Results 11 to 20 of about 839,572 (264)
The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration
Frontiers in Bioengineering and Biotechnology, 2022 Cartilage injury and degeneration are hallmarks of osteoarthritis (OA), the most common joint disease. OA is a major contributor to pain, loss of function, and reduced quality of life.
T. Mark Campbell +11 more
doaj +1 more source
Up IGF-I via high-toughness adaptive hydrogels for remodeling growth plate of children [PDF]
Regenerative Biomaterials, Wenguo Cui, Yiming Zheng
exaly +2 more sources
Applied Sciences, 2021 Allium fistulosum is a perennial plant species grown worldwide belonging to the family Liliaceae. In Korean medicine, it is referred to as Chongbaek (CB), and it is prescribed for symptoms associated with the common cold due to its antipyretic properties.
Jin Ah Ryuk +3 more
doaj +1 more source
RECENT RESEARCH ON THE GROWTH PLATE: Recent insights into the regulation of the growth plate [PDF]
Journal of Molecular Endocrinology, 2014 For most bones, elongation is driven primarily by chondrogenesis at the growth plates. This process results from chondrocyte proliferation, hypertrophy, and extracellular matrix secretion, and it is carefully orchestrated by complex networks of local paracrine factors and modulated by endocrine factors.
Julian C, Lui +2 more
openaire +2 more sources
eLife, 2019 We respond to concerns expressed by Pacifici and Shore (2019) about a recent paper (Lees-Shepard and Goldhamer, 2018a) in which we reported that the drug palovarotene can have severe side effects in a mouse model of fibrodysplasia ossificans progressiva.
David J Goldhamer, John B Lees-Shepard
doaj +1 more source
A Computed Microtomography Method for Understanding Epiphyseal Growth Plate Fusion
Frontiers in Materials, 2018 The epiphyseal growth plate is a developmental region responsible for linear bone growth, in which chondrocytes undertake a tightly regulated series of biological processes. Concomitant with the cessation of growth and sexual maturation, the human growth
Katherine A. Staines +4 more
doaj +1 more source
Frontiers in Surgery, 2022 The growth plate is the weakest structure in the skeleton of a child and a frequent site of injury or fracture; physeal injuries represent 15%–30% of all fractures in children.
Luca Basiglini +5 more
doaj +1 more source
Children, 2021 Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee +5 more
doaj +1 more source
Membranes, 2022 Mammalian long bone growth occurs through endochondral ossification, majorly regulated by the controlled enlargement of chondrocytes at the growth plate (GP). This study aimed to investigate the roles of Na+/H+ (sodium hydrogen exchanger (NHE1)) and HCO3−
Adamu Abdul Abubakar +8 more
doaj +1 more source
eLife, 2017 Activating mutations in fibroblast growth factor (FGF) receptor 3 and inactivating mutations in the NPR2 guanylyl cyclase both cause severe short stature, but how these two signaling systems interact to regulate bone growth is poorly understood. Here, we
Leia C Shuhaibar +13 more
doaj +1 more source