Results 11 to 20 of about 1,817,169 (352)
Growth Plate Senescence and Catch-Up Growth [PDF]
, 2011 Longitudinal bone growth is rapid in prenatal and early postnatal life, but then slows with age and eventually ceases. This growth deceleration is caused primarily by a decrease in chondrocyte proliferation, and is associated with other structural, functional, and molecular changes collectively termed growth plate senescence.
Julian C. Lui +2 more
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Growth-inhibiting conditions slow growth plate senescence [PDF]
Journal of Endocrinology, 2010 The mammalian growth plate undergoes programmed senescence during juvenile life, causing skeletal growth to slow with age. We previously found that hypothyroidism in rats slowed both growth plate chondrocyte proliferation and growth plate senescence, suggesting that senescence is not dependent on age per se but rather on chondrocyte proliferation ...
Patricia, Forcinito +5 more
openaire +2 more sources
Applied Sciences, 2021 Allium fistulosum is a perennial plant species grown worldwide belonging to the family Liliaceae. In Korean medicine, it is referred to as Chongbaek (CB), and it is prescribed for symptoms associated with the common cold due to its antipyretic properties.
Jin Ah Ryuk +3 more
doaj +1 more source
Smad4 regulates growth plate matrix production and chondrocyte polarity. [PDF]
, 2017 Smad4 is an intracellular effector of the TGFβ family that has been implicated in Myhre syndrome, a skeletal dysplasia characterized by short stature, brachydactyly and stiff joints.
Alliston, Tamara +4 more
core +3 more sources
A Global Plate Model Including Lithospheric Deformation Along Major Rifts and Orogens Since the Triassic [PDF]
, 2019 Global deep‐time plate motion models have traditionally followed a classical rigid plate approach, even though plate deformation is known to be significant.
Bower, Dan J. +9 more
core +1 more source
eLife, 2019 We respond to concerns expressed by Pacifici and Shore (2019) about a recent paper (Lees-Shepard and Goldhamer, 2018a) in which we reported that the drug palovarotene can have severe side effects in a mouse model of fibrodysplasia ossificans progressiva.
David J Goldhamer, John B Lees-Shepard
doaj +1 more source
Buckling of a growing tissue and the emergence of two-dimensional patterns [PDF]
, 2013 The process of biological growth and the associated generation of residual stress has previously been considered as a driving mechanism for tissue buckling and pattern selection in numerous areas of biology.
Jensen, OE, King, JR, Nelson, MR
core +1 more source
Frontiers in Surgery, 2022 The growth plate is the weakest structure in the skeleton of a child and a frequent site of injury or fracture; physeal injuries represent 15%–30% of all fractures in children.
Luca Basiglini +5 more
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A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion
Frontiers in Materials, 2018 The epiphyseal growth plate is a developmental region responsible for linear bone growth, in which chondrocytes undertake a tightly regulated series of biological processes. Concomitant with the cessation of growth and sexual maturation, the human growth
Katherine A. Staines +4 more
doaj +1 more source
Children, 2021 Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee +5 more
doaj +1 more source