Results 231 to 240 of about 104,742 (325)

KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis

International Journal of Cancer, Volume 158, Issue 6, Page 1588-1598, 15 March 2026.
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros, Gabriel Oliveira dos Santos, José Claudio Casali‐da‐Rocha, Samuel Aguiar Junior, Virgilio Souza e Silva, Gustavo Nóriz Berardinelli, Augusto Perazzolo Antoniazzi, Rui Manuel Reis, Dirce Maria Carraro, Giovana Tardin Torrezan   +9 more
wiley   +1 more source

Dopamine D1 receptors characterized with [3H]SCH 23390. Solubilization of a guanine nucleotide-sensitive form of the receptor.

, 1986
Hyman B. Niznik, Norman Y. Otsuka, Anne Dumbrille-Ross, Dimitri E. Grigoriadis, Anne Tirpak, Philip Seeman   +5 more
openalex   +1 more source

Integrative machine learning approach for identifying genes associated with quantitative traits: A soybean (Glycine max) yield case study

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract To improve the identification of minor‐effect molecular markers and genes associated with quantitative traits, addressing inefficiencies in traditional molecular marker mining and the limited impact of these markers in practical breeding, we analyzed over 15,000 soybean (Glycine max) genotypes across nine maturity groups using an AI‐driven ...
Wei Zhou, Haoyong Ouyang, Zhengxiao Yan, Jiayi Song, Yichan Li, Zhou Tang, Chang Zhao   +6 more
wiley   +1 more source

Crystal structure of the class V GTP-binding RNA aptamer bound to its ligand: GTP recognition by a topologically complex intermolecular G-quadruplex. [PDF]

Nucleic Acids Res
Stafflinger H, Neißner K, Bartsch S, Pichler AK, Bartosik K, Dhamotharan K, Abele R, Duchardt-Ferner E, Micura R, Schindelin H, Wöhnert J.   +10 more
europepmc   +1 more source

Fine mapping and functional analysis of the candidate gene OFP17, regulating both seed and fruit sizes in cotton

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Single cotton boll weight (BW) and seed index (SI, 100‐seed weight) are key determinants of lint and seed yield, yet their genetic basis remains poorly understood. Here, a stable interploidy introgression line with small boll from Gossypium arboreum in Gossypium hirsutum, NB298, was employed to map quantitative trait loci (QTLs) of BW and SI ...
Min Xu, Liuchun Feng, Susu Liu, Zhechang Zhang, Chenhui Zhou, Guoli Feng, Ningshan Wang, Nijiang Ai, Baoliang Zhou   +8 more
wiley   +1 more source

Crystal structures reveal the distinct features of the 2'-dG-III riboswitch in the purine riboswitch family. [PDF]

Nucleic Acids Res
Chen K, Liao W, Wang J, Ren Y, Lu Z, Peng X, Wang J, Huang L.   +7 more
europepmc   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

Guanine Nucleotide Exchange Factor VAV3 [PDF]

, 2020
openaire   +1 more source

The Marriage of Metal Nanoclusters With Reticular Frameworks: Synthetic Strategies and Biomedical Applications

Aggregate, Volume 7, Issue 2, February 2026.
The integration of metal nanoclusters (MNCs) with reticular frameworks (RFs) has recently emerged as a powerful strategy to create composite materials with enhanced and synergistic functionalities. This review provides an overview of the synthetic strategies developed for constructing MNCs/RFs composites and their recent advances in biomedical ...
Wenfeng Liu, Qinyin Yin, Li‐Li Tan, Li Shang   +3 more
wiley   +1 more source

Auto-luminescence study of thermal unfolding of DNA G-quadruplexes. [PDF]

RSC Adv
Kudrya VY, Dubey IY, Negrutska VV, Naumenko AP.   +3 more
europepmc   +1 more source