Results 151 to 160 of about 46,713 (191)

Polyamine Metabolism Promotes the Progression of Thyroid Carcinoma by Regulating the Immune Phenotype of Tumor Associated Macrophages

Smart Medicine, Volume 4, Issue 2, June 2025.
This study reveals that polyamine metabolism significantly impacts thyroid carcinoma progression by modulating tumor‐associated macrophage phenotypes, influencing tumor growth and immune responses. ABSTRACT Polyamine metabolism is a key regulator of cellular proliferation and immune modulation, and its dysregulation is implicated in multiple carcinoma ...
Haoran Ding, Lingling Xue, Shaoshi Zhu, Ziyu Wang, Huan Gui, Guang Zhang, Ning Tang, Haozhen Ren, Dayu Chen   +8 more
wiley   +1 more source

HalALMT1 mediates malate efflux in the cortex of mature cluster rootlets of Hakea laurina, occurring naturally in severely phosphorus‐impoverished soil

New Phytologist, Volume 246, Issue 6, Page 2597-2616, June 2025.
Summary Hakea laurina, a woody Proteaceae, naturally occurs in severely phosphorus (P)‐impoverished habitats in southwest Australia. It develops distinctive cluster roots that exhibit a high capacity for carboxylate exudation and acid phosphatase activity, contributing to its P acquisition.
Hirotsuna Yamada, Lydia Ratna Bunthara, Akira Tanaka, Takuro Kohama, Hayato Maruyama, Wakana Tanaka, Sho Nishida, Tantriani, Akira Oikawa, Keitaro Tawaraya, Toshihiro Watanabe, Shu Tong Liu, Patrick M. Finnegan, Hans Lambers, Takayuki Sasaki, Jun Wasaki   +15 more
wiley   +1 more source

A Shift in Begomovirus coheni Populations Associated With Tomato Yellow Leaf Curl Disease Infecting Tomato Cultivars in the Southeastern United States

Plant Pathology, Volume 74, Issue 5, Page 1277-1289, June 2025.
A shift in Begomovirus coheni populations associated with tomato yellow leaf curl disease (TYLCD) in tomato cultivars might facilitate the emergence of tomato yellow leaf curl virus‐Georgia (TYLCV‐GA) in natural conditions. ABSTRACT Tomato yellow leaf curl virus (TYLCV) is a major pathogen causing tomato yellow leaf curl disease (TYLCD), significantly ...
Manish Kumar, Sudeep Bag, Theodore McAvoy, Ty Torrance, Cale Cloud, Alvin M. Simmons   +5 more
wiley   +1 more source

Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine

CA: A Cancer Journal for Clinicians, Volume 75, Issue 3, Page 226-242, May/June 2025.
Abstract Cancer molecular imaging is the noninvasive visualization of a process unique to or altered in neoplasia, such as proliferation, glucose metabolism, and receptor expression, which is relevant to patient management. Several molecular imaging modalities are now available, including magnetic resonance, optical, and nuclear imaging.
Malik E. Juweid, Soud F. Al‐Qasem, Fadlo R. Khuri, Andrea Gallamini, Philipp Lohmann, Hans‐Joachim Ziellenbach, Felix M. Mottaghy   +6 more
wiley   +1 more source

Meprin β Modulates Brevican Proteolysis Impairing Neural Plasticity and Memory Formation

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
Meprin β was studied using mice overexpressing it in cortical and hippocampal neurons. N‐terminomics identified brevican, a key extracellular matrix protein associated with synaptic plasticity and memory, as a potential substrate of meprin β. Further analyses revealed that brevican levels are dependent on the catalytic activity of meprin β.
Maximilian Keller, Celine Gallagher, Simon Kreiselmaier, Kira Bickenbach, Ulrich Schmitt, Liana Marengo, Dayan Taghikhah, Mohammad Abukhalaf, Andreas Tholey, Christoph Becker‐Pauly, Thomas Mittmann, Claus U. Pietrzik   +11 more
wiley   +1 more source

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

Angewandte Chemie, Volume 137, Issue 22, May 26, 2025.
Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok, Dmytro Bratiichuk, Hilda Sucipto, Nils Gummerlich, Marc Stierhof, Oleksandr Gromyko, Franziska Fries, Victor Fedorenko, Rolf Müller, Josef Zapp, Maksym Myronovskyi, Andriy Luzhetskyy   +11 more
wiley   +2 more sources

Macrocycles of Saxitoxin: Insights into the Structure of Zetekitoxin AB

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Synthetic macrocycles of (+)‐saxitoxin, the causative agent of paralytic shellfish poisoning, have been prepared. These are designed to mimic the macrocyclic core of the proposed structure for zetekitoxin AB. Interestingly, these synthetic macrocycles do not form the C12 hydrate as commonly observed in this family of toxins, casting doubt on the ...
Wenyuan Li, Srinivas R. Paladugu, Jordan P. Liles, Manju Karthikeyan, Kevin Chase, Shrinivasan Raghuraman, Matthew S. Sigman, Ryan E. Looper   +7 more
wiley   +1 more source

Imino‐Pyrrole Zn(II) Complexes for the Rapid and Selective Chemical Recycling of Commodity Polymers

Angewandte Chemie, Volume 137, Issue 22, May 26, 2025.
Three imino‐pyrrole zinc (II) catalysts were prepared and applied to the chemical recycling of PLA, PET, and BPA‐PC. Rapid PLA degradation was accomplished in solution and under solvent‐free conditions, the latter giving full conversion at relatively mild temperatures after 11 min.
Jack A. Stewart, Louis T. W. Powell, Matthew J. Cullen, Gabrielle Kociok‐Köhn, Matthew G. Davidson, Matthew D. Jones   +5 more
wiley   +2 more sources

Click Conjugates of Artificial Ribonucleases: Sequence Specific Cleavage with Multiple Turnover

Chemistry – A European Journal, Volume 31, Issue 30, May 27, 2025.
A trisbenzimidazole catalyst was attached to central positions of DNA and DNA‐LNA oligonucleotides. The resulting conjugates bind complementary RNA strands and cleave them with multiple turnover and substrate half‐lives down to 3.5 hours. Up to 98.8% of cleavage occurs in a single site.
Sandra Weber, Timo Weinrich, Ute Scheffer, Elisabeth Kalden, Michael W. Göbel   +4 more
wiley   +1 more source

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The coordination chemistry of guanidines and guanidinates

Coordination Chemistry Reviews, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Stuart Pace, Philip J. Bailey
openaire   +3 more sources