A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DksA protein during the stringent response. [PDF]
Gummesson B, Lovmar M, Nyström T.
europepmc +3 more sources
Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. [PDF]
Tapscott T +6 more
europepmc +3 more sources
The search for guanosine tetraphosphate (ppGpp) and other unusual nucleotides in eucaryotes. [PDF]
Robert H. Silverman, A G Atherly
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Bacteria export alarmone synthetases that produce (p)ppApp and (p)ppGpp [PDF]
Guanosine penta- and tetraphosphate [(p)ppGpp] and their adenosine analogs [(p)ppApp] are bacterial second messengers known as alarmones. Members of the RelA-SpoT homolog (RSH) family synthesize (p)ppGpp to mediate the stringent response during nutrient ...
Shehryar Ahmad +10 more
doaj +2 more sources
Adaptation of a fluoroquinolone-sensitive Shigella sonnei to norfloxacin exposure [PDF]
Shigella causes shigellosis that requires antibiotic treatment in severe cases. Sublethal antibiotic concentrations can promote resistance, but their effect on antibiotic-sensitive bacteria before resistance development is unclear.
Bao Chi Wong +4 more
doaj +2 more sources
Guanosine tetraphosphate modulates salicylic acid signalling and the resistance of Arabidopsis thaliana to Turnip mosaic virus. [PDF]
Abdelkefi H +9 more
europepmc +3 more sources
Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp. [PDF]
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Zegarra V +7 more
europepmc +2 more sources
Guanosine pentaphosphate and guanosine tetraphosphate are collectively called (p)ppGpp (Guanosine tetraphosphate and pentaphosphate). (p)ppGpp content in plants is affected by conditions such as light, salt, pH, UV light, and environmental phytohormones.
Mengru Wang +7 more
doaj +1 more source
Research on nucleotide-based second messengers began in 1956 with the discovery of cyclic adenosine monophosphate (3′,5′-cAMP) by Earl Wilbur Sutherland and his co-workers.
Frank Braun +4 more
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