Results 111 to 120 of about 52,163 (306)

Expression, purification, crystallization and X-ray data collection for RAS and its mutants

Data in Brief, 2016
This article expands on crystal structure data for human H-RAS with mutations at position Y137, briefly described in a paper on the effects of phosphorylation of Y137 by ABL kinases (Tyrosine phosphorylation of RAS by ABL allosterically enhances effector
Christian W. Johnson, Greg Buhrman, Pamela Y. Ting, John Colicelli, Carla Mattos   +4 more
doaj   +1 more source

HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase. [PDF]

Anal Biochem, 2021
Hannan JP, Swisher GH, Martyr JG, Cordaro NJ, Erbse AH, Falke JJ.   +5 more
europepmc   +1 more source

Effect of guanine nucleotides on the conformation and stability of chloroplast elongation factor Tu

, 1989
The effect of guanine nucleotides and kirromycin on the conformation and stability of the chloroplast elongation factor Tu (EF-Tuchl) from Euglena gracilis has been investigated.

core   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Research on the Potential Mechanism of Guanine Nucleotides Enhancing the Tolerance of Lactiplantibacillus plantarum Y12

Foods
This study aims to elucidate the mechanism by which exogenous guanosine monophosphate (GMP) enhances the stress tolerance of Lactiplantibacillus plantarum Y12.
Meichen Sui, Tianhao Zhang, Yaqi Hou, Xueqi Lu, Xiaochen Shi, Zhiyan Wen, Yanfeng Tuo, Guangqing Mu, Fang Qian, Yinglong Song, Xuemei Zhu   +10 more
doaj   +1 more source

Effect of Stress on Blood Levels of Guanine Nucleotides.

Experimental Biology and Medicine, 1966
SummaryStudies using C14-labelled guanylic acid demonstrated a rapid disappearance of these substances from the blood of intact and adrenalectomized rats. The application of tourniquets across the hind limbs of these animals produced a significantly decreased clearance of the label from the blood after the tourniquet was removed.
V W, Hollis, E R, Ramey
openaire   +2 more sources

A Modular Nucleoside Kinase Cascade for the Synthesis of Ribonucleoside Triphosphates

Biotechnology and Bioengineering, EarlyView.
Damm et al. report standardized enzymatic cascades for production of all canonical nucleoside triphosphates from the corresponding nucleosides, using kinase‐catalyzed phosphorylation from acetyl phosphate. Reactions afforded ∼ 100 mM product in near‐quantitative conversion.
Oliver T. Damm, Martin Pfeiffer, Johannes Zöhrer, Bernd Nidetzky   +3 more
wiley   +1 more source

Comparative genomic analysis reveals a critical role of de novo nucleotide biosynthesis for Saccharomyces cerevisiae virulence.

PLoS ONE, 2015
In recent years, the number of human infection cases produced by the food related species Saccharomyces cerevisiae has increased. Whereas many strains of this species are considered safe, other 'opportunistic' strains show a high degree of potential ...
Roberto Pérez-Torrado, Silvia Llopis, Benedetta Perrone, Rocío Gómez-Pastor, Bernhard Hube, Amparo Querol   +5 more
doaj   +1 more source

Aerobic prokaryotes do not have higher GC contents than anaerobic prokaryotes, but obligate aerobic prokaryotes have

BMC Evolutionary Biology, 2019
Background Among the four bases, guanine is the most susceptible to damage from oxidative stress. Replication of DNA containing damaged guanines results in G to T mutations.
Sidra Aslam, Xin-Ran Lan, Bo-Wen Zhang, Zheng-Lin Chen, Li Wang, Deng-Ke Niu   +5 more
doaj   +1 more source

Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase. [PDF]

Protein Sci, 2022
Fernández-Justel D, Marcos-Alcalde Í, Abascal F, Vidaña N, Gómez-Puertas P, Jiménez A, Revuelta JL, Buey RM.   +7 more
europepmc   +1 more source