Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
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Michaelis-Menten kinetics of RasGAP proteins by a rapid fluorescence-based assay. [PDF]
MethodsPaul ME, Vish KJ, Boggon TJ.
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KRAS-targeted therapies in colorectal cancer: a systematic analysis of mutations, inhibitors, and clinical trials. [PDF]
NPJ Precis OncolNavarro-Jiménez M +4 more
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Expression and GTP Sensitivity of Peptide Histidine Isoleucine High‐Affinity‐Binding Sites in Rat
, 2006 Colin Debaigt +8 more
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Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
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Funding manual : employment-based initial teacher training : for academic year 2011/12 [PDF]
, 2011 core
Energetics of activation of GTP hydrolysis on the ribosome
Nature Communications, 2013 G. Wallin, S. C. Kamerlin, J. Åqvist
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Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
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Ataluren-Induced Functional Restoration of Neurofibromin in Fibroblasts From Neurofibromatosis Type 1 Patients With Nonsense Mutations. [PDF]
MedComm (2020)Kim S +8 more
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