Results 151 to 160 of about 316,659 (284)
Identification of a tight junction–associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability [PDF]
, 2003 Gaëlle Benais-Pont +8 more
openalex +1 more source
Flow Cytometry: Advances, Challenges and Trends
BioEssays, EarlyView.Recent advances in flow cytometry span hardware, data processing, and AI‐driven analytics. Emerging modalitiesincluding spectral, imaging, mass, and nano/EV cytometryenable higher‐parameter and small‐particle detection. Integrated machine learning drives a shift from manual gating toward automated multi‐omics workflows.
J. Paul Robinson +2 more
wiley +1 more source
The Rho Guanine Nucleotide Exchange Factor AKAP13 (BRX) Is Essential for Cardiac Development in Mice [PDF]
, 2010 C. Mayers +15 more
openalex +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
BioEssays, EarlyView.Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
BMEMat, EarlyView.PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang +9 more
wiley +1 more source
Effect of pressure on slit channels in hydrate of sodium salt of guanine: a link to nucleobase intermolecular interactions [PDF]
, 2019 A.A. Gaydamaka +4 more
openalex +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
BMEMat, EarlyView.This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
Enhancing CHO cell recombinant protein production using a perfusion‐directed host evolution approach
Biotechnology Progress, EarlyView.Abstract Clonally derived cell lines generated from Chinese hamster ovary (CHO) cells encounter numerous stressors when cultured in high‐intensity perfusion bioreactors leading to poor process performance. To circumvent this, the ability of CHO cells to adapt to different culture environments was exploited. Here host cells were selected in the presence
Peter Amaya +7 more
wiley +1 more source