Results 31 to 40 of about 118,645 (287)

Rhamnose-Containing Compounds: Biosynthesis and Applications

open access: yesMolecules, 2022
Rhamnose-associated molecules are attracting attention because they are present in bacteria but not mammals, making them potentially useful as antibacterial agents. Additionally, they are also valuable for tumor immunotherapy.
Siqiang Li   +6 more
doaj   +1 more source

Combinatorial modular pathway engineering for guanosine 5'-diphosphate-L-fucose production in recombinant Escherichia coli.

open access: yesJournal of Agricultural and Food Chemistry, 2020
Guanosine 5'-diphosphate (GDP)-L-fucose is a vital nucleotide sugar involved in the synthesis of fucosylated oligosaccharides, such as fucosylated human milk oligosaccharides, which play important roles in physiological and pathological processes.
L. Wan   +4 more
semanticscholar   +1 more source

Role of ARHGEF3 as a GEF and mTORC2 Regulator

open access: yesFrontiers in Cell and Developmental Biology, 2022
Guanine nucleotide exchange factors (GEFs) activate GTPases by stimulating the release of guanosine diphosphate to permit the binding of guanosine triphosphate.
Sana Abdul Khaliq   +5 more
doaj   +1 more source

SpoT Induces Intracellular Salmonella Virulence Programs in the Phagosome. [PDF]

open access: yes, 2020
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion ...
Fitzsimmons, Liam F   +8 more
core   +1 more source

Gαs slow conformational transition upon GTP binding and a novel Gαs regulator

open access: yesiScience, 2023
Summary: G proteins are major signaling partners for G protein-coupled receptors (GPCRs). Although stepwise structural changes during GPCR–G protein complex formation and guanosine diphosphate (GDP) release have been reported, no information is available
Donghoon Ahn   +12 more
doaj   +1 more source

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

open access: yes, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz   +60 more
core   +2 more sources

AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression

open access: yesJournal of Pharmacological Sciences, 2008
AMP-activated protein kinase (AMPK) activation has an antiapoptotic effect in endothelial cells, but the mechanisms involved remain unclear. Here, we investigated whether AMPK activation could inhibit palmitate-induced apoptosis through suppression of ...
Ji-Eun Kim   +5 more
doaj   +1 more source

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp), guanosine 5'-diphosphate 3'-monophosphate (ppGp) and antibiotic production in Streptomyces clavuligerus [PDF]

open access: yesMicrobiology, 1996
Streptomyces clavuligerus produced cephamycin C under all nutrient limitations investigated in batch culture, whilst clavulanic acid was produced under phosphate and carbon limitations. Guanosine 5′-diphosphate 3′-diphosphate (ppGpp) was produced at very low levels in all fermentations, prior to the detection of cephamycin C in the fermentation broth ...
C. Jones, A. Thompson, R. England
openaire   +1 more source

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