Safety and efficacy of a feed additive consisting of guanidinoacetic acid and its preparation (GuanAMINO®) for chickens for fattening, chickens reared for laying, chickens reared for reproduction, turkeys for fattening, turkeys reared for reproduction (Evonik Operations GmbH) [PDF]
EFSA JournalFollowing a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of guanidinoacetic acid (GAA) and its preparation (GuanAMINO®) as zootechnical additives for chickens for fattening, chickens ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
doaj +3 more sources
Efficacy of Supplementary Guanidinoacetic Acid at Different Dietary Crude Protein Levels on the Productive Performance, Egg Quality, Intestinal Morphology, Antioxidative Status, and Serum Metabolites of Aged Laying Hens Exposed to High Ambient Temperatures [PDF]
Veterinary Medicine and ScienceBackground Prior research has established that high ambient temperature and diets with reduced protein content exert detrimental effects on egg production and quality and the overall health of poultry.
Reza Mahdavi +4 more
doaj +3 more sources
PLoS ONE, 2022 Guanidinoacetic acid (GAA) is the only precursor for the creatine synthesis of vertebrates. Creatine (Cr) and phosphocreatine (PCr) are able to provide energy for the rapid growth and development of the muscle tissue.
Shiqi Zhang +7 more
doaj +4 more sources
Cataloguing guanidinoacetic acid content in nutritional supplements. [PDF]
Food Sci Nutr, 2023 AbstractGuanidinoacetic acid (GAA, also known as glycocyamine or guanidinoacetate) is a naturally occurring alpha amino acid derivative and newly recognized dietary compound obtainable by different foods and nutritional supplements. Anecdotal evidence suggests that the GAA exposure from supplements might be a major source of GAA supply, out‐competing ...
Ostojic SM +3 more
europepmc +4 more sources
Dietary Guanidinoacetic Acid Supplementation Improves Growth Performance of Plateau Yaks Through Plasma Metabolome Modulation [PDF]
BiologyThis study aimed to investigate the effects of dietary guanidinoacetic acid (GAA) supplementation on yak physiology by evaluating growth performance, serum biochemical indices and plasm metabolomic profiles to elucidate the underlying regulatory ...
Yinjie You +9 more
doaj +2 more sources
Dietary guanidinoacetic acid supplementation improves rumen metabolism, duodenal nutrient flux, and growth performance in lambs [PDF]
Frontiers in Veterinary ScienceGuanidinoacetic acid (GAA) is the only precursor of creatine, which is an important energy source for growth and metabolism. The degradation of guanidinoacetic acid in rumen plays a decisive role in its application in ruminant diet.
Shiqi Zhang +6 more
doaj +2 more sources
Guanidinoacetic acid in human nutrition: Beyond creatine synthesis. [PDF]
Food Sci Nutr, 2023 AbstractGuanidinoacetic acid (GAA) is a nutrient that has been used in human nutrition since the early 1950s. Recommended for its role in creatine biosynthesis, GAA demonstrated beneficial energy‐boosting effects in various clinical conditions. Dietary GAA has also been suggested to trigger several creatine‐independent mechanisms.
Ostojic SM, Jorga J.
europepmc +4 more sources
Hepatic metabolism of guanidinoacetic acid on broilers [PDF]
Revista Brasileira de ZootecniaThe objective of this study was to evaluate the hepatic metabolism and performance of broilers fed reduced-energy diets (50 kcal/kg less), with or without guanidinoacetic acid (GAA).
Paulo Henrique Sousa da Paz +8 more
doaj +2 more sources
Effect of Guanidinoacetic Acid Supplementation on the Performance of Calves Fed Milk Replacer [PDF]
AnimalsGuanidinoacetic acid (GAA) is the direct precursor to creatine, which serves as an energy reserve mechanism in the body. We evaluated the effects of GAA supplementation on the growth performance of calves fed milk replacer.
Kathryn J. Hazlewood +8 more
doaj +2 more sources
Guanidinoacetic Acid Attenuates Adipogenesis through Regulation of miR-133a in Sheep [PDF]
Animals, 2023 Guanidinoacetic acid (GAA) is an amino acid derivative, previously described in the skeletal muscle of vertebrates, that serves as an important regulator of cellular bioenergetics and has been widely used as a feed additive.
Jia-Min Zhao +6 more
doaj +2 more sources