Results 281 to 290 of about 99,476 (367)
Neuronal migration plays essential roles in the establishment of mammalian brains, and its impairment causes severe developmental abnormalities and behavioral and cognitive deficits. Here, we report that cadherin‐6 (CDH6), an unusual cadherin molecule containing an RGD integrin‐binding motif in the first extracellular domain, controls the motility of ...
Yuki Hirota+7 more
wiley +1 more source
Coding relationship links RNA G-quadruplexes and protein RGG motifs in RNA-binding protein autoregulation. [PDF]
Adlhart M+3 more
europepmc +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source
Analysis of quadruplex propensity of aptamer sequences. [PDF]
Cucchiarini A+3 more
europepmc +1 more source
ABSTRACT The advancement of epigenetics has highlighted DNA methylation as an intermediate‐omic influencing gene regulation and phenotypic expression. With emerging technologies enabling the large‐scale and affordable capture of methylation data, there is growing interest in integrating this information into genetic evaluation models for animal ...
Adrián López‐Catalina+3 more
wiley +1 more source
Structure of a DNA Glycosylase Bound to a Nicked T:G Mismatch-Containing DNA. [PDF]
Ouzon-Shubeita H+3 more
europepmc +1 more source
Abstract Rhamdia quelen, Rhamdia branneri and Rhamdia voulezi are morphologically similar species that, until recently, were considered synonymous. Although R. quelen has wide distribution in the Neotropical region, R. branneri and R. voulezi are sympatric and endemic species of the Iguaçu River basin.
Thaís Souto Bignotto+4 more
wiley +1 more source
Evolution of two metabolic genes involved in nucleotide and amino acid metabolism in Pseudomonas aeruginosa. [PDF]
Wu Y, Shi Y, Liang X.
europepmc +1 more source
Late blight pathogen targets host Rab‐G3 GTPases with an atypical GTPase‐activating protein
The Phytophthora infestans RXLR effector Pi17063 functions as an atypical GTPase‐activating protein of host positive immune regulators, specifically the small GTPase NbRab‐G3. Pi17063 promotes the relocalization of NbRab‐G3 proteins to the cytoplasm, where they are inactive, disrupting the balance of the NbRab‐G3 switch and thus leading to enhanced ...
Song Liu+13 more
wiley +1 more source