Results 61 to 70 of about 10,555 (248)
The Role of Ghrelin and Growth Hormone Secretagogues Receptor on Rat Adipogenesis [PDF]
Recent research progress indicates a close link between ghrelin, a natural ligand of GH secretagogues receptor (GHS-R), and both the metabolic balance and body composition. To clarify the involvement of ghrelin and GHS-R in the process of adipogenesis, we measured the expression of GHS-R and peroxisome proliferator-activated receptor gamma 2 (PPAR ...
Choi, Kichoon+8 more
openaire +4 more sources
The Ghrelin Receptor (Ghsr) Gene Polymorphism in Indonesian Local Chicken and Crossbreed is Associated with Carcass Traits [PDF]
Ghrelin receptor (GHSR) gene is candidate gene for growth performance in chicken by modulating growth hormone release from the pituitary by binding to its ligand of ghrelin.
Arief, I. I. (Irma)+4 more
core +2 more sources
Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R
Orexigenic hormone ghrelin and anorexic hormone obestatin are encoded by the same preproghrelin gene. While it is known that ghrelin inhibits glucose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unclear.
Geetali Pradhan+7 more
doaj +1 more source
Growth Hormone Secretagogue Receptor Expression in Human Pituitary Tumors1 [PDF]
The GH secretagogue (GHS) receptor (GHS-R) has been characterized and cloned. It is a member of a family of seven transmembrane receptors and is closely related to the neurotensin and TRH receptors. To determine the expression of this receptor in normal anterior pituitary and in 24 human pituitary adenomas, we analyzed GHS-R messenger ribonucleic acid (
Beatriz Lopes+4 more
openaire +3 more sources
Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]
Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core +2 more sources
Effect of Ghrelin on the Cardiovascular System
Ghrelin, an n-octanoyl-modified 28-amino-acid-peptide, was first discovered in the human and rat stomach as an endogenous ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin-GHS-R1a signaling regulates feeding behavior and energy balance,
Hiroshi Hosoda
doaj +1 more source
Ghrelin and lipid metabolism: key partners in energy balance [PDF]
Disclaimer: this is not the definitive version of record of this article. This manuscript has been accepted for publication in "Journal of Molecular Endocrinology", but the version presented here has not yet been copy-edited, formatted or proofed ...
Cordido, Fernando+6 more
core +2 more sources
Signal transduction mechanism of the seabream growth hormone secretagogue receptor
We have recently cloned the full‐length cDNAs of the two growth hormone secretagogue receptor (GHSR) subtypes from a teleost species, the black seabream (Acanthopagrus schlegeli) [Mol. Cell. Endocrinol. 214 (2004) 81], namely sbGHSR‐1a and sbGHSR‐1b.
Cheng, Christopher H K+3 more
openaire +5 more sources
Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee+5 more
doaj +1 more source
Ghrelin causes hyperphagia and obesity in rats. [PDF]
Ghrelin, a circulating growth hormone–releasing pep-tide derived from the stomach, stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and the resulting plasma ghre-lin concentration was compared with ...
Abbott, CR+10 more
core +1 more source