Results 11 to 20 of about 1,011,564 (289)

GTPase-Activating Proteins for Cdc42 [PDF]

Eukaryotic Cell, 2002
The Rho-type GTPase, Cdc42, has been implicated in a variety of functions in the yeast life cycle, including septin organization for cytokinesis, pheromone response, and haploid invasive growth. A group of proteins called GTPase-activating proteins (GAPs)
Gregory R. Smith, S. Givan, P. Cullen, G. Sprague   +3 more
semanticscholar   +4 more sources

Characterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases. [PDF]

J Biol Chem, 2014
Background: ELMOD proteins are atypical GAPs for the ARF family with links to deafness. Results: ELMOD proteins have distinct specific activities for ARF proteins and bind the non-opioid sigma-1 receptor.
Ivanova AA, East MP, Yi SL, Kahn RA.
europepmc   +2 more sources

β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of Apc^Min/+ Mice [PDF]

Molecules
A Rho-GTPases are pivotal regulators of key cellular processes implicated in colorectal cancer (CRC) progression, yet the roles of their regulatory proteins, particularly GTPase-activating proteins (GAPs), remain poorly understood.
Eladio A. Velasco-Sampedro, Cristina Sánchez-Vicente, María J. Caloca   +2 more
doaj   +2 more sources

Arabidopsis RopGAPs Are a Novel Family of Rho GTPase-Activating Proteins that Require the Cdc42/Rac-Interactive Binding Motif for Rop-Specific GTPase Stimulation

Plant Physiology, 2000
The plant-specific Rop subfamily of Rho GTPases, most closely related to the mammalian Cdc42 and Rac GTPases, plays an important role in the regulation of calcium-dependent pollen tube growth, H(2)O(2)-mediated cell death, and many other processes in ...
Guang Wu, Hai Li, Zhenbiao Yang
openalex   +3 more sources

Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. [PDF]

Mol Biol Cell, 2013
Small GTPases control many functions in cells, and the TBC GTPase-activating protein family modulates the activity of the largest G protein subfamily, Rabs.
Gabernet-Castello C, O'Reilly AJ, Dacks JB, Field MC.   +3 more
europepmc   +2 more sources

Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.

J Cell Sci, 2016
Zhou W, Li X, Premont RT.
europepmc   +2 more sources

Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization. [PDF]

Sci Signal, 2012
Wang Y, He H, Srivastava N, Vikarunnessa S, Chen YB, Jiang J, Cowan CW, Zhang X.   +7 more
europepmc   +2 more sources

Rho-GTPases subfamily: cellular defectors orchestrating viral infection [PDF]

Cellular & Molecular Biology Letters
Ras homolog gene family-guanosine triphosphatases (Rho-GTPases), key molecular switches regulating cytoskeletal dynamics and cellular signaling, play a pivotal role in viral infections by modulating critical processes such as viral entry, replication ...
Beibei Zhang, Shuli Li, Juntao Ding, Jingxia Guo, Zhenghai Ma, Hong Duan   +5 more
doaj   +2 more sources

Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis. [PDF]

Sci Signal, 2013
King PD, Lubeck BA, Lapinski PE.
europepmc   +2 more sources

Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies [PDF]

Biology Open
Kasumi Suzuki, Yoshitaka Okawa, Sharmin Akter, Haruki Ito, Yoko Shiba   +4 more
doaj   +2 more sources