EFFECTS OF GUANIDINOACETIC ACID SUPPLEMENTATION IN BROILER CHICKEN DIET ON CARCASS CHARACTERISTICS
Guanidinoacetic acid (GAA) is a natural organic acid in the body that acts as a precursor of creatine which plays the role of energy carrier in the cell This study was conducted to determine the effects of supplementing broiler chicken feed with GAA on ...
Ngazi Chaari Gabriel , Lucy Kabuage , Purity Nguhiu and Charles Gachuiri
core +1 more source
Birds fed with vegetable diets rely on the endogenous synthesis of creatine, which requires amino acids, some of which, for example arginine (Arg), are considered essential for several physiological and metabolic functions.
Elisangela Vanroo +6 more
core +1 more source
Effects of Guanidinoacetic Acid Supplementation to Broiler Diets With Varying Energy Content [PDF]
An experiment was conducted to determine the response of broiler chickens to guanidinoacetic acid (GAA) added to diets with different energy levels during fattening to 35 days of age.
Carlos de la Cruz +5 more
core +1 more source
Age-Related Changes in Serum Guanidinoacetic Acid in Women
Guanidinoacetic acid (GAA) is a fundamental intermediate in cellular bioenergetics, with circulating levels of GAA often reflects disturbances in its conversion due to many intrinsic and extrinsic factors, including gender or age. Here, we evaluated serum GAA in 172 healthy women aged 18 to 65 years, with age found to significantly predict serum GAA ...
A, Olah +4 more
openaire +2 more sources
Oxidative stress‐induced changes in wooden breast and mitigation strategies: A review
Abstract Wooden breast (WB) is a multifactorial muscular abnormality resulting from the interplay between genetic predispositions for rapid growth, physiological stress, and anatomical impairments. This myopathy has been a persistent challenge in the poultry industry since its initial identification a decade ago.
Yaqin Wang +6 more
wiley +1 more source
A creatine efflux transporter in oligodendrocytes
Creatine deficiency leads to severe neurodevelopmental disorders. In the brain, creatine is synthesized by oligodendrocytes to supply neighboring neurons. While SLC6A8 mediates neuronal uptake, the creatine release mechanism was unclear. Our results establish SLC22A15 as a key creatine efflux transporter.
Svenja Flögel +3 more
wiley +1 more source
Effects of patent foramen ovale in migraine: a metabolomics‐based study
Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong +15 more
wiley +1 more source
Effects of guanidinoacetic acid supplementation on liver and breast muscle fat deposition, lipid levels, and lipid metabolism-related gene expression in ducks [PDF]
Exogenous supplementation of guanidinoacetic acid can mechanistically regulate the energy distribution in muscle cells. This study aimed to investigate the effects of guanidinoacetic acid supplementation on liver and breast muscle fat deposition, lipid ...
Jiajun Xie +6 more
core +1 more source
Urinary Excretion of Guanidinoacetic Acid in Rats with Diabetic Nephropathy
Urinary guanidinoacetic acid (GAA) is a sensitive marker for gentamicin nephrotoxicity in rats. This study assesses the usefulness of GAA concentrations in the diagnosis of renal tubular injury in diabetic nephropathy. Serum, urine, and renal cortex samples were obtained from rats 1, 2, and 3 weeks after streptozotocin injection (65 mg/kg body weight).
I, Kiyatake, T, Nakamura, H, Koide
openaire +2 more sources
Novel Insights Into Gyrate Atrophy of the Choroid and Retina (GACR): A Cohort Study
ABSTRACT Gyrate atrophy of the choroid and retina (GACR, OMIM #258870) is a rare inherited metabolic disorder characterized by progressive chorioretinal degeneration and hyperornithinemia. Current therapeutic modalities potentially slow disease progression but are not successful in preventing blindness.
Berith M. Balfoort +35 more
wiley +1 more source

