Results 61 to 70 of about 159,037 (219)

Rheoscopic Fluids in a Post-Kalliroscope World [PDF]

open access: yesD. Borrero-Echeverry, C.J. Crowley and T.P. Riddick, Phys. Fluids 30, 087103 (2018), 2018
In rheoscopic flow visualization, the working fluid is seeded with small reflective flakes that align preferentially in the flow due to their anisotropy. This leads to directed light scattering, which can be exploited to distinguish qualitatively different regions of the flow.
arxiv   +1 more source

Real-Time Monitoring of Human Guanine Deaminase Activity by an Emissive Guanine Analog

open access: yesACS Chemical Biology, 2021
Guanine deaminase (GDA) deaminates guanine to xanthine. Despite its significance, the study of human GDA remains limited compared to other metabolic deaminases. As a result, its substrate and inhibitor repertoire are limited, and effective real-time activity, inhibitory, and discovery assays are missing.
Bucardo M. S.   +5 more
openaire   +5 more sources

An Electrochemical DNA Biosensor for Carcinogenicity of Anticancer Compounds Based on Competition between Methylene Blue and Oligonucleotides

open access: yesSensors, 2019
A toxicity electrochemical DNA biosensor has been constructed for the detection of carcinogens using 24 base guanine DNA rich single stranded DNA, and methylene blue (MB) as the electroactive indicator.
Nor Diyana Md. Sani   +7 more
doaj   +1 more source

Long range correlations in DNA : scaling properties and charge transfer efficiency [PDF]

open access: yesPhys. Rev. Lett. 91, 228101 (2003), 2003
We address the relation between long range correlations and charge transfer efficiency in aperiodic artificial or genomic DNA sequences. Coherent charge transfer through the HOMO states of the guanine nucleotide is studied using the transmission approach, and focus is made on how the sequence-dependent backscattering profile can be inferred from ...
arxiv   +1 more source

Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1

open access: yesMolecules, 2015
The human 8-oxoguanine DNA glycosylase OGG1 is involved in base excision repair (BER), one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer. We envisage that potent inhibitors of
Tushar R. Mahajan   +4 more
doaj   +1 more source

The intermolecular dimer potential for guanine

open access: yesThe Journal of Chemical Physics, 2017
The ab initio intermolecular potential of guanine has been developed with the help of a combination of symmetry-adapted perturbation theory and density functional theory (DFT). The resulting potential has been globally optimized to locate the guanine cluster structures up to tetramers.
Artür Manukyan, Adem Tekin
openaire   +4 more sources

Spin transport and polarization properties of manganese-doped dual-guanine molecule [PDF]

open access: yesarXiv, 2014
We study the spin transport and polarization properties of manganese-doped dual-guanine molecules connected to graphene leads using non-equilibrium Green's function method. It is shown that a manganese doped dual-guanine molecule is a biological semiconductor and behaves as a prefect spin filter.
arxiv  

Global deformation facilitates flipping of damaged 8-oxo-guanine and guanine in DNA [PDF]

open access: yesNucleic Acids Research, 2016
Oxidation of guanine (Gua) to form 7,8-dihydro-8-oxoguanine (8oxoG) is a frequent mutagenic DNA lesion. DNA repair glycosylases such as the bacterial MutM can effciently recognize and eliminate the 8oxoG damage by base excision. The base excision requires a 8oxoG looping out (flipping) from an intrahelical base paired to an extrahelical state where the
Martin Zacharias, Giuseppe La Rosa
openaire   +4 more sources

THEORETICAL STUDY OF THE NON-WATSON-CRICK BASE PAIR GUANINE-GUANINE [PDF]

open access: yesJournal of the Chilean Chemical Society, 2010
ABSTRACT A theoretical study of the non canonical base pair, Guanine-Guanine (G-G) has been carried out in the frame of molecular orbital theory using density functional theory (DFT). The Becke three parameter hybrid including correlation functional that contains local and non-local terms (B3LYP) was used thoroughly.
MADARIAGA, S. TERESA   +1 more
openaire   +2 more sources

Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

open access: yesActa Dermato-Venereologica, 2020
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
doaj   +1 more source

Home - About - Disclaimer - Privacy