Results 151 to 160 of about 158,534 (314)
Lack of correlation between the presence of 7-methyl guanine in deoxyribonucleic acid and ribonucleic acid of organs and the localization of tumours after a single carcinogenic dose of N-methyl-N-nitrosourethane [PDF]
R. Schoental
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Tunable G‐Quadruplex Ligands: Azobenzene Derivatives for Light‐Controlled DNA Modulation
Azobenzene (AB) is a promising light‐responsive motif for targeting G‐quadruplexes (G4 s) and enabling their light‐controlled modulation. We synthesized a series of novel AB derivatives with diverse structural variations, demonstrating that the interaction mode influences its ability to modulate G4 properties bidirectionally.
Aleksandra Matusiak+4 more
wiley +1 more source
Abstract Objectives The congenital diaphragmatic hernia (CDH), characterized by malformation of the diaphragm and lung hypoplasia, is a common and severe birth defect that affects around 1 in 4000 live births. However, the etiology of most cases of CDH remains unclear.
Marie Boisson+11 more
wiley +1 more source
Carbon Metabolism of Glycine and Serine in Relation to the Synthesis of Organic Acids and a Guanine Derivative [PDF]
Dalton Wang, R. H. Burris
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Using N1‐methyladenosine, a cancer biomarker as a target, a highly selective DNA aptamer was obtained with excellent selectivity and affinity, allowing the detection with a limit of detection of 1.9 µm. Abstract N1‐methyladenosine (m1A) level in urine increases in the presence of cancer and is associated with the tumor size and stage.
Esra Bağda, Efkan Bağda, Juewen Liu
wiley +1 more source
Abstract Despite differences in behaviors and living conditions, vertebrate organisms share the great majority of proteins, often with subtle differences in amino acid sequence. Here, we present a simple way to analyze the difference in amino acid occurrence by comparing highly homologous proteins on a subproteome level between several vertebrate model
Zhen‐Lu Li, Matthias Buck
wiley +1 more source
Effects of Cooling on the Fluorescence of Biological Guanine Derivatives. [PDF]
Hans Chr. Børresen+3 more
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Altering the connecting positions of two 2‐amino‐1,8‐naphthyridine units modulates binding to distinct DNA and RNA motifs. This structural variation influences molecular interactions, affecting stacking tendencies and hydrogen bonding. The positional differences determine how these molecules recognize cytosine‐rich sequences, impacting their ability to
Bimolendu Das+5 more
wiley +1 more source