Results 151 to 160 of about 104,742 (325)

Mutations at position 1122 in the catalytic domain of the mouse ras‐specific guanine nucleotide exchange factor CDC25^Mm originate both loss‐of‐function and gain‐of‐function proteins [PDF]

, 1998
Vittorio Carrera, Andrea Moroni, Enzo Martegani, Celina Volponi, Robbert H. Cool, Lilia Alberghina, Marco Vanoni   +6 more
openalex   +1 more source

Guanine nucleotide exchange factors and colon neoplasia

Frontiers in Cell and Developmental Biology
Despite many diagnostic and therapeutic advances, colorectal cancer (CRC) remains the second leading cause of cancer death for men and women in the United States. Alarmingly, for reasons currently unknown, the demographics of this disease have shifted towards a younger population.
Lea-Pearl Njei, Natalia Sampaio Moura, Alyssa Schledwitz, Kelly Griffiths, Kunrong Cheng, Jean-Pierre Raufman, Jean-Pierre Raufman, Jean-Pierre Raufman, Jean-Pierre Raufman   +8 more
openaire   +3 more sources

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Encoding DNA sequences by integer chaos game representation

, 2017
DNA sequences are fundamental for encoding genetic information. The genetic information may not only be understood by symbolic sequences but also from the hidden signals inside the sequences.
Yin, Changchuan
core  

An intracellular guanine nucleotide release protein for G0. GAP-43 stimulates isolated alpha subunits by a novel mechanism.

, 1991
Stephen M. Strittmatter, Dario Valenzuela, Yuta Sudo, Maurine E. Linder, Mark C. Fishman   +4 more
openalex   +1 more source

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration [PDF]

, 2016
Hadir Marei, Alejandro Carpy, Anna Woroniuk, Claire Vennin, Gavin White, Paul Timpson, Boris Maček, Angeliki Malliri   +7 more
openalex   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

First Report of Homozygous COL7A1 c.5756delG Mutation Causing Recessive Dystrophic Epidermolysis Bullosa in a Non‐Consanguineous Japanese Family

JEADV Clinical Practice, EarlyView.
ABSTRACT Severe recessive dystrophic epidermolysis bullosa (RDEB) is usually caused by biallelic loss‐of‐function mutations in COL7A1. While the c.5756delG variant has been previously reported in heterozygous form, its clinical impact in homozygosity has not been described.
Nozomi Kohama, Sayaka Yamaguchi, Teruki Yanagi, Yumi Akamine, Kimiko Nonaka, Daisuke Utsumi, Kenzo Takahashi   +6 more
wiley   +1 more source

Amphetamine alters Ras-guanine nucleotide-releasing factor expression in the rat striatum in vivo

, 2009
Nikhil K. Parelkar, Qian Jiang, Xiang‐Ping Chu, Ming‐Lei Guo, Li-Min Mao, John Q. Wang   +5 more
openalex   +1 more source

The Graphene Oxide Memristive DNA Sensor for Taxonomic Fingerprint

Macromolecular Materials and Engineering, EarlyView.
A graphene oxide–based memristive DNA sensor enables rapid, label‐free quantification of nucleotide base composition across 37%–55% GC with strong linear calibration. Delivering results within 2–5 min, the platform combines high sensitivity with minimal sample preparation, offering a practical tool for point‐of‐care diagnostics, genetic fingerprinting,
Konstantin G. Nikolaev, Jia Hui Bong, Siyu Chen, Kostya S. Novoselov, Daria V. Andreeva   +4 more
wiley   +1 more source