Results 41 to 50 of about 46,501 (160)

Roles of GSK3β in odor habituation and spontaneous neural activity of the mouse olfactory bulb. [PDF]

PLoS ONE, 2013
Glycogen synthase kinase 3β (GSK3β), a multifaceted kinase, is abundantly expressed in the brain, including the olfactory bulb (OB). In resting cells, GSK3β is constitutively active, and its over-activation is presumably involved in numerous brain ...
Zhixiang Xu, Li Wang, Guo Chen, Xiaoping Rao, Fuqiang Xu   +4 more
doaj   +1 more source

Glycogen Synthase Kinase 3β (GSK3β) Regulates Myogenic Differentiation in Skeletal Muscle Satellite Cells of Sheep

Animals, 2022
Glycogen synthase kinase 3β (GSK3β) has a vital role in the regulation of many cellular processes. However, the role of GSK3β in muscle cell differentiation in sheep remains unknown. In this study, we investigated the function of GSK3β in skeletal muscle
Jingquan Yang, Haosen Yang, Linjie Wang, Ping Zhou   +3 more
doaj   +1 more source

Additional file 4: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

, 2019
Figure S2. The drugs that were selected from the screen were validated using FACS. The MDA MB 231 reporter cells were treated with all the 11 drugs selected from the screen. Following treatment, the percentage of cells fluorescing red and green were assessed using flow cytometry and plotted for each of the three concentrations to generate the graphs ...
Vijay, Geraldine, Zhao, Na, Hollander, Petra, Toneff, Mike, Joseph, Robiya, Pietila, Mika, Taube, Joseph, Sarkar, Tapasree, Ramirez-Pena, Esmeralda, Werden, Steven, Shariati, Maryam, Gao, Ruli, Sobieski, Mary, Stephan, Clifford, Sphyris, Nathalie, Miura, Noayuki, Davies, Peter, Chang, Jeffrey, Soundararajan, Rama, Rosen, Jeffrey, Mani, Sendurai   +20 more
openaire   +1 more source

GSK3β activity regulates osteoblast differentiation in ADSCs.

, 2013
(A) ADSCs were infected with either the retrovirus expressing GFP, catalytically inactive GSK3β (GSK3β-K85A), constitutively active GSK3β (GSK3β-S9A), or wild-type GSK3β (GSK3β-WT). After 48 hours, cells were harvested for immunoblot analysis for GSK3α/β
Soo Young Lee (104705), Jeong-Eun Huh (104702), Ryeojin Ko (104703), Hyun Ju Jung (104704)   +3 more
core   +1 more source

Additional file 2: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

, 2019
Data S2. Summary of results from the high-throughput screen and the detailed red/green readout for each drug tested in the screen. (PDF 3424â kb)
Vijay, Geraldine, Zhao, Na, Hollander, Petra, Toneff, Mike, Joseph, Robiya, Pietila, Mika, Taube, Joseph, Sarkar, Tapasree, Ramirez-Pena, Esmeralda, Werden, Steven, Shariati, Maryam, Gao, Ruli, Sobieski, Mary, Stephan, Clifford, Sphyris, Nathalie, Miura, Noayuki, Davies, Peter, Chang, Jeffrey, Soundararajan, Rama, Rosen, Jeffrey, Mani, Sendurai   +20 more
openaire   +1 more source

GSK3β is downregulated in polarized CaLu-3 cells 18 h post-GSK3β inhibitor (SB415286) treatment.

, 2012
A) Total mRNA expression of GSK3β in control (white) or SB415286 (black) treated CaLu-3 epithelia (four biological replicates per condition measured in duplicate in each qPCR assay; mean values from three independent experiments relative to control+SE of
Abimbola O. Kolawole (119296), Katherine J. D. A. Excoffon (119303), Adriana E. Kajon (119301), Susan B. Core (119299), Priyanka Sharma (77226)   +4 more
core   +1 more source

Variations in the Wnt/β-Catenin Pathway Key Genes as Predictors of Cervical Cancer Susceptibility [Corrigendum]

Pharmacogenomics and Personalized Medicine, 2020
Wang B, Wang M, Li X, Yang M, Liu L. Pharmgenomics Pers Med. 2020;13:157—165. Page 157, Abstract, Results section, the text “The mutant alleles of rs3864004 (A) and rs2293303 (T) located in CTNNB1 showed 1.513 (1.038–2 ...
Wang B, Wang M, Li X, Yang M, Liu L
doaj  

Deciphering the evolution of composite-type GSKIP in mitochondria and Wnt signaling pathways.

PLoS ONE, 2022
We previously revealed the origin of mammalian simple-type glycogen synthase kinase interaction protein (GSKIP), which served as a scavenger and a competitor in the Wnt signaling pathway during evolution.
Cheng-Yu Tsai, Shean-Jaw Chiou, Huey-Jiun Ko, Yu-Fan Cheng, Sin-Yi Lin, Yun-Ling Lai, Chen-Yen Lin, Chihuei Wang, Jiin-Tsuey Cheng, Hsin-Fu Liu, Aij-Li Kwan, Joon-Khim Loh, Yi-Ren Hong   +12 more
doaj   +1 more source

Additional file 1: of Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway

, 2018
Table S1. Slit3 expression and patient characteristics in cohort 1. Table S2. Slit3 expression and patient characteristics in cohort 2. (PDF 78 kb)
Lui Ng, Chow, Ariel, Man, Johnny, Yau, Thomas, Wan, Timothy, Iyer, Deepak, Kwan, Virginia, Poon, Ronnie, Pang, Roberta, Wai-Lun Law   +9 more
openaire   +1 more source

GSK3β overexpression reverses radioresistance of U87R cells.

, 2014
(A) Transfection of GSK3β vector increased GSK3β protein expression.
Songhua Xiao (322277), Qing Liu (20889), Zhen Yang (107412), Ming Wu (238132), Yiwei Liao (635768), Jia Zhao (511806), Ruiyan Lv (635767)   +6 more
core   +1 more source