Results 101 to 110 of about 4,201 (162)

Andrographolide Suppresses Influenza A Virus-Induced Pyroptosis via PI3K/AKT-Mediated Caspase-3/GSDME Inactivation. [PDF]

Biomedicines
Yang W, He Q, Sun Z, Zhang X, Li Q, Zhou C, Cui Y, Wei Z, Shi J, Wang C, Jiao Y, Guo L, Xing Y, Wang S.   +13 more
europepmc   +1 more source

GSDME-mediated pyroptosis is essential for the chemotherapeutic effects achieved by combined treatment of temsirolimus and 5-fluorouracil in ovarian carcinoma cells. [PDF]

Am J Transl Res
Chen Z, Ye M, Gu C, Wen N, Wang N, Meng Y.   +5 more
europepmc   +1 more source

Gasdermin E is dispensable for H1N1 influenza virus pathogenesis in mice. [PDF]

Microbiol Spectr
Speaks S, Papa J, McFadden M, Roettger JE, Liu BD, Mohan S, Reznik BM, Leumi S, Cable JM, Forero A, Yount JS.   +10 more
europepmc   +1 more source

Feilike and Its Constituent Licochalcone B Trigger Caspase-3/GSDME-Mediated Pyroptosis in Triple-Negative Breast Cancer via Modulation of the Mutant p53-Calcium/ER Stress-ROS-MAPK Axis. [PDF]

Antioxidants (Basel)
Yang J, Zhao P, Zhou L, Song H, Feng Z, Cui H, Li Y, Qiu J, Hao X.   +8 more
europepmc   +1 more source

Endoplasmic Reticulum-Targeting NIR Cyanine ER800 Nanoparticles Promote Pyroptosis in Triple-Negative Breast Cancer. [PDF]

ACS Appl Mater Interfaces
Yang J, Jiang J, Yang Y, Shen Z, Lin Z, Gao X, Wu W, Ye Z, Gao J, Gao N.   +9 more
europepmc   +1 more source

GSDME-IL-18 pyroptotic axis prevents myosteatosis by expanding tissue-resident macrophages to promote muscle regeneration. [PDF]

J Clin Invest
Cao Q, Liu J, Huang G, Wang SY, Lu GD, Huang Y, Chen YT, Zhang Z, Fu JT, Sun SJ, Chen XF, Zhuang C, Sheng C, Shen FM, Li DJ, Wang P.   +15 more
europepmc   +1 more source

An MRI-visible nanotheranostic establishes a self-amplifying pyroptosis-STING-IFN-β circuit for CD8⁺ T cell immunoactivation. [PDF]

Mater Today Bio
Jing P, Wang L, Qiu X, Chen L, Xie D, Yu Y, Li B, Yan S, Wang G, Zhong Z, Fu W.   +10 more
europepmc   +1 more source

IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer. [PDF]

J Exp Clin Cancer Res
Ren T, Chen X, Wang X, Xu Y, Shao N.
europepmc   +1 more source

Neutrophil extracellular traps and pyroptosis: a molecular nexus linking systemic autoimmune diseases to atherosclerosis. [PDF]

Front Immunol
Du Y, Zhang L, Cheng Y, Lu S, Ou R, Deng X.   +5 more
europepmc   +1 more source

Nuclear gasdermin E drives endothelin-1-induced metastatic progression independently of the pyroptosis. [PDF]

Cell Death Dis
Roman C, Caprara V, Tocci P, Sacconi A, Blandino G, Bagnato A, Sestito R.   +6 more
europepmc   +1 more source