Results 221 to 230 of about 274,715 (359)

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

A Novel Depletion Technique for Studying the Role of Protein L12 in the Activation of Ribosome-Dependent GTPases

, 2013
Michelle E. Wuerth
openalex   +1 more source

CRMP5-associated GTPase (CRAG) Is a Candidate Driver Gene for Colorectal Cancer Carcinogenesis [PDF]

, 2018
Dai Shimizu, Takaaki Masuda, Kuniaki Sato, Yusuke Tsuruda, Hajime Otsu, Yosuke Kuroda, Hidetoshi Eguchi, Yasuhiro Kodera, Koshi Mimori   +8 more
openalex   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Single-molecule fluorescence and cross-linking reveal ligand-gated Toc34 oligomerization dynamics. [PDF]

Biophys J
Penneru SK, Tiruvadi-Krishnan S, Lamichhane R, Bruce BD.   +3 more
europepmc   +1 more source

A. baumannii A1S_0934 is a COG0523 protein with conserved metal-binding and GTPase motifs.

Jeanette M. Critchlow (21553796), Joseph S. Rocchio (21553799), Melanie C. McKell (10801005), Courtney J. Campbell (21553802), Juan P. Barraza (21553805), Evan S. Krystofiak (21553808), Erin R. Green (21553811), Tae Akizuki (21553814), Walter J. Chazin (112842), Michael S. VanNieuwenhze (550001), Timothy L. Stemmler (1333977), David P. Giedroc (1560214), Eric P. Skaar (112846)   +12 more
openalex   +1 more source

Overexpression of RhoA, Rac1, and Cdc42 GTPases Is Associated with Progression in Testicular Cancer [PDF]

, 2004
Takao Kamai, Tomonori Yamanishi, Hiromichi Shirataki, Kentaro Takagi, Hidekazu Asami, Yuji Ito, Ken‐Ichiro Yoshida   +6 more
openalex   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Pan-cancer analyses identify oncogenic drivers, expression signatures, and therapeutic vulnerabilities in RHO GTPase pathway genes. [PDF]

Front Bioinform
Fernández R, Lorenzo-Martín LF, Quesada V, Bustelo XR.   +3 more
europepmc   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source