Results 61 to 70 of about 5,307 (166)
Laparoscopic resection of small bowel neuroendocrine tumors: A long‐term survival analysis
Abstract Small bowel neuroendocrine tumors (SBNET) are rare neoplasms that often present insidiously and may be associated with mesenteric fibrosis and advanced disease at diagnosis. While open surgery has traditionally been the standard of care, the role of laparoscopic resection in patients with complex SBNET remains under evaluation.
Michal Perets +6 more
wiley +1 more source
Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models
Ghrelin is an octanoylated peptide hormone, produced by endocrine cells of the stomach, which acts in the brain to increase food intake and body weight.
Aki eUchida +2 more
doaj +1 more source
ABSTRACT Background Cancer cachexia is a debilitating syndrome marked by involuntary weight loss resulting from reduced food intake and intricate metabolic reprogramming. Despite its high prevalence, cancer cachexia remains undertreated, with a lack of effective and approved pharmacotherapies.
J. E. Hunt +20 more
wiley +1 more source
The fused in sarcoma (FUS) protein is a DNA/RNA binding protein from the ten-eleven translocation protein family that is associated with neurodegeneration, and it has been shown to promote cell proliferation through the growth hormone/insulin-like growth
Lingzhan Xue +9 more
doaj +1 more source
Altered responses to ghrelin and food cues in AgRP neurons during pregnancy and lactation
Abstract Pregnancy and lactation trigger many metabolic adaptations, including increased food intake to support the energy demands of the growing foetus and then to provide nutrition through milk production after birth. Ghrelin, an orexigenic hormone, activates agouti related peptide (AgRP) neurons in the arcuate nucleus to promote food intake.
C. L. Murrell +4 more
wiley +1 more source
Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice
The antero-ventral periventricular zone (AVPV) and medial preoptic area (MPOA) have been recognized as gonadal hormone receptive regions of the rodent brain that—via wiring to gonadotropin-releasing hormone (GnRH) neurons—contribute to orchestration of ...
Csaba Vastagh +2 more
doaj +1 more source
Abstract Despite the ubiquitous use of monosodium glutamate (MSG) as a food additive, its specific effects on intestinal health and disease remain largely unclear. Here we found mucosal application of MSG induced an upward intestinal short‐circuit current (Isc) in the murine ileum, which was significantly reduced by extracellular Cl−, Na+, and Ca2 ...
Yunxian Wang +4 more
wiley +1 more source
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem +5 more
wiley +1 more source
ABSTRACT Background and Aims This research aimed to assess the effectiveness of high‐intensity interval training (HIIT) and high‐intensity functional training (HIFT) on appetite‐related hormones (Ghrelin, peptide tyrosine–tyrosine (PYY), and glucagon‐like peptide‐1(GLP‐1)), appetite perception, and anthropometric measures in overweight and obese young ...
Vahid Fekri‐Kourabbaslou +2 more
wiley +1 more source
ABSTRACT The melanocortin‐3 receptor (MC3R) and the melanocortin‐4 receptor (MC4R), both expressed in hypothalamic nuclei, are key downstream effectors of leptin signaling and play important roles in energy homeostasis. While pathogenic variants in the MC4R gene represent the most common cause of monogenic obesity, the clinical significance of MC3R ...
Niels Vos +8 more
wiley +1 more source

