Results 231 to 240 of about 99,476 (367)

The inhibitory effect of methanol on forskolin-activated adenylate cyclase in rat erythrocyte membranes dependent on the state of the guanine nucleotide-binding stimulatory and regulatory protein.

, 1988
Osamu Takeda, Kazuo Yamasaki, Hiroshi Kohda, Atsushi Yamashita, Tomonori Kurokáwa, Sadahiko Ishibashi   +5 more
openalex   +2 more sources

Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay. [PDF]

J Biol Chem
Araki M, Kasuya Y, Yoshimoto K, Katada T, Kontani K.   +4 more
europepmc   +1 more source

Klebsiella pneumoniae contributes to altered cytotoxicity of thiopurines in vitro: Possible implications of biotransformation and bacterial metabolism

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin, Cristina Lagatolla, Sofia Sindici Forgiarini, Mathias Haag, Sylvia Karin Neef, Manola Comar, Elke Schaeffeler, Barbara Bellich, Matteo Bramuzzo, Giuliana Decorti, Marianna Lucafò, Ute Hofmann, Matthias Schwab, Gabriele Stocco   +13 more
wiley   +1 more source

Guanine Nucleotide-Binding Regulatory Proteins and Adenylate Cyclase

, 1986
Alfred G. Gilman
openalex   +1 more source

Guanine nucleotides modulate cell surface cAMP-binding sites in membranes from Dictyostelium discoideum [PDF]

, 1984
Peter J.M. Van Haastert
openalex   +1 more source

Guanine quadruplexes mediate mitochondrial RNA polymerase pausing. [PDF]

BMC Biol
Snyder RJ, Shankar U, Delker D, Soerianto W, Burdick JT, Cheung VG, Watts JA.   +6 more
europepmc   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Occurrence of an Inhibitory Guanine Nucleotide‐Binding Regulatory Component of the Adenylate Cyclase System in cyc⁻ Variants of S49 Lymphoma Cells [PDF]

, 1983
Karl H. Jakobs, Ulrich Gehring, Bernhard GAUGLER, Thomas Pfeuffer, Günter Schultz   +4 more
openalex   +1 more source

Elucidating the solution structure of the monomolecular <i>BCL2</i> RNA G-quadruplex: a new robust NMR assignment approach. [PDF]

Chem Sci
Wang Z, Ferreira Rodrigues C, Jurt S, Domínguez-Martín A, Johannsen S, Sigel RKO.   +5 more
europepmc   +1 more source

Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction

Cancer Science, EarlyView.
This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley   +1 more source