Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources
Modulation of STAT3 signaling, cell redox defenses and cell cycle checkpoints by β-caryophyllene in cholangiocarcinoma cells: possible mechanisms accounting for doxorubicin chemosensitization and chemoprevention [PDF]
, 2020 Cholangiocarcinoma (CCA) is an aggressive group of biliary tract cancers, characterized by late diagnosis, low effective chemotherapies, multidrug resistance, and poor outcomes.
Di Giacomo, Silvia +8 more
core +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyObjetivo: Comparar os parâmetros das análises do controle de qualidade realizados dos concentrados de hemácias filtrados (CHF), produzidos no Banco de Sangue de São Paulo, no período de 2022 e 2023.
AP Sessin +5 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Verificar os motivos da inaptidão clínica em relação ao sexo doador do Banco de Sangue São Paulo no período de janeiro a dezembro de 2022. Materiais e método: O presente estudo tem caráter descritivo com abordagem quantitativa utilizando os ...
RA Bento +5 more
doaj +1 more source
Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]
, 2000 Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T. +11 more
core +1 more source
Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
Advanced Functional Materials, EarlyView.A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyObjetivo: O objetivo desse trabalho foi analisar a inaptidão sorológica dos doadores de sangue de mobilizações externas realizadas pelo Grupo GSH no período de janeiro a dezembro de 2023. Material e métodos: Trata-se de um estudo retrospectivo de caráter
ACA Pitol +5 more
doaj +1 more source
O IMPACTO DOS PROCEDIMENTOS ESTÉTICOS NO ÍNDICE DE INAPTIDÃO DE DOADORES NO BANCO DE SANGUE
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Demonstrar o impacto dos procedimentos estéticos no índice de inaptidão de doadores no Banco de Sangue Serum Barra do Grupo GSH. Material e métodos: Análise dos dados retirados do sistema informatizado com o quantitativo de inaptos por ...
PD Guimarães +5 more
doaj +1 more source
Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets [PDF]
, 2017 Background: In this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing.
Casteleyn, Christophe +9 more
core +1 more source