New perspectives on the molecular mechanisms of stress signalling by the nucleotide guanosine tetraphosphate (ppGpp), an emerging regulator of photosynthesis in plants and algae [PDF]
New Phytologist, 2023 Summary The nucleotides guanosine tetraphosphate and guanosine pentaphosphate (together (p)ppGpp) are found in a wide range of prokaryotic and eukaryotic organisms where they are associated with stress signalling.
Ben Field
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Guanosine tetraphosphate modulates salicylic acid signalling and the resistance of Arabidopsis thaliana to Turnip mosaic virus [PDF]
Molecular Plant Pathology, 2018 International audienceChloroplasts can act as key players in the perception and acclimatization of plants to incoming environmental signals. A growing body of evidence indicates that chloroplasts play a critical role in plant immunity.
Hela Abdelkefi +2 more
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Guanosine tetraphosphate (ppGpp) is a new player in Brassica napus L. seed development
Food Chemistry, 2023 Rapeseed oil, constituting 12% of global vegetable oil production, is susceptible to quality degradation due to stress-induced incomplete seed degreening, fatty acid oxidation, or poor nutrient accumulation. We hypothesise that the hyperphosphorylated nucleotide alarmone ppGpp (guanosine tetraphosphate), acts as a pivotal regulator of these processes ...
Turkan, Sena +9 more
semanticscholar +4 more sources
Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region. [PDF]
Sci Rep, 2018 The repressive activity of ancestral histone-like proteins helps integrate transcription of foreign genes with discrepant AT content into existing regulatory networks. Our investigations indicate that the AT-rich discriminator region located between the −
Tapscott T +6 more
europepmc +3 more sources
A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DksA protein during the stringent response. [PDF]
J Biol Chem, 2013 Background: ppGpp/DksA regulate genes both positively and negatively during stringency. Results: Positive control by ppGpp/DksA is linked to RNA polymerase-promoter saturation kinetics dependent on the promoter's discriminator.
Gummesson B, Lovmar M, Nyström T.
europepmc +3 more sources
bioRxiv, 2021 The nucleotides guanosine tetraphosphate and pentaphosphate (or ppGpp) are implicated in the regulation of chloroplast function in plants. ppGpp signalling is best understood in the model vascular plant Arabidopsis thaliana where it acts to regulate ...
Seddik Harchouni +8 more
semanticscholar +2 more sources
mBio, 2018 The adaptations that protect pathogenic microorganisms against the cytotoxicity of nitric oxide (NO) engendered in the immune response are incompletely understood.
Liam F. Fitzsimmons +4 more
doaj +3 more sources
Control of rRNA and tRNA syntheses in Escherichia coli by guanosine tetraphosphate [PDF]
Journal of Bacteriology, 1982 The expression of stable RNA (rRNA and tRNA) genes and the concentration of guanosine tetraphosphate (ppGpp) were measured in an isogenic pair of relA+ and relA derivatives of Escherichia coli B/r. The cells were either growing exponentially at different rates or subject to amino acid starvation when they were measured.
J, Ryals, R, Little, H, Bremer
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Regulation of Phospholipid Synthesis in Escherichia coli by Guanosine Tetraphosphate [PDF]
Journal of Bacteriology, 1973 Phospholipid synthesis has been reported to be subject to stringent control in Escherichia coli . We present evidence that demonstrates a strict correlation between guanosine tetraphosphate accumulation and inhibition of phospholipid synthesis.
J P, Merlie, L I, Pizer
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Variation in guanosine 5' ,3'-tetraphosphate levels in Chromatium [PDF]
Journal of Bacteriology, 1977 Chromatium produces guanosine 5' ,3'-tetraphosphate, but there appears to be no correlation between guanosine 5' ,3'-tetraphosphate concentration and the inability of the organism to grow in certain light-dark regimes.
G, Klaussmann, M, Miović
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