Results 81 to 90 of about 10,555 (248)
Effect of unacylated ghrelin on peripheral nerve regeneration
Ghrelin is a circulating peptide hormone released by enteroendocrine cells of the gastrointestinal tract as two forms, acylated and unacylated. Acylated ghrelin (AG) binds to the growth hormone secretagogue receptor 1a (GHSR1a), thus stimulating food ...
Giulia Ronchi+8 more
doaj +1 more source
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
Ghrelin drives GH secretion during fasting in man [PDF]
OBJECTIVES: In humans, fasting leads to elevated serum GH concentrations. Traditionally, changes in hypothalamic GH-releasing hormone and somatostatin release are considered as the main mechanisms that induce this elevated GH ...
Bidlingmaier, M. (Martin)+8 more
core +1 more source
The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond
Ghrelin is a stomach-derived peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) and displays a plethora of neuroendocrine, metabolic, autonomic and behavioral actions.
Mario Perelló+5 more
doaj
Functional, Nutraceutical and Health Endorsing Perspectives of Saffron
Saffron is generally regarded as safe for human consumption in moderate quantities, its potential adverse effects at higher doses require careful consideration. This review presents a balanced perspective on saffron's medicinal potential and its safe usage, making it a valuable resource for researchers and healthcare professionals.
Tabussam Tufail+4 more
wiley +1 more source
Ghrelin and Growth Hormone Secretagogue Receptor Expression in Mice during Aging [PDF]
In well-nourished humans, GH and IGF-I decline during aging, and the responsiveness of the GH axis to exogenous ghrelin is attenuated with age. Intriguingly, the GH/IGF-I axis is rejuvenated by chronic treatment with the ghrelin mimetic MK-0677, resulting in improvements in body composition, suggesting that frail elderly subjects might benefit from ...
Yuxiang Sun+2 more
openaire +3 more sources
Blockade of the growth hormone (GH) receptor unmasks rapid GH-releasing peptide-6-mediated tissue-specific insulin resistance [PDF]
The roles of GH and its receptor (GHR) in metabolic control are not yet fully understood. We studied the roles of GH and the GHR using the GHR antagonist pegvisomant for metabolic control of healthy nonobese men in ...
Bidlingmaier, M. (Martin)+6 more
core +1 more source
Biological, Physiological, and Pharmacological Aspects of Ghrelin
.: Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor, functions as a somatotrophic and orexigenic signal from the stomach.
Hiroshi Hosoda+2 more
doaj
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian+17 more
wiley +1 more source
Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents. [PDF]
Administration of ghrelin, an endogenous ligand for the growth hormone secretagogue receptor 1a (GHSR 1a), induces potent stimulating effects on GH secretion and food intake.
Bluet-Pajot, Marie-Thérèse+3 more
core +4 more sources