Results 101 to 110 of about 5,144 (202)
Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids [PDF]
, 2019 Current clinical diagnosis is typically based on a combination of approaches including clinical examination of the patient, clinical experience, physiologic and/or genetic parameters, high-tech diagnostic medical imaging, and an extended list of ...
Hoste, Eric, Vanden Berghe, Tom
core +2 more sources
Diabetes, Metabolic Syndrome and Obesity, 2020 Si Wen,1,* Zhao-Hua Wang,2,* Cong-Xiao Zhang,1 Ying Yang,1 Qiu-Ling Fan1 1Department of Nephrology, First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Affiliated Dalian Friendship Hospital of Dalian Medical ...
Wen S, Wang ZH, Zhang CX, Yang Y, Fan QL
doaj
Dynamic regulation of cell death signaling [PDF]
There are many ways for a cell to die, but each cell only dies once, causing an inherent variability that results from common triggers activating interconnected signaling networks that diverge at key decision points during cell death initiation ...
Garcia-Saez, A. , Majoul, A.
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Frontiers in Cell and Developmental BiologyBackgroundBone marrow (BM) suppression is the most prevalent dose-limiting side effect of chemotherapy and radiotherapy. Exposure to ionizing radiation (IR) results in acute BM suppression and long-term BM injury.
Lulu Su +10 more
doaj +1 more source
Bioorthogonal Activation of Deep Red Photoredox Catalysis Inducing Pyroptosis [PDF]
The revolutionary impact of photoredox catalytic processes has ignited novel avenues for exploration, empowering us to delve into nature in unprecedented ways and to pioneer innovative biotechnologies for therapy and diagnosis.
Fox, Joseph M +6 more
core +1 more source
Advanced ScienceDrug‐induced liver injury (DILI) is a significant global health issue that poses high mortality and morbidity risks. One commonly observed cause of DILI is acetaminophen (APAP) overdose. GSDME is an effector protein that induces non‐canonical pyroptosis.
Shen‐Xi Ouyang +15 more
doaj +1 more source
Mitochondrial dynamics and pore formation in regulated cell death pathways [PDF]
Mitochondria act as central hubs for cell death signaling. During apoptosis and regulated necrosis (pyroptosis, necroptosis, and ferroptosis), mitochondria undergo drastic changes including membrane permeabilization, fragmentation, and loss of membrane ...
Garcia-Saez, A. , Hohorst, L., Ros, U.
core +2 more sources
Mitoxyperilysis: A Milestone Discovery in the Field of Cell Death
MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
Maochen Li, Yuhan Niu, Pengtao Jiao
wiley +1 more source
Pyroptosis: A Novel Therapeutic Target for Bioactive Compounds in Human Disease Treatment? A Narrative Review [PDF]
Background/Objectives: Bioactive compounds possess the ability to maintain health and improve diseases by regulating inflammation and cell death processes.
Armas Diaz Y +10 more
core +1 more source
American journal of cancer researchPyroptosis, a newly discovered mode of programmed cell death (PCD), is important in the regulation of cancer development. High mobility group box 1 (HMGB1) is a non-histone nuclear protein that is closely related to tumor development and chemotherapy resistance.
Chen-Ying, Fan +7 more
openaire +1 more source