Results 161 to 170 of about 80,664 (305)

Translational reprogramming under heat stress: a plant's perspective. [PDF]

R Soc Open Sci
Smith M, Taqrir Akramin A, Balcerowicz M.   +2 more
europepmc   +1 more source

Flexoelectric Polarization‐Enhanced Gd‐Based Nanoflowers for Efficient Phosphatase‐Mimicking Dephosphorylation

Small Structures, EarlyView.
Flexoelectric polarization is harnessed to dynamically enhance phosphatase‐mimicking catalysis in Gd‐based nanoflowers, enabling ultrasound‐responsive and efficient biophosphate ester hydrolysis through strain‐induced electronic modulation. Phosphatase‐mimicking nanozymes provide highly stable enzyme‐like activity but remain limited by their static ...
Linjing Su, Jingyan Xu, Rong Huang, Jinlan Liao, Lixue Zhao, Ling Li, Zhi Zhang, Yuhao Xiong   +7 more
wiley   +1 more source

Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner. [PDF]

Front Cell Dev Biol
Mathiesen SB, Støle TP, Romaine A, Lunde M, Martinsen M, Aronsen JM, Sjaastad I, Louch WE, Christensen G, Carlson CR.   +9 more
europepmc   +1 more source

Differential gene expression in Chorthippus parallelus (Zetterstedt, 1821) (Orthoptera: Acrididae: Gomphocerinae) induced by Wolbachia infection

Insect Science, EarlyView.
Distinct lineages of the grasshopper Chorthippus parallelus (Orthoptera: Acrididae) form a well‐known hybrid zone (HZ) in the Pyrenees mountain range; the Iberian endemism C. p. erythropus (Cpe) and the subspecies C. p. parallelus, (Cpp) widely distributed throughout the rest of Europe. Both subspecies differ in diverse traits, including the strains of
Patricia Jiménez‐Florido, Mónica Aquilino, David Buckley, José L. Bella, Rosario Planelló   +4 more
wiley   +1 more source

Novel paradigms in KRAS targeting: Unveiling strategies to combat drug resistance. [PDF]

Chin Med J (Engl)
Luo X, Zhou F, Tang Y, Liu X, Xiao R, Gu M, Bai J, Jiang D, Yang G, You L, Zhao Y.   +10 more
europepmc   +1 more source

Telomerase modRNA Offers a Novel RNA‐Based Approach to Treat Human Pulmonary Fibrosis

Aging Cell, EarlyView.
Recombinant linear and circular hTERT mRNA restore telomerase activity in primary ATII cells and ex vivo lung tissue from patients with pulmonary fibrosis, leading to telomere elongation, reduced DNA damage, and decreased senescence and fibrosis markers.
Jia Li Ye, Klaudia Grieger, Dongchao Lu, Christina Brandenberger, Malte Juchem, Maria Jordan, Lea Oehlsen, Patrick Zardo, Christopher Werlein, Christina Hesse, Katherina Sewald, Sandy Tretbar, Thomas Thum, Shambhabi Chatterjee, Christian Bär   +14 more
wiley   +1 more source

Targeting clathrin-mediated endocytosis: recent advances in inhibitor development, mechanistic insights, and therapeutic prospects. [PDF]

RSC Med Chem
Zhang C, Guo J, Liu Z, Huang X, Dong S, Hu C, Xiao J.   +6 more
europepmc   +1 more source

Translational Remodeling of the Synaptic Proteome During Aging

Aging Cell, EarlyView.
Aging induces a decoupling of protein regulation between the soma and the synapse. In particular, transcripts coding for ribosomal proteins decrease and their corresponding proteins increase in the synapse while the opposite happens in the soma. At the same time, synapse‐specific regulation of splicing takes place.
Cinzia Caterino, Martino Ugolini, William Durso, Kristina Jevdokimenko, Marco Groth, Konstantin Riege, Matthias Görlach, Eugenio Fornasiero, Alessandro Ori, Steve Hoffmann, Alessandro Cellerino   +10 more
wiley   +1 more source

The GTPase κB-Ras is an essential subunit of the RalGAP tumor suppressor complex. [PDF]

J Biol Chem
Rasche R, Apken LH, Titze S, Michalke E, Singh RK, Oeckinghaus A, Kümmel D.   +6 more
europepmc   +1 more source

Regulation of the MAPK/ERK Pathway by miRNA‐27b in Gastric Cancer: Diagnostic Implications and Therapeutic Potential of Aloin

Asia-Pacific Journal of Clinical Oncology, EarlyView.
ABSTRACT Background Globally, gastric cancer (GC) ranks as the fourth most deadly and fifth most prevalent kind of cancer. Appropriate treatment methods, precise etiology, and molecular processes of GC are still unclear. Methods In silico and quantitative real‐time reverse transcription polymerase chain reaction (qRT‐PCR)‐based expression of miRNA‐27b ...
Yang Dehuo, Wang Ying, Cao Lin
wiley   +1 more source