Results 261 to 270 of about 104,548 (291)

Developmentally regulated GTP-binding protein-2 regulates adipocyte differentiation

Biochemical and Biophysical Research Communications, 2021
Developmentally regulated GTP-binding protein 2 (DRG2) participates in the regulation of proliferation and differentiation of multiple cells. However, whether DRG2 regulates adipocyte differentiation and related metabolic control remains elusive. This study revealed increases in body weight and adiposity in DRG2 transgenic (Tg) mice overexpressing DRG2.
Nal Ae Yoon, Byong Seo Park, Byong Seo Park, Byung Ju Lee, Hye Li Im, Jae Geun Kim, Thai Hien Tu, Jeong Woo Park   +7 more
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Small GTP-binding proteins and their regulators in cardiac hypertrophy

Journal of Molecular and Cellular Cardiology, 2008
Small GTP-binding proteins (small G proteins) act as GDP-GTP-regulated molecular switches and are activated by guanine nucleotide exchange factors (GEFs) in response to diverse extracellular stimuli. During this last decade, numerous molecular and cellular studies, as well as genetically-modified animal models, have highlighted the role of small G ...
Isabelle Hmitou, Isabelle Hmitou, Eric Morel, Eric Morel, Frank Lezoualc'h, Frank Lezoualc'h, Nicolas Duquesnes, Nicolas Duquesnes, Mélanie Métrich, Mélanie Métrich   +9 more
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Regulation of Rod GTP Binding Protein by Guanine Nucleotides1

The Journal of Biochemistry, 1984
The rod GTP-binding protein in the bovine disk membrane seems to exist as oligomers in the dark. G alpha and G beta do not interact strongly, and G gamma may be required for G alpha . GDP to dimerize.
Hitoshi Shichi, Robert L. Somers
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Tumour suppressors and the regulation of GTP-binding protein activity

Trends in Cell Biology, 1993
GTP-binding proteins regulate a wide variety of intracellular signalling pathways in eukaryotic cells. The Ras GTP-binding proteins have received a great deal of attention since they were found to be modified by amino acid substitutions in a large number of cancers.
Isabelle Rey, Alan Hall
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DRG: A novel developmentally regulated GTP-binding protein

Biochemical and Biophysical Research Communications, 1992
Using a subtraction cloning approach we had previously isolated a series of murine cDNA clones representing the genes predominantly expressed in the embryonic brain and down-regulated during development. We now report that one of these cDNA clones encodes a novel type of GTP-binding protein.
Makoto Noda, Yoji Ikawa, Yasuhiro Tomooka, Sharad Kumar, Takashi Sazuka   +4 more
openaire   +3 more sources

The GTP-binding protein, Go9 regulates neuronal calcium channels

Nature, 1987
In neuronal cells, opioid peptides and opiates inhibit neurotransmitter release, which is a calcium-dependent process. They also inhibit adenylyl cyclase, presumably via the membrane signal-transducing component, Gi, a guanine nucleotide-binding protein (G-protein). No causal relationship between these two events has yet been demonstrated.
Günter Schultz, J. Hescheler, Walter Rosenthal, W. Trautwein   +3 more
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Regulation of vesicular transport by GTP-binding proteins

Current Opinion in Nephrology and Hypertension, 1995
Intracellular protein trafficking occurs in a series of transport vesicles. Vesicle trafficking is regulated both by heterotrimeric and monomeric GTP-binding proteins (G proteins). Recent studies have explored effector systems used by heterotrimeric G proteins and by monomeric ADP-ribosylation factor G proteins for regulation of vesicle budding.
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Regulation of Protein Trafficking by GTP-Binding Proteins

2009
In eukaryotic cells, specific mechanisms allow selective packaging of proteins and lipids into transport vesicles, which can then specifically recognize the membrane of the acceptor compartment and fuse with it to deliver their cargo. Formation, transport and docking of vesicles are based on a complex network of interactions between regulatory ...
Florence Niedergang, Philippe Chavrier, Michel Franco   +2 more
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Distribution and Regulation of RAB3C, a Small Molecular Weight GTP-Binding Protein

Biochemical and Biophysical Research Communications, 1994
We have investigated the expression and regulation of rab3C in rat tissues and rat pheochromocytoma PC12 cells by using a polyclonal antibody that specifically recognizes this protein. Rab3C was expressed in the neuroendocrine systems, as is its highly homologous family member, rab3A.
Lung-Sen Kao, Yijuang Chern, Ming-Hsien Tsai, Yu Liang, Ying-Yueh Chu, Yi-Chi Su   +5 more
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Regulation of phagocyte function by low molecular weight GTP‐binding proteins [PDF]

European Journal of Haematology, 1993
Abstract:  The mechanisms used by phagocytic leukocytes in the process of bacterial killing are regulated by GTP‐binding proteins of the Ras superfamily. In particular, the formation of toxic oxygen metabolites via the NADPH oxidase requires the action of both Rac and Rap1A proteins.
openaire   +2 more sources