Safety and efficacy of a feed additive consisting of guanidinoacetic acid and its preparation (GuanAMINO®) for chickens for fattening, chickens reared for laying, chickens reared for reproduction, turkeys for fattening, turkeys reared for reproduction (Evonik Operations GmbH) [PDF]
EFSA Journal, Volume 23, Issue 12, December 2025.Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of guanidinoacetic acid (GAA) and its preparation (GuanAMINO®) as zootechnical additives for chickens for fattening, chickens reared for laying, chickens reared for reproduction, turkeys for fattening, turkeys reared for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
wiley +3 more sources
Guanidinoacetic Acid Significantly Improves Growth, Antioxidant Capacity, and Nonspecific Immunity for Juvenile Litopenaeus vannamei [PDF]
Aquaculture Nutrition, Volume 2025, Issue 1, 2025.Guanidinoacetic acid (GAA)—a nutritional additive—is essential for the healthy growth of aquatic animals. The experiment was conducted to examine the effects of dietary GAA on growth, muscle amino acid composition, antioxidative indices, and nonspecific immunity for juvenile Litopenaeus vannamei. Total 800 healthy shrimp (initial mean weight = 0.27 ± 0.
Huaxing Lin +4 more
wiley +3 more sources
Efficacy of Supplementary Guanidinoacetic Acid at Different Dietary Crude Protein Levels on the Productive Performance, Egg Quality, Intestinal Morphology, Antioxidative Status, and Serum Metabolites of Aged Laying Hens Exposed to High Ambient Temperatures [PDF]
Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.0.15% GAA supplementation enhanced body weight and productive performance in heat‐stressed aged hens. Serum creatine, nitric oxide, and antioxidant capacity increased with GAA, while egg quality remained unaffected. One percent reduced protein diet with GAA maintained performance, whereas 2% reduction caused losses.
Reza Mahdavi +4 more
wiley +2 more sources
Supplementation with Guanidinoacetic Acid in Women with Chronic Fatigue Syndrome [PDF]
Nutrients, 2016 A variety of dietary interventions has been used in the management of chronic fatigue syndrome (CFS), yet no therapeutic modality has demonstrated conclusive positive results in terms of effectiveness. The main aim of this study was to evaluate the effects of orally administered guanidinoacetic acid (GAA) on multidimensional fatigue inventory (MFI ...
Sergej Ostojic +5 more
openaire +4 more sources
Dietary guanidinoacetic acid supplementation improves rumen metabolism, duodenal nutrient flux, and growth performance in lambs [PDF]
Front Vet SciGuanidinoacetic acid (GAA) is the only precursor of creatine, which is an important energy source for growth and metabolism. The degradation of guanidinoacetic acid in rumen plays a decisive role in its application in ruminant diet.
Kailun Yang +6 more
core +2 more sources
Guanidinoacetic Acid as a Precursor of Creatine for Cattle
Kansas Agricultural Experiment Station Research Reports, 2015 Creatine serves as an energy-storing molecule in muscle, and in mammals it can be synthesized in the liver from guanidinoacetic acid (GAA). With this study, we evaluated whether GAA supplementation would lead to creatine production in cattle similarly to other species.
M. Ardalan +3 more
openaire +4 more sources
Effect of Guanidinoacetic Acid and Zilpaterol Hydrochloride Feed Additions on Lambs’ Productive Performance, Carcass Characteristics, and Blood Chemistry [PDF]
Animals (Basel)Simple Summary: The present study evaluates the effects of two dietary supplements (guanidinoacetic acid [GAA] and zilpaterol hydrochloride [ZLH]) on the productive performance of fattening lambs over a 60-day period.
Peña-Avelino, L. Y. +4 more
core +3 more sources
Effect of arginine, glycine + serine concentrations, and guanidinoacetic acid supplementation in vegetable-based diets for chickens [PDF]
Poult Sci: The study investigated guanidinoacetic acid (GAA) supplementation with varying dietary digestible arginine (Arg) and glycine+serine (Gly+Ser) concentrations in the starter phase, exploring respective carry-over effects on growth performance, blood ...
Lucas Wachholz +12 more
core +2 more sources
Safety and efficacy of a feed additive consisting of guanidinoacetic acid (Creamino®) for turkeys for fattening and reared for breeding (Alzchem Trostberg GmbH) [PDF]
EFSA Journal, Volume 23, Issue 4, April 2025.Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of guanidinoacetic acid (GAA) when used as zootechnical additive in feed and water for drinking for turkeys for fattening and turkeys reared for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +21 more
wiley +2 more sources
Efficacy of a feed additive consisting of guanidinoacetic acid (Creamino®) for weaned piglets and pigs for fattening in water for drinking (Alzchem Trostberg GmbH) [PDF]
EFSA Journal, Volume 23, Issue 4, April 2025.Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the efficacy of guanidinoacetic acid (GAA; Creamino®), intended for use as zootechnical additive (functional group: other zootechnicals – improvement of performance ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
wiley +2 more sources