Growth hormone secretagogue receptor

Results 81 to 90 of about 11,206 (235)

Growth Hormone–Releasing Peptides: Investigation of Their Secondary Structure, Thermal Stability, and Model Membrane Interactions

Chirality, Volume 38, Issue 2, February 2026.
Eight growth hormone–releasing peptides were analyzed by electronic circular dichroism spectroscopy, including evaluation of their thermal stability and interactions with model membranes. In the selected case, occurring interactions were successfully described by the density functional theory calculations, revealing how model membranes affected ...
František Králík +4 more
wiley +1 more source

A novel non-peptidic agonist of the ghrelin receptor with orexigenic activity in vivo [PDF]

, 2016
Loss of appetite in the medically ill and ageing populations is a major health problem and a significant symptom in cachexia syndromes, which is the loss of muscle and fat mass. Ghrelin is a gut-derived hormone which can stimulate appetite.
Clarke, Sarah L. +7 more
core +2 more sources

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source

The obestatin receptor (GPR39) is expressed in human adipose tissue and is down-regulated in obesity-associated type 2 diabetes mellitus [PDF]

, 2007
The G protein-coupled receptor 39 (GPR39) has recently been identified as the receptor for obestatin, a peptidic hormone involved in energy homeostasis.
Catalan, V. (Victoria) +8 more
core +1 more source

Safety and effectiveness of tirzepatide during Ramadan fasting: Real‐world evidence from patients with type 2 diabetes in Bangladesh

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1508-1516, February 2026.
Abstract Aims Ramadan fasting poses challenges for patients with type 2 diabetes mellitus (T2DM) due to increased risks of hypoglycemia and metabolic fluctuations. Tirzepatide, a dual GIP/GLP‐1 receptor agonist, has shown marked efficacy in glycemic control and weight reduction.
Muhammad Hafizur Rahman +11 more
wiley +1 more source

Sodium is a negative allosteric regulator of the ghrelin receptor

Cell Reports, 2023
Summary: The functional properties of G protein-coupled receptors (GPCRs) are intimately associated with the different components in their cellular environment.
Guillaume Ferré +8 more
doaj +1 more source

Signal transduction mechanism of the seabream growth hormone secretagogue receptor

FEBS Letters, 2004
We have recently cloned the full‐length cDNAs of the two growth hormone secretagogue receptor (GHSR) subtypes from a teleost species, the black seabream ( Acanthopagrus schlegeli ) [Mol. Cell. Endocrinol. 214 (2004) 81], namely sbGHSR‐1a and sbGHSR‐1b.
Cheng, Christopher H K +3 more
openaire +4 more sources

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components [PDF]

, 2014
G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner.
Agnati, Luigi F +12 more
core +4 more sources

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

American Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 205-214, January 2026.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart +336 more
wiley +1 more source

Molecular characterization of the bovine GHRL gene [PDF]

, 2009
peer reviewedaudience: researcherBovine ghrelin, a 27 amino acid pepticle, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion.
Colinet, Frédéric, Portetelle, Daniel, Renaville, Robert +2 more
core +1 more source

medicine
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hormone
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