Results 11 to 20 of about 870,777 (309)

Resolving trabecular metaphyseal bone profiles downstream of the growth plate adds value to bone histomorphometry in mouse models

open access: yesFrontiers in Endocrinology, 2023
IntroductionHistomorphometry of rodent metaphyseal trabecular bone, by histology or microCT, is generally restricted to the mature secondary spongiosa, excluding the primary spongiosa nearest the growth plate by imposing an ‘offset’.
P. L. Salmon   +5 more
doaj   +1 more source

Pubertal growth and epiphyseal fusion [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2015
The complex networks of nutritional, cellular, paracrine, and endocrine factors are closely related with pubertal growth and epiphyseal fusion. Important influencing factors include chondrocyte differentiation capacity, multiple molecular pathways active
Kye Shik Shim
doaj   +1 more source

The Hunt Is On! In Pursuit of the Ideal Stem Cell Population for Cartilage Regeneration

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Cartilage injury and degeneration are hallmarks of osteoarthritis (OA), the most common joint disease. OA is a major contributor to pain, loss of function, and reduced quality of life.
T. Mark Campbell   +11 more
doaj   +1 more source

Effect of Allium fistulosum Extracts on the Stimulation of Longitudinal Bone Growth in Animal Modeling Diet-Induced Calcium and Vitamin D Deficiencies

open access: yesApplied Sciences, 2021
Allium fistulosum is a perennial plant species grown worldwide belonging to the family Liliaceae. In Korean medicine, it is referred to as Chongbaek (CB), and it is prescribed for symptoms associated with the common cold due to its antipyretic properties.
Jin Ah Ryuk   +3 more
doaj   +1 more source

RECENT RESEARCH ON THE GROWTH PLATE: Recent insights into the regulation of the growth plate [PDF]

open access: yesJournal of Molecular Endocrinology, 2014
For most bones, elongation is driven primarily by chondrogenesis at the growth plates. This process results from chondrocyte proliferation, hypertrophy, and extracellular matrix secretion, and it is carefully orchestrated by complex networks of local paracrine factors and modulated by endocrine factors.
Julian C, Lui   +2 more
openaire   +2 more sources

The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438 [PDF]

open access: yes, 2007
Long-term use of glucocorticoids (GC) can cause growth retardation in children due to their actions on growth plate chondrocytes. AL-438, a non-steroidal anti-inflammatory agent that acts through the glucocorticoid receptor (GR) retains full anti ...
Farquharson, C   +7 more
core   +1 more source

Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

open access: yeseLife, 2019
We respond to concerns expressed by Pacifici and Shore (2019) about a recent paper (Lees-Shepard and Goldhamer, 2018a) in which we reported that the drug palovarotene can have severe side effects in a mouse model of fibrodysplasia ossificans progressiva.
David J Goldhamer, John B Lees-Shepard
doaj   +1 more source

A Rare Case of Salter-Harris Type I Growth Plate Injury in a Patient Undergoing Limb-Lengthening Procedure

open access: yes, 2023
Growth plate injuries over the distal femur typically occur due to high-energy trauma. It is commonly associated with serious complications such as growth disturbance. Its occurrence in children undergoing limb-lengthening procedures is uncommon.
Mohd Yusof, Nazri   +11 more
core   +1 more source

Analysing and meta-analysing time-series data of microbial growth and gene expression from plate readers

open access: yes, 2021
Responding to change is a fundamental property of life, making time-series data invaluable in biology. For microbes, plate readers are a popular, convenient means to measure growth and also gene expression using fluorescent reporters.
Manzanaro Moreno, Nahuel   +2 more
core   +1 more source

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