Results 251 to 260 of about 104,548 (291)

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout, Marie‐Christine Maurel   +1 more
wiley   +1 more source

Dynamic Coupling of MAPK Signaling to the Guanine Nucleotide Exchange Factor GEF-H1. [PDF]

Onco Targets Ther
Leguay K, Kent OA.
europepmc   +1 more source

Coupling of Intracellular Calcium Homeostasis and Formation and Secretion of Matrix Vesicles: Their Role in the Mechanism of Biomineralization. [PDF]

Cells
Margiotta A.
europepmc   +1 more source

TRIM proteins: A 'swiss army knife' of antiviral immunity. [PDF]

PLoS Pathog
Chabot E, Durantel D, Lucifora J.
europepmc   +1 more source

Cytohesin-4/ARF6 facilitates the progression of acute myeloid leukemia through activating PIK3R5/PI3K/AKT pathway. [PDF]

iScience
Qiu XF, He CM, Zeng YM, Deng XL, Liang GL, Zhong MX, Zou M, Xiong XJ, Zhang JD, Ye Y, Niu Q, Chen XL.   +11 more
europepmc   +1 more source

Role of FHOD1 in tumor cells and tumor immune microenvironment. [PDF]

Front Immunol
Yang Y, Kang Z, Cai J, Jia S, Fan S, Zhu H.   +5 more
europepmc   +1 more source

A noncanonical GTPase signaling mechanism controls exit from mitosis in budding yeast. [PDF]

Proc Natl Acad Sci U S A
Zhou X, Weng SY, Bell SP, Amon A.
europepmc   +1 more source

Regulation of small GTP-binding proteins by insulin [PDF]

Biochemical Society Transactions, 2006
Several members of the extensive family of small GTP-binding proteins are regulated by insulin, and have been implicated in insulin action on glucose uptake. These proteins are themselves negatively regulated by a series of specific GAPs (GTPase-activating proteins).
Ingeborg Hers, Matthew Wherlock, Jeremy M. Tavaré, Gavin I. Welsh   +3 more
openaire   +2 more sources