Results 141 to 150 of about 133,980 (384)

Synthesis of an arginine mimic for an antifungal octapeptide library : this thesis is presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2008
A family of bioactive antifungal octapeptides has been established¹⁻³. The template for this library is based on peptides composed of two predefined amino acids, three arginines, and three unknown components. The arginine contains a guanidino group (pKa =
Sun, Hao
core  

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

Macromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz, Cevin P. Braksch, Jonas De Breuck, Matthias Hartlieb, Meike N. Leiske   +4 more
wiley   +1 more source

Synthalin, Buformin, Phenformin, and Metformin: A Century of Intestinal “Glucose Excretion” as Oral Antidiabetic Strategy in Overweight/Obese Patients

Livers
After the first release of synthalin B (dodecamethylenbiguanide) in 1928 and its later retraction in the 1940s in Germany, the retraction of phenformin (N-Phenethylbiguanide) and of Buformin in the USA (but not outside) because of the lethal complication
Giuliano Pasquale Ramadori
doaj   +1 more source

Bioinspired, Guanidinium, and Indole Modified Poly(glycidyl ether)s as Highly Efficient Vectors for Polyplex‐Mediated Gene Delivery

Macromolecular Rapid Communications, EarlyView.
Guanidinium‐ and indole‐functionalized poly(glycidyl ether)s were developed as non‐viral gene delivery vectors with tunable hydrophilic–hydrophobic balance. All polymers formed stable DNA polyplexes, while moderate indole content yielded the highest transfection efficiency at low N/P ratios.
Markus Kötzsche, Andreas Dzierza, Lennert Sölter, Jan Egger, Kjell Cornelis, Andreas Stihl, Felix H. Schacher, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Effect of Exfoliated, Oxidized Molybdenum Disulfide on Mechanical and Tribological Properties of NBR/BR Blends

Polymer Composites, EarlyView.
Decreased wear‐induced weight loss of an NBR/BR blend by adding exfoliated, oxidized MoS2 nanosheets. ABSTRACT Enhancing wear resistance is crucial for improving the durability of rubber products while minimizing the release of rubber particles into the environment.
Seyed Rasoul Mousavi, Samaneh Salkhi Khasraghi, Majed Amini, Mohammad Arjmand   +3 more
wiley   +1 more source

Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers. [PDF]

, 2020
Tumor-associated p53 mutations endow cells with malignant phenotypes, including chemoresistance. Amyloid-like oligomers of mutant p53 transform this tumor suppressor into an oncogene.
de Oliveira, Guilherme AP, Ferretti, Giulia DS, Gratton, Enrico, Lima, Flavia RS, Motta, Michelle F, Norberto, Douglas R, Pedrote, Murilo M, Silva, Jerson L, Spohr, Tania CLS   +8 more
core   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

Pest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus, Liina Soonvald, Iris Callewaert, Ana Isabel Silva, Ericmar Ávila Dos Santos, Silva Vilumets, Riina Kaasik, Sven Vereecken, Lenny Van Daele, Peter Dubruel, Jonathan Willow, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +13 more
wiley   +1 more source

Basicity of N‐(Tetramesityltetraphosphacyclopentylidene)cyclohexylamine: An Unusual Diphospha(III)guanidine Derivative [PDF]

, 2017
Anup K. Adhikari, Toni Grell, Peter Lönnecke, Evamarie Hey‐Hawkins   +3 more
openalex   +1 more source

Interfacial Dipole Engineering With Taurine‐Modified SnO2 Electron Transport Layer for Efficient and Stable Perovskite Solar Cells

Rare Metals, EarlyView.
ABSTRACT Organic‐inorganic metal halide perovskite solar cells (PSCs) are promising for photovoltaics due to their excellent optoelectronic properties. However, achieving high efficiency and stability remains challenging, mainly due to defects and energy losses at the electron transport layer (ETL)/perovskite interface.
Jiahui Jin, Yutao Li, Xiaoye Liu, Xinxuan Yang, Fengyou Wang, Lin Fan, Xiaoyan Liu, Jinghai Yang, Lili Yang   +8 more
wiley   +1 more source

Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors [PDF]

, 2017
Yuliya V. Korolkova, Tatyana N. Makarieva, Kseniya M. Tabakmakher, Larisa K. Shubina, Ekaterina Kudryashova, Yaroslav A. Andreev, И. В. Мошарова, Hyi‐Seung Lee, Yeon‐Ju Lee, Sergey A. Kozlov   +9 more
openalex   +1 more source