Results 51 to 60 of about 316,659 (284)

Synergistic Regulation of Pigment Cell Precursors’ Differentiation and Migration by ednrb1a and ednrb2 in Nile Tilapia

Cells
The evolutionary loss of ednrb2 in specific vertebrate lineages, such as mammals and cypriniform fish, raises fundamental questions about its functional necessity and potential redundancy or synergy with paralogous endothelin receptors in pigment cell ...
Zilong Wen, Jinzhi Wu, Jiawen Yao, Fugui Fang, Siyu Ju, Chenxu Wang, Xingyong Liu, Deshou Wang   +7 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Radiological Evaluation of Huntington’s Disease: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Huntington’s Disease (HD) is a rare neurodegenerative condition inherited in an autosomal dominant pattern, where Gamma Amino Butyric Acid-ergic (GABAergic) neurons in the basal ganglia progressively deteriorate.
Soumyabrata Debnath, R Harshith
doaj   +1 more source

Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase [PDF]

, 2009
hSMUG1 (human single-stranded selective monofunctional uracil-DNA glyscosylase) is one of three glycosylases encoded within a small region of human chromosome 12. Those three glycosylases, UNG (uracil-DNA glycosylase), TDG (thymine-DNA glyscosylase), and
Agus Darwanto, Akbari, Alcantara, Barrett, Bennett, Bethod, Boorstein, Bryantsev, Cerny, Clough, Cui, Cybulski, Daniel K. Rogstad, Di Noia, Di Noia, Dunning, Fujimoto, Gait, Guerniou, Hansch, Haushalter, Hobza, Jacob A. Theruvathu, James L. Sowers, Jang, Kavli, Kelly, Kendall, Krokan, Krokan, La Francois, Lawrence C. Sowers, Liu, Marten, Masaoka, Matsubara, Matsubara, Matsudaira, Mendes, Morgan, Neddermann, Nilsen, Nilsen, Pearl, Perezjorda, Privat, Rao, Rogstad, SantaLucia, Sibghat-Ullah, Slupphaug, Sousa, Sowers, Sowers, Sugiyama, Tannor, Tod Pascal, Waters, Wibley, William Goddard, Zhao, Zhao, Zhao, Zielenkiewicz   +63 more
core   +3 more sources

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Long range correlations in DNA : scaling properties and charge transfer efficiency [PDF]

, 2003
We address the relation between long range correlations and charge transfer efficiency in aperiodic artificial or genomic DNA sequences. Coherent charge transfer through the HOMO states of the guanine nucleotide is studied using the transmission approach,
Dominique Bicout, Efim Kats, Enrique Maciá, H. E. Hurst, M. Di Ventra, P. Carpena, Stephan Roche, W. Feller, W. Li   +8 more
core   +4 more sources

Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B., Longnecker, Krista   +1 more
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

Synthesis and Spectral Study of New Guanine Derivative (N-((6-Oxo-6,9-Dihydro-1H-Purin-2-yl)Carbamothioyl)Propionamide) and its Complexes with Some Metals Ion

Ibn Al-Haitham Journal for Pure and Applied Sciences
This study included the preparation and characterization of the new guanine derivative (N-((6-oxo-6,9-dihydro-1H-purin-2-yl)carbamothioyl)propionamide), with an exciting chemical structure.
Abdullah Sh. Abdullah Alani, Basima Muhsen Sarhan, Vishwa Deepak Tripathi   +2 more
doaj   +1 more source