Results 141 to 150 of about 46,713 (191)

Assessment of Risk Factors Related to Environmental Factors and Herd Management for Bovine Respiratory Syncytial Virus and Bovine Parainfluenza Virus‐3 Infections Frequently Observed in Beef and Dairy Cattle

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
In this study, molecular diagnosis of BRSV and BPIV3 factors was aimed and risk factors were tried to be determined by considering ‘environmental factors’, ‘herd management factors’ and ‘infection‐related factors.’ RT‐PCR technique was used for the molecular detection of pathogens and multivariate and univariate statistical analyses were performed ...
Ali Küçük, Yakup Yildirim, Bekir Çetintav   +2 more
wiley   +1 more source

Water‐Triggered Direct Air Capture by Strong Organic Bases

ChemSusChem, Volume 18, Issue 11, June 2, 2025.
Peralkylated guanidines capture CO₂ directly from moist air and release concentrated CO₂ upon water co‐evaporation with a smalltemperature‐swing of 45 °C. This water‐triggered capture and release mechanism enables a high working capacity of nearly one equivalent CO2 per base, offering a promising approach for direct air capture.
Anders Grundtvig Utzon, Ji‐Woong Lee
wiley   +1 more source

Access to Highly Functional and Polymerizable Carbonate‐Drug Conjugates

ChemSusChem, Volume 18, Issue 11, June 2, 2025.
A generic protocol for drug‐functionalized and carbon dioxide‐based six‐membered cyclic carbonates has been developed. These functional carbonates can be designed for effective ring‐opening polymerization to forge polycarbonates that support a controllable amount of a given drug and additional functionality, opening up complementary strategies for ...
Wangyu Shi, Thirusangumurugan Senthamarai, Matteo Lanzi, Paolo Orlando, Rodrigo Nogués Martín, Arjan W. Kleij   +5 more
wiley   +1 more source

Application of Carbon Quantum Dots in Food Business: A Comprehensive Review

eFood, Volume 6, Issue 3, June 2025.
This approach is straightforward and practical in comparison to previous approaches because it speeds up the synthesis of CQDs while maintaining a high quantum yield. By heating the poly (ethylene glycol) (PEG‐200) for 2–10 min. However, there are several downsides of this technique, such as the nonuniform particle sizes of carbon quantum dots that ...
Muhammad Sadiq Naseer, Ali Imran, Qaswaa Yousif Jameel, Ashok Kumar Bishoyi, Faiyaz Ahmed, Ahmed Elawady, Pranchal Rajput, Fakhar Islam, Tahir Zahoor, Abdela Befa Kinki, Saima Naz   +10 more
wiley   +1 more source

The microbiologist's guide to metaproteomics

iMeta, Volume 4, Issue 3, June 2025.
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative   +31 more
wiley   +1 more source

A single buried cysteine acts as a hydrophobic stabilizer of a folding intermediate and transition state in the MATH domain of SPOP

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Cysteine is a highly conserved amino acid with diverse roles in protein function. Whilst its role in the formation of disulfide bridges is well characterized, the contribution of isolated cysteines in protein folding is by and large unexplored. Here we investigate the impact of cysteine residues on the folding pathway of the MATH domain in the
Livia Pagano, Awa Diop, Valeria Pennacchietti, Mariana Di Felice, Eduarda S. Ventura, Julian Toso, Angelo Toto, Stefano Gianni   +7 more
wiley   +1 more source

CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin‐proteasome pathway

Protein Science, Volume 34, Issue 6, June 2025.
Abstract CXXC5, as a member of the zinc‐finger CXXC family proteins, interacts with unmodified CpG dinucleotides to modulate the expression of genes involved in cellular proliferation, differentiation, and death in physiology and pathophysiology. Various signaling pathways, including mitogenic 17β‐estradiol (E2), contribute to the expression and ...
Hazal Ayten, Pelin Toker, Gizem Turan Duman, Çağla Ece Olgun, Öykü Deniz Demiralay, Büşra Bınarcı, Gizem Güpür, Pelin Yaşar, Hesna Begüm Akman, Per Haberkant, Mesut Muyan   +10 more
wiley   +1 more source

Using a stable protein scaffold to display peptides that bind to alpha‐synuclein fibrils

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Amyloid fibrils are ordered aggregates that are a pathological hallmark of many neurodegenerative disorders including Alzheimer's disease and Parkinson's disease. The process of amyloid formation involves a complex cascade by which soluble monomeric protein converts to insoluble, ordered aggregates (amyloid fibrils).
Samuel Bismut, Matthias M. Schneider, Masashi Miyasaki, Yuqing Feng, Ellis J. Wilde, M. Dylan Gunawardena, Tuomas P. J. Knowles, Gabrielle S. Kaminski Schierle, Laura S. Itzhaki, Janet R. Kumita   +9 more
wiley   +1 more source

In Vitro Structure–Activity Relationship Stability Study of Antisense Oligonucleotide Therapeutics Using Biological Matrices and Nucleases

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT The primary degradation pathway for antisense oligonucleotides (ASOs) involves endonuclease and exonuclease‐mediated breakdown. The effect of various chemical modifications on the stability of oligonucleotides has not been systematically investigated.
Jelena Lovrić, Jingjing Yan, XueQing Li, Tony Karlsborn, Mattias Bood, Anders Dahlén, Constanze Hilgendorf, Deepak Kumar Bhatt   +7 more
wiley   +1 more source

N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production

Journal of Peptide Science, Volume 31, Issue 6, June 2025.
The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley   +1 more source