Results 121 to 130 of about 320,673 (337)
Self-assembled guanine ribbons as wide-bandgap semiconductors
, 2001 We present a first principle study about the stability and the electronic properties of a new biomolecular solid-state material, obtained by the self-assembling of guanine (G) molecules.
A. Calzolari +20 more
core +1 more source
Structural and Thermodynamic Origins of Ligand Specificity in Homologous PDZ Domains from the Tiam-Family of Guanine Exchange Factors [PDF]
, 2011 Ernesto J. Fuentes, Tyson R. Shepherd
openalex +1 more source
Advanced Science, EarlyView.A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin +6 more
wiley +1 more source
Change in Nutritional Status Modulates the Abundance of Critical Pre-initiation Intermediate Complexes During Translation Initiation \u3cem\u3ein Vivo\u3c/em\u3e [PDF]
, 2007 In eukaryotic translation initiation, eIF2∙GTP–Met-tRNAiMet ternary complex (TC) interacts with eIF3–eIF1–eIF5 complex to form the multifactor complex (MFC), while eIF2∙GDP associates with eIF2B for guanine nucleotide exchange.
Anderson, James T. +8 more
core +1 more source
Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis [PDF]
, 2013 Mélanie Laurin +8 more
openalex +1 more source
Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases
Advanced Science, EarlyView.Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim +8 more
wiley +1 more source
Clinics, 2019 OBJECTIVE: In this study, the relationship between osteoporotic vertebral fractures and 9041 Guanine/Adenine and 3673 Guanine/Adenine polymorphisms related to the vitamin K epoxide reductase complex subunit-1 (VKORC1) gene in postmenopausal women with ...
Merih Ozgen +9 more
doaj +1 more source
Thermodynamic and kinetic insights into stop codon recognition by release factor 1. [PDF]
, 2014 Stop codon recognition is a crucial event during translation termination and is performed by class I release factors (RF1 and RF2 in bacterial cells). Recent crystal structures showed that stop codon recognition is achieved mainly through a network of ...
Joseph, Simpson +2 more
core
Nanozymes Integrated Biochips Toward Smart Detection System
Advanced Science, EarlyView.This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source