Results 61 to 70 of about 870,777 (309)

Osthole: A Coumarin Derivative Assuage Thiram-Induced Tibial Dyschondroplasia by Regulating BMP-2 and RUNX-2 Expressions in Chickens

Antioxidants, 2019
Avian tibial dyschondroplasia affects fast growing broiler chickens accounting for almost 30% of leg ailments in broilers. The present project was designed to assess the efficacy of osthole against avian tibial dyschondroplasia (TD).
Muhammad Waqas, Yaping Wang, Aoyun Li, Hammad Qamar, Wangyuan Yao, Xiaole Tong, Jialu Zhang, Mudassar Iqbal, Khalid Mehmood, Jiakui Li   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: The repair and regeneration of growth plate injuries using tissue engineering techniques remains a challenge due to large bone bridge formation and low chondrogenic efficiency.Methods: In this study, a bilayer drug-loaded microspheres was ...
Lei Qiang, Lei Qiang, Minjie Fan, Yiwei Wang, Yihao Liu, Yihao Liu, Hanjie Zhuang, Ruoyi Guo, Hao Huang, Yulong Ben, Dalin Wang, Xiaoling Wu, Jinwu Wang, Jie Weng, Pengfei Zheng   +14 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Management of foot and ankle injuries in pediatric and adolescent athletes: a narrative review

Orthopedic Research and Reviews, 2018
Laura E Gill,1,2 Kevin E Klingele,1,2 1Department of Orthopedic Surgery, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, USA Abstract: In this review, we
Gill LE, Klingele KE
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Plate growth fitness data

, 2013
Plate growth fitness ...
Queller, David C., Fox, Sara, Strassman, Joan E., David C. Queller (130495), Sara Fox (3257922), Joan E. Strassman (3257919), Hall, David W., David W. Hall (341831)   +7 more
core   +1 more source

The crosstalk between FGF21 and GH leads to weakened GH receptor signaling and IGF1 expression and is associated with growth failure in very preterm infants

Frontiers in Endocrinology, 2023
BackgroundFibroblast growth factor 21 (FGF21) is an essential metabolic regulator that adapts to changes in nutritional status. Severe childhood undernutrition induces elevated FGF21 levels, contributing to growth hormone (GH) resistance and subsequent ...
Jayna N. Mistry, Sanna Silvennoinen, Farasat Zaman, Lars Sävendahl, Katia Mariniello, Charlotte Hall, Sasha R. Howard, Leo Dunkel, Ulla Sankilampi, Leonardo Guasti   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source