Results 61 to 70 of about 10,555 (248)

The Role of Ghrelin and Growth Hormone Secretagogues Receptor on Rat Adipogenesis [PDF]

open access: yesEndocrinology, 2003
Recent research progress indicates a close link between ghrelin, a natural ligand of GH secretagogues receptor (GHS-R), and both the metabolic balance and body composition. To clarify the involvement of ghrelin and GHS-R in the process of adipogenesis, we measured the expression of GHS-R and peroxisome proliferator-activated receptor gamma 2 (PPAR ...
Choi, Kichoon   +8 more
openaire   +4 more sources

The Ghrelin Receptor (Ghsr) Gene Polymorphism in Indonesian Local Chicken and Crossbreed is Associated with Carcass Traits [PDF]

open access: yes, 2017
Ghrelin receptor (GHSR) gene is candidate gene for growth performance in chicken by modulating growth hormone release from the pituitary by binding to its ligand of ghrelin.
Arief, I. I. (Irma)   +4 more
core   +2 more sources

Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R

open access: yesScientific Reports, 2017
Orexigenic hormone ghrelin and anorexic hormone obestatin are encoded by the same preproghrelin gene. While it is known that ghrelin inhibits glucose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unclear.
Geetali Pradhan   +7 more
doaj   +1 more source

Growth Hormone Secretagogue Receptor Expression in Human Pituitary Tumors1 [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1998
The GH secretagogue (GHS) receptor (GHS-R) has been characterized and cloned. It is a member of a family of seven transmembrane receptors and is closely related to the neurotensin and TRH receptors. To determine the expression of this receptor in normal anterior pituitary and in 24 human pituitary adenomas, we analyzed GHS-R messenger ribonucleic acid (
Beatriz Lopes   +4 more
openaire   +3 more sources

Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]

open access: yes, 2014
Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core   +2 more sources

Effect of Ghrelin on the Cardiovascular System

open access: yesBiology, 2022
Ghrelin, an n-octanoyl-modified 28-amino-acid-peptide, was first discovered in the human and rat stomach as an endogenous ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin-GHS-R1a signaling regulates feeding behavior and energy balance,
Hiroshi Hosoda
doaj   +1 more source

Ghrelin and lipid metabolism: key partners in energy balance [PDF]

open access: yes, 2010
Disclaimer: this is not the definitive version of record of this article. This manuscript has been accepted for publication in "Journal of Molecular Endocrinology", but the version presented here has not yet been copy-edited, formatted or proofed ...
Cordido, Fernando   +6 more
core   +2 more sources

Signal transduction mechanism of the seabream growth hormone secretagogue receptor

open access: yesFEBS Letters, 2004
We have recently cloned the full‐length cDNAs of the two growth hormone secretagogue receptor (GHSR) subtypes from a teleost species, the black seabream (Acanthopagrus schlegeli) [Mol. Cell. Endocrinol. 214 (2004) 81], namely sbGHSR‐1a and sbGHSR‐1b.
Cheng, Christopher H K   +3 more
openaire   +5 more sources

Effects of Astragalus Extract Mixture HT042 on Circulating IGF-1 Level and Growth Hormone Axis in Rats

open access: yesChildren, 2021
Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee   +5 more
doaj   +1 more source

Ghrelin causes hyperphagia and obesity in rats. [PDF]

open access: yes, 2001
Ghrelin, a circulating growth hormone–releasing pep-tide derived from the stomach, stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and the resulting plasma ghre-lin concentration was compared with ...
Abbott, CR   +10 more
core   +1 more source

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