Results 31 to 40 of about 5,611 (205)

Sinorhizobium meliloti Flavin Secretion and Bacteria-Host Interaction: Role of the Bifunctional RibBA Protein

Molecular Plant-Microbe Interactions, 2014
Sinorhizobium meliloti, the nitrogen-fixing bacterial symbiont of Medicago spp. and other legumes, secretes a considerable amount of riboflavin. This precursor of the cofactors flavin mononucleotide and flavin adenine dinucleotide is a bioactive molecule
Svetlana N. Yurgel, Jennifer Rice, Elizabeth Domreis, Joseph Lynch, Na Sa, Zeeshan Qamar, Sathish Rajamani, Mengsheng Gao, Sanja Roje, Wolfgang D. Bauer   +9 more
doaj   +1 more source

Preparation of Isotope-labeled Dihydroneopterin 3'-Triphosphate with High Specific Activity

Pteridines, 1990
Isotope-labeled dihydroneopterin 3'-triphosphate with 3H at positions C-1' and C-2', respectively, has been prepared from isotope-labeled glucose as starting material. Glucose was first converted enzymatically to ribose 5-phosphate.
Katzenmeier Gerd, Schwarzkopf Bruno, Van Quang Le, Schmid Cornelia, Bacher Adelbert   +4 more
doaj   +1 more source

Biosynthetic Enzymes of Tetrahydrolimipterin from Green Sulfur Bacterium Chlorobium Limicola

Pteridines, 1998
Based on the structure of limipterin (Cha, Pfleiderer, and Yim, Helv, Chim. Acta, 78: 600-614. 1995 the biosynthetic pathway for the newly identified pterin glycoside was investigated. It was demonstrated that tetrahydrolimipterin (H4 -limipterin) can be
Kang Dongmin, Kim Sangjoon, Yim Jeongbin
doaj   +1 more source

Mutant human torsinA, responsible for early-onset dystonia, dominantly suppresses GTPCH expression, dopamine levels and locomotion in Drosophila melanogaster

Biology Open, 2015
Dystonia represents the third most common movement disorder in humans with over 20 genetic loci identified. TOR1A (DYT1), the gene responsible for the most common primary hereditary dystonia, encodes torsinA, an AAA ATPase family protein.
Noriko Wakabayashi-Ito, Rami R. Ajjuri, Benjamin W. Henderson, Olugbenga M. Doherty, Xandra O. Breakefield, Janis M. O'Donnell, Naoto Ito   +6 more
doaj   +1 more source

Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina

Frontiers in Microbiology, 2020
Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its exact role in lipogenesis is unclear.
Hongchao Wang, Hongchao Wang, Chen Zhang, Chen Zhang, Haiqin Chen, Haiqin Chen, Zhennan Gu, Zhennan Gu, Jianxin Zhao, Jianxin Zhao, Hao Zhang, Hao Zhang, Hao Zhang, Yong Q. Chen, Yong Q. Chen, Yong Q. Chen, Wei Chen, Wei Chen, Wei Chen   +18 more
doaj   +1 more source

Primers and probes for GTP-cyclohydrolase I mRNA reverse transcriptase polymerase chain reaction. [PDF]

, 2015
Primers and probes for GTP-cyclohydrolase I mRNA reverse transcriptase polymerase chain reaction.
J. Brice Weinberg (271620), Alicia D. Volkheimer (701241), Tsin W. Yeo (218400), Bert K. Lopansri (271621), Donald L. Granger (271619), Esther D. Mwaikambo (323802), Keith Hyland (142148), Nicholas M. Anstey (35535), Matthew P. Rubach (323793), Jackson Mukemba (323796), Salvatore Florence (323797)   +10 more
core   +1 more source

Neopterin and Cytokines in Hereditary Dystonia and Parkinson's Disease

Pteridines, 1999
Both neopterin and biopterin concentrations in cerebrospinal fluid from patients with Parkinson's disease, in which the nigrostriatal dopamine neurons degenerate, were lower than those from age-matched older control subjects.
Nagatsu T., Ichinose H., Mogi M., Togari A.   +3 more
doaj   +1 more source

Expanded motor and psychiatric phenotype in autosomal dominant Segawa syndrome due to GTP cyclohydrolase deficiency. [PDF]

, 2006
Contains fulltext : 49888.pdf (Publisher’s version ) (Closed access)BACKGROUND: Segawa syndrome due to GTP cyclohydrolase deficiency is an autosomal dominant disorder with variable expression, that is clinically characterised by l-dopa ...
Steyaert, J., Hedrich, K., Romstad, A., Hove, J.L. van, Matthijs, G., Blau, N., Legius, E., Casaer, P., Klein, C., Theys, P., Moller, L.B., Goriounov, D., Wevers, R.A.   +12 more
core   +1 more source

GTP cyclohydrolase I and tyrosine hydroxylase gene mutations in familial and sporadic dopa-responsive dystonia patients. [PDF]

PLoS ONE, 2013
Dopa-responsive dystonia (DRD) is a rare inherited dystonia that responds very well to levodopa treatment. Genetic mutations of GTP cyclohydrolase I (GCH1) or tyrosine hydroxylase (TH) are disease-causing mutations in DRD.
Chunyou Cai, Wentao Shi, Zheng Zeng, Meiyun Zhang, Chao Ling, Lei Chen, Chunquan Cai, Benshu Zhang, Wei-Dong Li   +8 more
doaj   +1 more source

Tetrahydrobiopterin Synthesis in Rat Cardiac Myocytes; An Event Required for Cytokine-induced NO Generation

Pteridines, 1998
Cardiac myocytes are known to express the high-capacity inducible isoform of nitric oxide (NO) synthase (iNOS). Since tetrahydrobiopterin (BH4) is an essential cofactor for NO formation, we investigated whether BH4 synthesis is required for cytokine ...
Hattori Yoshiyuki, Nakanishi Nobuo, Gross Steven S., Kasai Kikuo   +3 more
doaj   +1 more source