Results 151 to 160 of about 158,534 (314)

Tunable G‐Quadruplex Ligands: Azobenzene Derivatives for Light‐Controlled DNA Modulation

open access: yesChemistry – A European Journal, EarlyView.
Azobenzene (AB) is a promising light‐responsive motif for targeting G‐quadruplexes (G4 s) and enabling their light‐controlled modulation. We synthesized a series of novel AB derivatives with diverse structural variations, demonstrating that the interaction mode influences its ability to modulate G4 properties bidirectionally.
Aleksandra Matusiak   +4 more
wiley   +1 more source

Copy number variations analysis in a cohort of 47 fetuses and newborns with congenital diaphragmatic hernia

open access: yesPrenatal Diagnosis, Volume 42, Issue 13, Page 1627-1635, December 2022., 2022
Abstract Objectives The congenital diaphragmatic hernia (CDH), characterized by malformation of the diaphragm and lung hypoplasia, is a common and severe birth defect that affects around 1 in 4000 live births. However, the etiology of most cases of CDH remains unclear.
Marie Boisson   +11 more
wiley   +1 more source

A Fluorescent Aptasensor for Sensitive and Selective Determination of Epigenetic Cancer Biomarker N1‐Methyladenosine in Urine Samples

open access: yesChemistry – A European Journal, EarlyView.
Using N1‐methyladenosine, a cancer biomarker as a target, a highly selective DNA aptamer was obtained with excellent selectivity and affinity, allowing the detection with a limit of detection of 1.9 µm. Abstract N1‐methyladenosine (m1A) level in urine increases in the presence of cancer and is associated with the tumor size and stage.
Esra Bağda, Efkan Bağda, Juewen Liu
wiley   +1 more source

A proteome‐scale analysis of vertebrate protein amino acid occurrence: Thermoadaptation shows a correlation with protein solvation but less so with dynamics

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 91, Issue 1, Page 3-15, January 2023., 2023
Abstract Despite differences in behaviors and living conditions, vertebrate organisms share the great majority of proteins, often with subtle differences in amino acid sequence. Here, we present a simple way to analyze the difference in amino acid occurrence by comparing highly homologous proteins on a subproteome level between several vertebrate model
Zhen‐Lu Li, Matthias Buck
wiley   +1 more source

THE ESTIMATION OF GUANINE AND XANTHINE

open access: hybrid, 1941
George H. Hitchings
openalex   +1 more source

Effects of Cooling on the Fluorescence of Biological Guanine Derivatives. [PDF]

open access: bronze, 1965
Hans Chr. Børresen   +3 more
openalex   +1 more source

Structure‐Binding Relationship of 2‐Amino‐1,8‐Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition

open access: yesChemistry – A European Journal, EarlyView.
Altering the connecting positions of two 2‐amino‐1,8‐naphthyridine units modulates binding to distinct DNA and RNA motifs. This structural variation influences molecular interactions, affecting stacking tendencies and hydrogen bonding. The positional differences determine how these molecules recognize cytosine‐rich sequences, impacting their ability to
Bimolendu Das   +5 more
wiley   +1 more source

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