Results 21 to 30 of about 6,474,870 (228)

Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor

open access: yeseLife, 2017
Activating mutations in fibroblast growth factor (FGF) receptor 3 and inactivating mutations in the NPR2 guanylyl cyclase both cause severe short stature, but how these two signaling systems interact to regulate bone growth is poorly understood. Here, we
Leia C Shuhaibar   +13 more
doaj   +1 more source

Effects of Astragalus Extract Mixture HT042 on Circulating IGF-1 Level and Growth Hormone Axis in Rats

open access: yesChildren, 2021
Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee   +5 more
doaj   +1 more source

Roles of Sodium Hydrogen Exchanger (NHE1) and Anion Exchanger (AE2) across Chondrocytes Plasma Membrane during Longitudinal Bone Growth

open access: yesMembranes, 2022
Mammalian long bone growth occurs through endochondral ossification, majorly regulated by the controlled enlargement of chondrocytes at the growth plate (GP). This study aimed to investigate the roles of Na+/H+ (sodium hydrogen exchanger (NHE1)) and HCO3−
Adamu Abdul Abubakar   +8 more
doaj   +1 more source

Ultra-Processed Food Impairs Bone Quality, Increases Marrow Adiposity and Alters Gut Microbiome in Mice

open access: yesFoods, 2021
Ultra processed foods (UPF) consumption is becoming dominant in the global food system, to the point of being the most recent cause of malnutrition. Health outcomes of this diet include obesity and metabolic syndrome; however, its effect on skeletal ...
Tamara Travinsky-Shmul   +8 more
doaj   +1 more source

Effect of Titanium Dioxide Nanoparticles on Parental Oxidative Status and Offspring Skeleton Development and the Protective Role of Portulaca oleracea Seed Extract: Histological and Morphometric Study [PDF]

open access: yesThe Egyptian Journal of Histology
Introduction: Titanium dioxide nanoparticles used in numerous medical and industrial applications. TiO2NPs nanotoxicity is a major health concern.Aim of the Work: The objective of this research was to examine the oxidative status of parental exposed to ...
Fatma El-Demerdash   +4 more
doaj   +1 more source

Hsa_circ_0008870 suppresses bone formation of growth plate through inhibition of miR-185-3p/ MAPK1 axis in idiopathic short stature

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Idiopathic short stature (ISS) is the most common clinical cause of the short stature with an unclear aetiology and a lack of effective treatment. Circular RNAs have been shown to play a significant regulatory role through various signal transduction ...
Zhiwen Wu   +18 more
doaj   +1 more source

Different Effects of Soy and Whey on Linear Bone Growth and Growth Pattern in Young Male Sprague-Dawley Rats

open access: yesFrontiers in Nutrition, 2021
The aim of this investigation was to determine the better protein for supporting optimal linear growth, as the exact composition and benefits of specific dietary proteins in supporting linear growth is unknown.
Meytal Bar-Maisels   +10 more
doaj   +1 more source

Chondroitin sulphate sulphation motif expression in the ontogeny of the intervertebral disc [PDF]

open access: yesEuropean Cells & Materials, 2011
Chondroitin sulphate chains on cell and extracellular matrix proteoglycans play important regulatory roles in developing systems. Specific, developmentally regulated, sulphation motifs within the chondroitin glycosaminoglycan structure may help bind ...
AJ Hayes   +3 more
doaj  

Radiographic Appearance of the Fore Digit and Carpal Joint in the Mule Foal from Birth to 3 Months of Age

open access: yesAnimals, 2023
Few studies have established the normal radiographic anatomical development of the donkey foal and, to date, no data are available for mules. Our aim was thus to evaluate the radiographic development of the fore digit and carpal joint in the mule foal ...
Irene Nocera   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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