Results 21 to 30 of about 60,269 (268)

The expression and function of growth hormone secretagogue receptor in immune cells: A current perspective. [PDF]

Exp Biol Med (Maywood), 2022
The orexigenic hormone ghrelin and its receptor, growth hormone secretagogue receptor (GHS-R), have been extensively studied in the last two decades, revealing that ghrelin signaling has important implications in health and disease.
Noh JY, Herrera M, Patil BS, Tan XD, Wright GA, Sun Y.   +5 more
europepmc   +2 more sources

Development and Characterization of an F-labeled Ghrelin Peptidomimetic for Imaging the Cardiac Growth Hormone Secretagogue Receptor [PDF]

Molecular Imaging, 2018
One-third of patients with heart disease develop heart failure, which is diagnosed through imaging and detection of circulating biomarkers. Imaging strategies reveal morphologic and functional changes but fall short of detecting molecular abnormalities ...
Ahmed Abbas MSc, Lihai Yu PhD, Tyler Lalonde BSc, Derek Wu BSc, Jonathan D. Thiessen PhD, Leonard G. Luyt PhD, Savita Dhanvantari PhD   +6 more
doaj   +2 more sources

Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. [PDF]

J Neuroendocrinol, 2023
The stomach‐derived octanoylated peptide ghrelin was discovered in 1999 and recognized as an endogenous agonist of the growth hormone secretagogue receptor (GHSR).
Perelló M, Dickson SL, Zigman JM, Leggio L, Ghrelin Nomenclature Consensus Group.   +4 more
europepmc   +2 more sources

Binding Domain Characterization of Growth Hormone Secretagogue Receptor. [PDF]

J Transl Int Med, 2022
Abstract Background and Objectives Activation of ghrelin receptor growth hormone secretagogue receptor (GHS-R) by endogenous or synthetic ligands amplifies pulsatile release of growth hormone (GH) and enhances food intake, very relevant to development and growth.
Sun Y, Ye X, Kennedy H, Smith AGA, Smith RG.   +4 more
europepmc   +3 more sources

Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and monocytes [PDF]

Brain, behavior, and immunity, 2013
Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and ...
Charlotte Coombs (7247834), David Stensel (1257075), Harumi Hayashida (7242104), Megan Clark (7247831), Nicolette Bishop (1255977), Sean Miller (218704)   +5 more
core   +2 more sources

Growth hormone secretagogue receptor-1a mediates ghrelin's effects on attenuating tumour-induced loss of muscle strength but not muscle mass. [PDF]

J Cachexia Sarcopenia Muscle, 2021
Ghrelin may ameliorate cancer cachexia (CC) by preventing anorexia, muscle, and fat loss. However, the mechanisms mediating these effects are not fully understood.
Liu H, Zang P, Lee II, Anderson B, Christiani A, Strait-Bodey L, Breckheimer BA, Storie M, Tewnion A, Krumm K, Li T, Irwin B, Garcia JM.   +12 more
europepmc   +2 more sources

Contribution of growth hormone secretagogue receptor (GHSR) signaling in the ventral tegmental area (VTA) to the regulation of social motivation in male mice. [PDF]

Transl Psychiatry, 2021
Most psychiatric disorders are characterized by deficits in the ability to interact socially with others. Ghrelin, a hormone normally associated with the regulation of glucose utilization and appetite, is also implicated in the modulation of motivated ...
Park SB, King S, MacDonald D, Wilson A, MacKay H, Woodside B, Abizaid A.   +6 more
europepmc   +2 more sources

Integration of Cell-Free Expression and Solid-State NMR to Investigate the Dynamic Properties of Different Sites of the Growth Hormone Secretagogue Receptor. [PDF]

Front Pharmacol, 2020
Cell-free expression represents an attractive method to produce large quantities of selectively labeled protein for NMR applications. Here, cell-free expression was used to label specific regions of the growth hormone secretagogue receptor (GHSR) with ...
Pacull EM, Sendker F, Bernhard F, Scheidt HA, Schmidt P, Huster D, Krug U.   +6 more
europepmc   +2 more sources

Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors [PDF]

Molecular Endocrinology, 1997
GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides, GH releasing hormone (GHRH) and somatostatin, via their engagement with specific cell surface receptors on the anterior pituitary somatotroph. In addition, GH-releasing peptides, such as GHRP-6 and the nonpeptide mimetics, L-692,429 and MK-0677, stimulate GH ...
Karen K. McKee, Oksana Palyha, Scott D. Feighner, Donna L. Hreniuk, Carina P. Tan, Michael S. Phillips, Roy G. Smith, Lex H.T. Van der Ploeg, Andrew D. Howard   +8 more
  +6 more sources

Immunohistochemical Expression of Growth Hormone Secretagogue Receptor (GSH-R) of Adipose Tissue Macrophagesin Obese Bariatric Patients [PDF]

Revista de Chimie, 2019
Obesity is a major cause of adipose tissue (AT) inflammation. Ghrelin (GHRL), through its growth hormone secretagogue receptor (GHS-R) present on adipose tissue macrophages (ATMs), could modulate AT inflammation.
Daniel Timofte, Veronica Mocanu, Florin Zugun Eloae, Ioana Hristov, Iustina Silivestru Cretu, Viviana Aursulesei, Gheorghe G. Bălan, Bogdan Mihnea Ciuntu, Teodor Oboroceanu, Adrian Tiron, Victor Vlad Costan, Doina Butcovan   +11 more
openalex   +2 more sources