Results 201 to 210 of about 142,607 (261)

Pan-RAS Inhibitors: Expanding Therapeutic Potential and Evading Resistance. [PDF]

Cancers (Basel)
Ramesh S, Wang J, Huang CH, Moore AM, Fadlalla K, Berry KL, Maxuitenko YY, Chen X, Keeton AB, El-Rayes B, Buchsbaum DJ, Budhwani KI, Zhou G, Mitra AK, Piazza GA.   +14 more
europepmc   +1 more source

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions. [PDF]

Proc Natl Acad Sci U S A
Silva JM, Canche L, Cheng A, Young LC, McCormick F.   +4 more
europepmc   +1 more source

Nucleotide-dependent switching and RIPb effector recognition of the barley susceptibility factor RACB. [PDF]

Commun Biol
Mohamadi M, Bradai M, Janowski R, Günsel U, Tran M, Kahl SM, McCollum C, Niessing D, Hückelhoven R, Hagn F.   +9 more
europepmc   +1 more source

Structures and mechanism of E2-CBASS anti-phage system. [PDF]

mLife
Xiao J, Yan Y, Li J, Oyejobi GK, Lan D, Zhu B, Wang Z, Wang L.   +7 more
europepmc   +1 more source

IQGAP3, the overlooked oncogenic twin of IQGAP1: mapping its interactome and functional roles across cellular signaling and cancer. [PDF]

Cell Commun Signal
Basu S, Dixit M.
europepmc   +1 more source

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GTP-binding proteins in plants

Cellular and Molecular Life Sciences CMLS, 1999
GTP-binding proteins are found in all organisms. They are important switches that cycle between an active and an inactive state, ensuring vectorial flow of information on the expense of guanosine triphosphate (GTP). In this review, we discuss current progress in the molecular characterization and functional analysis of plant genes encoding ...
F, Bischoff, A, Molendijk, C S, Rajendrakumar, K, Palme   +3 more
openaire   +2 more sources

Small GTP-Binding Proteins

Physiological Reviews, 2001
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and Ran families.
Y, Takai, T, Sasaki, T, Matozaki
openaire   +2 more sources

GTP-binding proteins in plants

Plant Molecular Biology, 1993
Abstract Full length cDNAs of small GTP-binding proteins were inserted into PGEM1 under the control of the T7 promotor as described previously (Chavrier et al. 1990; Huber et al. 1993). GTP-binding proteins were then transiently expressed in BHK 21 cells with the T7 RNA polymeraserecombinant vaccinia virus system (Fuerst et al.
Terryn, N., van Montagu, Marc, Inzé, Dirk   +2 more
openaire   +3 more sources

The Rheb family of GTP-binding proteins

Cellular Signalling, 2004
Rheb proteins represent a novel and unique family of the Ras superfamily GTP-binding proteins that is conserved from yeast to human. Biochemical studies establish that they bind and hydrolyze GTP. Molecular modeling studies reveal a few structural differences between Rheb and Ras, which may suggest that residues involved in biochemical activities ...
Paul-Joseph, Aspuria, Fuyuhiko, Tamanoi
openaire   +2 more sources