Results 51 to 60 of about 158,534 (314)
The Journal of Organic Chemistry, 2023 Guanine is one out of five endogenous nucleobases and of key interest in drug discovery and chemical biology. Hitherto, the synthesis of guanine derivatives involves lengthy multistep sequential synthesis of low overall diversity, resulting in the quest for innovation. Using a "single-atom skeletal editing" approach, we designed 2-aminoimidazo[2,1-f][1,
Xin Li +4 more
openaire +3 more sources
Application of Ammonium Persulfate for Selective Oxidation of Guanines for Nucleic Acid Sequencing
Molecules, 2017 Nucleic acids can be sequenced by a chemical procedure that partially damages the nucleotide positions at their base repetition. Many methods have been reported for the selective recognition of guanine.
Yafen Wang +7 more
doaj +1 more source
Self-assembled guanine ribbons as wide-bandgap semiconductors [PDF]
Physica E vol.13/2-4, 1236 (2002), 2001 We present a first principle study about the stability and the electronic properties of a new biomolecular solid-state material, obtained by the self-assembling of guanine (G) molecules. We consider hydrogen-bonded planar ribbons in isolated and stacked configurations.
arxiv +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Guanine crystal formation by bacteria
BMC Biology, 2023 Background Guanine crystals are organic biogenic crystals found in many organisms. Due to their exceptionally high refractive index, they contribute to structural color and are responsible for the reflective effect in the skin and visual organs in ...
María Elisa Pavan +5 more
doaj +1 more source
An Unusual 500,000 Bases Long Oscillation of Guanine and Cytosine Content in Human Chromosome 21 [PDF]
Computational Biology and Chemistry, 28(5-6): 393-399 (2004), 2004 An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21. This oscillation is localized in the rightmost one-eighth region of the chromosome, from 43.5 Mb to 46.5 Mb. Five cycles of oscillation are observed in this region with six GC-rich peaks and five GC-poor valleys ...
arxiv +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
FEBS Open Bio, EarlyView.With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet +6 more
wiley +1 more source
Reviews in Analytical Chemistry, 2011 In this article, the investigation of electrochemical determination of guanine(GU) by 1-phenyl-3-methyl-4-(2-furoyl)-5-pyrazolone (HPMαFP) modified glassy carbon electrode (HPMαFP/GCE) in Aciclovir Dispersible Tablets solution was reported.
Li Xueli, Li Jinzhou
doaj +1 more source
Room temperature self-assembly of cation-free guanine quartet network nucleated from Mo-induced defect on decorated Au(111) with graphene nanoribbons [PDF]
arXiv, 2021 Guanine-quadruplex, consisting of several stacked guanine-quartets (GQs), has emerged as an important category of novel molecular targets with applications from nanoelectronic devices to anticancer drugs. Incorporation of metal cations into GQ structure is utilized to form stable G-quadruplexes, while no other passage has been reported yet.
arxiv