Volume 49, Issue 3, Page 379-388, April 2025.
Abstract Objective This study aimed to compare the effects of enteral nutrition (EN) administered via multiroute or via monoroute on metabolic regulation in intestinal ischemia‐reperfusion (II/R) injury rat model. Methods The rats were divided into sham operation and II/R injury groups. The rats in each group were further treated with either multiroute
Jianfeng Duan, Jiali Liu, Jiawen Chen, Suwan Qian, Xinran Liang, Yanyu Han, Beiyuan Zhang, Tao Gao, Gang Wang, Xiaoyao Li, Wenkui Yu   +10 more
wiley   +1 more source